GAD2 (glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa))

Identity

Other names	GAD65
	MGC161605
	MGC161607
HGNC	GAD2
Location	10p13-p11.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	GAD2   4093
Entrez_Gene	GAD2  2572  glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
	Cards
GeneCards	GAD2
Ensembl	GAD2 [Search_View]   ENSG00000136750 [Gene_View]
Genatlas	GAD2
GeneLynx	GAD2
eGenome	GAD2
euGene	2572
	Genomic and cartography
GoldenPath	GAD2  -     chr10:26545600-26633493 +  10p12.1   [Description]    (hg18-March_2006)
Ensembl	GAD2 - 10p12.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	GAD2
	Gene and transcription
Genbank	AJ251501 [ ENTREZ ]
Genbank	AK127375 [ ENTREZ ]
Genbank	BC029517 [ ENTREZ ]
Genbank	BC039038 [ ENTREZ ]
Genbank	BC126327 [ ENTREZ ]
RefSeq	NM_000818 [ SRS ]    NM_000818 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_008705 [ SRS ]    NT_008705 [ ENTREZ ]
RefSeq	NW_001837931 [ SRS ]    NW_001837931 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
AceView	GAD2 AceView - NCBI
Unigene	Hs.231829 [ SRS ]    Hs.231829 [ NCBI ]     HS231829 [ spliceNest ]
Fast-db	5994 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q05329 [ SRS]    Q05329 [ EXPASY ]     Q05329 [ INTERPRO ]     Q05329 [ UNIPROT ]
Prosite	PS00392 DDC_GAD_HDC_YDC [ SRS ]    PS00392 DDC_GAD_HDC_YDC [ Expasy ]
Interpro	IPR002129 PyrdxlP-dep_de-COase [ SRS ]    IPR002129 PyrdxlP-dep_de-COase [ EBI ]
CluSTr	Q05329
Pfam	PF00282 Pyridoxal_deC [ SRS ]    PF00282 Pyridoxal_deC [ Sanger ]    pfam00282 [ NCBI-CDD ]
Blocks	Q05329
PDB	1ES0 [ SRS ]    1ES0 [ PdbSum ],   1ES0 [ IMB ]   1ES0 [ RSDB ]
PDB	2OKK [ SRS ]    2OKK [ PdbSum ],   2OKK [ IMB ]   2OKK [ RSDB ]
HPRD	11817
	Protein Interaction databases
DIP	Q05329
IntAct	Q05329
	Polymorphism : SNP, mutations, diseases
OMIM	138275    [ map ]
GENECLINICS	138275
SNP	GAD2 [dbSNP-NCBI]
SNP	NM_000818 [SNP-NCI]
SNP	GAD2 [GeneSNPs - Utah]  GAD2] [HGBASE - SRS]
HAPMAP	GAD2 [HAPMAP]
HGMD	GAD2
	General knowledge
Family Browser	GAD2 [UCSC Family Browser]
SOURCE	NM_000818
SMD	Hs.231829
SAGE	Hs.231829
Enzyme	4.1.1.15 [ Enzyme-Expasy ]   4.1.1.15 [ Enzyme-SRS ]   4.1.1.15 [ IntEnz-EBI ]   4.1.1.15 [ BRENDA ]   4.1.1.15 [ KEGG ]   4.1.1.15 [ WIT ]
GO	Golgi membrane [Amigo]  Golgi membrane
GO	glutamate decarboxylase activity [Amigo]  glutamate decarboxylase activity
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	Golgi apparatus [Amigo]  Golgi apparatus
GO	glutamate decarboxylation to succinate [Amigo]  glutamate decarboxylation to succinate
GO	synaptic transmission [Amigo]  synaptic transmission
GO	membrane [Amigo]  membrane
GO	lyase activity [Amigo]  lyase activity
GO	carboxy-lyase activity [Amigo]  carboxy-lyase activity
GO	carboxylic acid metabolic process [Amigo]  carboxylic acid metabolic process
GO	cell junction [Amigo]  cell junction
GO	pyridoxal phosphate binding [Amigo]  pyridoxal phosphate binding
GO	cytoplasmic vesicle [Amigo]  cytoplasmic vesicle
GO	neurotransmitter biosynthetic process [Amigo]  neurotransmitter biosynthetic process
GO	synapse [Amigo]  synapse
KEGG	Glutamate metabolism
KEGG	Alanine and aspartate metabolism
KEGG	beta-Alanine metabolism
KEGG	Taurine and hypotaurine metabolism
KEGG	Butanoate metabolism
KEGG	Type I diabetes mellitus
PubGene	GAD2
TreeFam	GAD2
CTD	2572 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	GAD2 Related clones (RZPD - Berlin)
	PubMed
PubMed	54 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:12:04 2008