FDFT1 (farnesyl-diphosphate farnesyltransferase 1)

Identity

Other names	DGPT
	ERG9
	SQS
	SS
HGNC	FDFT1
Location	8p23.1-p22
Location_base_pair	Starts at 11697599 and ends at 11734227 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	FDFT1   3629
Entrez_Gene	FDFT1  2222  farnesyl-diphosphate farnesyltransferase 1
	Cards
GeneCards	FDFT1
Ensembl	FDFT1 [Search_View]   ENSG00000079459 [Gene_View]
Genatlas	FDFT1
GeneLynx	FDFT1
eGenome	FDFT1
euGene	2222
	Genomic and cartography
GoldenPath	FDFT1  -     chr8:11697599-11734227 +  8p23.1   [Description]    (hg18-March_2006)
Ensembl	FDFT1 - 8p23.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	FDFT1
	Gene and transcription
Genbank	AI679762 [ ENTREZ ]
Genbank	AK057726 [ ENTREZ ]
Genbank	AK098682 [ ENTREZ ]
Genbank	AK300059 [ ENTREZ ]
Genbank	AK301617 [ ENTREZ ]
RefSeq	NM_004462 [ SRS ]    NM_004462 [ ENTREZ ]
RefSeq	AC_000051 [ SRS ]    AC_000051 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_077531 [ SRS ]    NT_077531 [ ENTREZ ]
RefSeq	NW_001839122 [ SRS ]    NW_001839122 [ ENTREZ ]
RefSeq	NW_923873 [ SRS ]    NW_923873 [ ENTREZ ]
AceView	FDFT1 AceView - NCBI
Unigene	Hs.593928 [ SRS ]    Hs.593928 [ NCBI ]     HS593928 [ spliceNest ]
Fast-db	1346 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P37268 [ SRS]    P37268 [ EXPASY ]     P37268 [ INTERPRO ]     P37268 [ UNIPROT ]
Prosite	PS01044 SQUALEN_PHYTOEN_SYN_1 [ SRS ]    PS01044 SQUALEN_PHYTOEN_SYN_1 [ Expasy ]
Prosite	PS01045 SQUALEN_PHYTOEN_SYN_2 [ SRS ]    PS01045 SQUALEN_PHYTOEN_SYN_2 [ Expasy ]
Interpro	IPR002060 Squ/phyt_synthse [ SRS ]    IPR002060 Squ/phyt_synthse [ EBI ]
Interpro	IPR006449 Squal_synth [ SRS ]    IPR006449 Squal_synth [ EBI ]
Interpro	IPR008949 Terpenoid_synth [ SRS ]    IPR008949 Terpenoid_synth [ EBI ]
CluSTr	P37268
Pfam	PF00494 SQS_PSY [ SRS ]    PF00494 SQS_PSY [ Sanger ]    pfam00494 [ NCBI-CDD ]
Blocks	P37268
PDB	1EZF [ SRS ]    1EZF [ PdbSum ],   1EZF [ IMB ]   1EZF [ RSDB ]
HPRD	01694
	Protein Interaction databases
DIP	P37268
IntAct	P37268
	Polymorphism : SNP, mutations, diseases
OMIM	184420    [ map ]
GENECLINICS	184420
SNP	FDFT1 [dbSNP-NCBI]
SNP	NM_004462 [SNP-NCI]
SNP	FDFT1 [GeneSNPs - Utah]  FDFT1] [HGBASE - SRS]
HAPMAP	FDFT1 [HAPMAP]
HGMD	FDFT1
	General knowledge
Family Browser	FDFT1 [UCSC Family Browser]
SOURCE	NM_004462
SMD	Hs.593928
SAGE	Hs.593928
Enzyme	2.5.1.21 [ Enzyme-Expasy ]   2.5.1.21 [ Enzyme-SRS ]   2.5.1.21 [ IntEnz-EBI ]   2.5.1.21 [ BRENDA ]   2.5.1.21 [ KEGG ]   2.5.1.21 [ WIT ]
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	farnesyl-diphosphate farnesyltransferase activity [Amigo]  farnesyl-diphosphate farnesyltransferase activity
GO	farnesyl-diphosphate farnesyltransferase activity [Amigo]  farnesyl-diphosphate farnesyltransferase activity
GO	protein binding [Amigo]  protein binding
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	endoplasmic reticulum membrane [Amigo]  endoplasmic reticulum membrane
GO	endoplasmic reticulum membrane [Amigo]  endoplasmic reticulum membrane
GO	cholesterol biosynthetic process [Amigo]  cholesterol biosynthetic process
GO	isoprenoid biosynthetic process [Amigo]  isoprenoid biosynthetic process
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	oxidoreductase activity [Amigo]  oxidoreductase activity
GO	transferase activity [Amigo]  transferase activity
GO	oxidation reduction [Amigo]  oxidation reduction
KEGG	Biosynthesis of steroids
KEGG	Terpenoid biosynthesis
PubGene	FDFT1
TreeFam	FDFT1
CTD	2222 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	FDFT1 Related clones (RZPD - Berlin)
	PubMed
PubMed	17 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:41:19 2008