HCN1 (hyperpolarization activated cyclic nucleotide-gated potassium channel 1)

Identity

Other names	BCNG-1
	BCNG1
	HAC-2
HGNC	HCN1
Location	5p12
Location_base_pair	Starts at 45295109 and ends at 45731977 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	HCN1   4845
Entrez_Gene	HCN1  348980  hyperpolarization activated cyclic nucleotide-gated potassium channel 1
	Cards
GeneCards	HCN1
Ensembl	HCN1 [Search_View]   ENSG00000164588 [Gene_View]
Genatlas	HCN1
GeneLynx	HCN1
eGenome	HCN1
euGene	348980
	Genomic and cartography
GoldenPath	HCN1  -  5p12   chr5:45295109-45731977 -  5p12   [Description]    (hg18-March_2006)
Ensembl	HCN1 - 5p12 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HCN1
	Gene and transcription
Genbank	AF064876 [ ENTREZ ]
Genbank	AF488549 [ ENTREZ ]
Genbank	AK094523 [ ENTREZ ]
Genbank	BC156454 [ ENTREZ ]
Genbank	BM931647 [ ENTREZ ]
RefSeq	NM_021072 [ SRS ]    NM_021072 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_006576 [ SRS ]    NT_006576 [ ENTREZ ]
RefSeq	NW_001838933 [ SRS ]    NW_001838933 [ ENTREZ ]
RefSeq	NW_922596 [ SRS ]    NW_922596 [ ENTREZ ]
AceView	HCN1 AceView - NCBI
Unigene	Hs.650434 [ SRS ]    Hs.650434 [ NCBI ]     HS650434 [ spliceNest ]
Fast-db	3705 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O60741 [ SRS]    O60741 [ EXPASY ]     O60741 [ INTERPRO ]     O60741 [ UNIPROT ]
Prosite	PS00888 CNMP_BINDING_1 [ SRS ]    PS00888 CNMP_BINDING_1 [ Expasy ]
Prosite	PS00889 CNMP_BINDING_2 [ SRS ]    PS00889 CNMP_BINDING_2 [ Expasy ]
Prosite	PS50042 CNMP_BINDING_3 [ SRS ]    PS50042 CNMP_BINDING_3 [ Expasy ]
Interpro	IPR000595 cNMP_bd [ SRS ]    IPR000595 cNMP_bd [ EBI ]
Interpro	IPR005821 Ion_trans [ SRS ]    IPR005821 Ion_trans [ EBI ]
Interpro	IPR013621 Ion_trans_N [ SRS ]    IPR013621 Ion_trans_N [ EBI ]
Interpro	IPR003938 K_chnl_volt-dep_EAG/ELK/ERG [ SRS ]    IPR003938 K_chnl_volt-dep_EAG/ELK/ERG [ EBI ]
Interpro	IPR014710 RmlC-like_jellyroll [ SRS ]    IPR014710 RmlC-like_jellyroll [ EBI ]
CluSTr	O60741
Pfam	PF00027 cNMP_binding [ SRS ]    PF00027 cNMP_binding [ Sanger ]    pfam00027 [ NCBI-CDD ]
Pfam	PF00520 Ion_trans [ SRS ]    PF00520 Ion_trans [ Sanger ]    pfam00520 [ NCBI-CDD ]
Pfam	PF08412 Ion_trans_N [ SRS ]    PF08412 Ion_trans_N [ Sanger ]    pfam08412 [ NCBI-CDD ]
Smart	SM00100 cNMP [EMBL]
Blocks	O60741
HPRD	09099
	Protein Interaction databases
DIP	O60741
IntAct	O60741
	Polymorphism : SNP, mutations, diseases
OMIM	602780    [ map ]
GENECLINICS	602780
SNP	HCN1 [dbSNP-NCBI]
SNP	NM_021072 [SNP-NCI]
SNP	HCN1 [GeneSNPs - Utah]  HCN1] [HGBASE - SRS]
HAPMAP	HCN1 [HAPMAP]
HGMD	HCN1
	General knowledge
Family Browser	HCN1 [UCSC Family Browser]
SOURCE	NM_021072
SMD	Hs.650434
SAGE	Hs.650434
GO	nucleotide binding [Amigo]  nucleotide binding
GO	voltage-gated ion channel activity [Amigo]  voltage-gated ion channel activity
GO	voltage-gated potassium channel activity [Amigo]  voltage-gated potassium channel activity
GO	sodium channel activity [Amigo]  sodium channel activity
GO	protein binding [Amigo]  protein binding
GO	ion transport [Amigo]  ion transport
GO	potassium ion transport [Amigo]  potassium ion transport
GO	sodium ion transport [Amigo]  sodium ion transport
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	axon [Amigo]  axon
GO	dendrite [Amigo]  dendrite
GO	cAMP binding [Amigo]  cAMP binding
GO	potassium ion binding [Amigo]  potassium ion binding
GO	sodium ion binding [Amigo]  sodium ion binding
GO	apical protein localization [Amigo]  apical protein localization
PubGene	HCN1
TreeFam	HCN1
CTD	348980 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	HCN1 Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:44:22 2008