GATA4 (GATA binding protein 4)

Identity

Other names	MGC126629
HGNC	GATA4
Location	8p23.1-p22
Location_base_pair	Starts at 11599126 and ends at 11654918 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	GATA4   4173
Entrez_Gene	GATA4  2626  GATA binding protein 4
	Cards
GeneCards	GATA4
Ensembl	GATA4 [Search_View]   ENSG00000136574 [Gene_View]
Genatlas	GATA4
GeneLynx	GATA4
eGenome	GATA4
euGene	2626
	Genomic and cartography
GoldenPath	GATA4  -     chr8:11599126-11654918 +  8p23.1   [Description]    (hg18-March_2006)
Ensembl	GATA4 - 8p23.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	GATA4
	Gene and transcription
Genbank	AF180736 [ ENTREZ ]
Genbank	AF318320 [ ENTREZ ]
Genbank	AK097060 [ ENTREZ ]
Genbank	AY740706 [ ENTREZ ]
Genbank	BC033672 [ ENTREZ ]
RefSeq	NM_002052 [ SRS ]    NM_002052 [ ENTREZ ]
RefSeq	AC_000051 [ SRS ]    AC_000051 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NG_008177 [ SRS ]    NG_008177 [ ENTREZ ]
RefSeq	NT_077531 [ SRS ]    NT_077531 [ ENTREZ ]
RefSeq	NW_001839122 [ SRS ]    NW_001839122 [ ENTREZ ]
RefSeq	NW_923873 [ SRS ]    NW_923873 [ ENTREZ ]
AceView	GATA4 AceView - NCBI
Unigene	Hs.243987 [ SRS ]    Hs.243987 [ NCBI ]     HS243987 [ spliceNest ]
Fast-db	1326 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P43694 [ SRS]    P43694 [ EXPASY ]     P43694 [ INTERPRO ]     P43694 [ UNIPROT ]
Prosite	PS00344 GATA_ZN_FINGER_1 [ SRS ]    PS00344 GATA_ZN_FINGER_1 [ Expasy ]
Prosite	PS50114 GATA_ZN_FINGER_2 [ SRS ]    PS50114 GATA_ZN_FINGER_2 [ Expasy ]
Interpro	IPR008013 GATA_N [ SRS ]    IPR008013 GATA_N [ EBI ]
Interpro	IPR016375 TF_GATA_4/5/6 [ SRS ]    IPR016375 TF_GATA_4/5/6 [ EBI ]
Interpro	IPR000679 Znf_GATA [ SRS ]    IPR000679 Znf_GATA [ EBI ]
Interpro	IPR013088 Znf_NHR/GATA [ SRS ]    IPR013088 Znf_NHR/GATA [ EBI ]
CluSTr	P43694
Pfam	PF00320 GATA [ SRS ]    PF00320 GATA [ Sanger ]    pfam00320 [ NCBI-CDD ]
Pfam	PF05349 GATA-N [ SRS ]    PF05349 GATA-N [ Sanger ]    pfam05349 [ NCBI-CDD ]
Smart	SM00401 ZnF_GATA [EMBL]
Blocks	P43694
HPRD	08994
	Protein Interaction databases
DIP	P43694
IntAct	P43694
	Polymorphism : SNP, mutations, diseases
OMIM	600576;607941    [ map ]
GENECLINICS	600576;607941
SNP	GATA4 [dbSNP-NCBI]
SNP	NM_002052 [SNP-NCI]
SNP	GATA4 [GeneSNPs - Utah]  GATA4] [HGBASE - SRS]
HAPMAP	GATA4 [HAPMAP]
HGMD	GATA4
	General knowledge
Family Browser	GATA4 [UCSC Family Browser]
SOURCE	NM_002052
SMD	Hs.243987
SAGE	Hs.243987
GO	positive regulation of cytokine production [Amigo]  positive regulation of cytokine production
GO	heart looping [Amigo]  heart looping
GO	DNA binding [Amigo]  DNA binding
GO	transcription factor activity [Amigo]  transcription factor activity
GO	transcription factor activity [Amigo]  transcription factor activity
GO	specific RNA polymerase II transcription factor activity [Amigo]  specific RNA polymerase II transcription factor activity
GO	protein binding [Amigo]  protein binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleus [Amigo]  nucleus
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	transcription from RNA polymerase II promoter [Amigo]  transcription from RNA polymerase II promoter
GO	cell-cell signaling [Amigo]  cell-cell signaling
GO	zinc ion binding [Amigo]  zinc ion binding
GO	transcription activator activity [Amigo]  transcription activator activity
GO	embryonic heart tube anterior/posterior pattern formation [Amigo]  embryonic heart tube anterior/posterior pattern formation
GO	positive regulation of gene-specific transcription [Amigo]  positive regulation of gene-specific transcription
GO	sequence-specific DNA binding [Amigo]  sequence-specific DNA binding
GO	positive regulation of angiogenesis [Amigo]  positive regulation of angiogenesis
GO	positive regulation of transcription [Amigo]  positive regulation of transcription
GO	metal ion binding [Amigo]  metal ion binding
GO	embryonic foregut morphogenesis [Amigo]  embryonic foregut morphogenesis
BIOCARTA	ALK in cardiac myocytes    [Genes]
BIOCARTA	Hop Pathway in Cardiac Development    [Genes]
BIOCARTA	NFAT and Hypertrophy of the heart (Transcription in the broken heart)    [Genes]
PubGene	GATA4
TreeFam	GATA4
CTD	2626 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	GATA4 Related clones (RZPD - Berlin)
	PubMed
PubMed	67 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:42:44 2008