GAPDH (glyceraldehyde-3-phosphate dehydrogenase)

Identity

Other names	G3PD
	GAPD
	MGC88685
HGNC	GAPDH
Location	12p13.31
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	GAPDH   4141
Entrez_Gene	GAPDH  2597  glyceraldehyde-3-phosphate dehydrogenase
	Cards
GeneCards	GAPDH
Ensembl	GAPDH [Search_View]   ENSG00000111640 [Gene_View]
Genatlas	GAPDH
GeneLynx	GAPDH
eGenome	GAPDH
euGene	2597
	Genomic and cartography
GoldenPath	GAPDH  -  12p13.31   chr12:6513918-6517797 +  12p13.31   [Description]    (hg18-March_2006)
Ensembl	GAPDH - 12p13.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	GAPDH
	Gene and transcription
Genbank	AB062273 [ ENTREZ ]
Genbank	AF261085 [ ENTREZ ]
Genbank	AJ844645 [ ENTREZ ]
Genbank	AK026525 [ ENTREZ ]
Genbank	AK308198 [ ENTREZ ]
RefSeq	NM_002046 [ SRS ]    NM_002046 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NG_007073 [ SRS ]    NG_007073 [ ENTREZ ]
RefSeq	NT_009759 [ SRS ]    NT_009759 [ ENTREZ ]
RefSeq	NW_001838050 [ SRS ]    NW_001838050 [ ENTREZ ]
RefSeq	NW_925295 [ SRS ]    NW_925295 [ ENTREZ ]
AceView	GAPDH AceView - NCBI
Unigene	Hs.711936 [ SRS ]    Hs.711936 [ NCBI ]     HS711936 [ spliceNest ]
Fast-db	1066 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P04406 [ SRS]    P04406 [ EXPASY ]     P04406 [ INTERPRO ]     P04406 [ UNIPROT ]
Prosite	PS00071 GAPDH [ SRS ]    PS00071 GAPDH [ Expasy ]
Interpro	IPR000173 GlycerAld_3-P_DHase [ SRS ]    IPR000173 GlycerAld_3-P_DHase [ EBI ]
Interpro	IPR006424 Glyceraldehyde-3-P_DHase_1 [ SRS ]    IPR006424 Glyceraldehyde-3-P_DHase_1 [ EBI ]
CluSTr	P04406
Pfam	PF02800 Gp_dh_C [ SRS ]    PF02800 Gp_dh_C [ Sanger ]    pfam02800 [ NCBI-CDD ]
Pfam	PF00044 Gp_dh_N [ SRS ]    PF00044 Gp_dh_N [ Sanger ]    pfam00044 [ NCBI-CDD ]
Blocks	P04406
PDB	1U8F [ SRS ]    1U8F [ PdbSum ],   1U8F [ IMB ]   1U8F [ RSDB ]
PDB	1ZNQ [ SRS ]    1ZNQ [ PdbSum ],   1ZNQ [ IMB ]   1ZNQ [ RSDB ]
PDB	2FEH [ SRS ]    2FEH [ PdbSum ],   2FEH [ IMB ]   2FEH [ RSDB ]
PDB	3GPD [ SRS ]    3GPD [ PdbSum ],   3GPD [ IMB ]   3GPD [ RSDB ]
HPRD	00713
	Protein Interaction databases
DIP	P04406
IntAct	P04406
	Polymorphism : SNP, mutations, diseases
OMIM	138400    [ map ]
GENECLINICS	138400
SNP	GAPDH [dbSNP-NCBI]
SNP	NM_002046 [SNP-NCI]
SNP	GAPDH [GeneSNPs - Utah]  GAPDH] [HGBASE - SRS]
HAPMAP	GAPDH [HAPMAP]
COSMIC	GAPDH [Somatic mutation (COSMIC-CGP-Sanger)]
TICdb	catalytic [Translocation breakpoints In Cancer]
HGMD	GAPDH
	General knowledge
Family Browser	GAPDH [UCSC Family Browser]
SOURCE	NM_002046
SMD	Hs.711936
SAGE	Hs.711936
GO	catalytic activity [Amigo]  catalytic activity
GO	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity [Amigo]  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
GO	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity [Amigo]  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
GO	binding [Amigo]  binding
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	glucose metabolic process [Amigo]  glucose metabolic process
GO	glycolysis [Amigo]  glycolysis
GO	metabolic process [Amigo]  metabolic process
GO	membrane [Amigo]  membrane
GO	oxidoreductase activity [Amigo]  oxidoreductase activity
GO	NAD binding [Amigo]  NAD binding
GO	oxidation reduction [Amigo]  oxidation reduction
BIOCARTA	Glycolysis Pathway    [Genes]
BIOCARTA	Downregulated of MTA-3 in ER-negative Breast Tumors    [Genes]
KEGG	Glycolysis / Gluconeogenesis
KEGG	Neurodegenerative Disorders
KEGG	Alzheimer's disease
KEGG	Huntington's disease
KEGG	Dentatorubropallidoluysian atrophy (DRPLA)
PubGene	GAPDH
TreeFam	GAPDH
CTD	2597 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	GAPDH Related clones (RZPD - Berlin)
	PubMed
PubMed	120 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:12:13 2008