HDAC2 (histone deacetylase 2)

Identity

Other names	RPD3
	YAF1
HGNC	HDAC2
Location	6q21
Location_base_pair	Starts at 114364020 and ends at 114399047 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	HDAC2   4853
Entrez_Gene	HDAC2  3066  histone deacetylase 2
	Cards
GeneCards	HDAC2
Ensembl	HDAC2 [Search_View]   ENSG00000196591 [Gene_View]
Genatlas	HDAC2
GeneLynx	HDAC2
eGenome	HDAC2
euGene	3066
	Genomic and cartography
GoldenPath	HDAC2  -  6q21   chr6:114364020-114399047 -  6q22.1   [Description]    (hg18-March_2006)
Ensembl	HDAC2 - 6q22.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HDAC2
	Gene and transcription
Genbank	AA704179 [ ENTREZ ]
Genbank	AB209190 [ ENTREZ ]
Genbank	AK092156 [ ENTREZ ]
Genbank	AK097376 [ ENTREZ ]
Genbank	AV719958 [ ENTREZ ]
RefSeq	NM_001527 [ SRS ]    NM_001527 [ ENTREZ ]
RefSeq	AC_000049 [ SRS ]    AC_000049 [ ENTREZ ]
RefSeq	AC_000138 [ SRS ]    AC_000138 [ ENTREZ ]
RefSeq	NC_000006 [ SRS ]    NC_000006 [ ENTREZ ]
RefSeq	NT_025741 [ SRS ]    NT_025741 [ ENTREZ ]
RefSeq	NW_001838990 [ SRS ]    NW_001838990 [ ENTREZ ]
RefSeq	NW_923184 [ SRS ]    NW_923184 [ ENTREZ ]
AceView	HDAC2 AceView - NCBI
Unigene	Hs.3352 [ SRS ]    Hs.3352 [ NCBI ]     HS3352 [ spliceNest ]
Fast-db	16230 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q59GB9 [ SRS]    Q59GB9 [ EXPASY ]     Q59GB9 [ INTERPRO ]     Q59GB9 [ UNIPROT ]
Interpro	IPR000286 His_deacetylse [ SRS ]    IPR000286 His_deacetylse [ EBI ]
Interpro	IPR003084 His_deacetylse_1 [ SRS ]    IPR003084 His_deacetylse_1 [ EBI ]
CluSTr	Q59GB9
Pfam	PF00850 Hist_deacetyl [ SRS ]    PF00850 Hist_deacetyl [ Sanger ]    pfam00850 [ NCBI-CDD ]
Blocks	Q59GB9
HPRD	05521
	Protein Interaction databases
DIP	Q59GB9
IntAct	Q59GB9
	Polymorphism : SNP, mutations, diseases
OMIM	605164    [ map ]
GENECLINICS	605164
SNP	HDAC2 [dbSNP-NCBI]
SNP	NM_001527 [SNP-NCI]
SNP	HDAC2 [GeneSNPs - Utah]  HDAC2] [HGBASE - SRS]
HAPMAP	HDAC2 [HAPMAP]
COSMIC	HDAC2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	HDAC2
	General knowledge
Family Browser	HDAC2 [UCSC Family Browser]
SOURCE	NM_001527
SMD	Hs.3352
SAGE	Hs.3352
GO	histone deacetylase complex [Amigo]  histone deacetylase complex
GO	heterochromatin [Amigo]  heterochromatin
GO	transcription factor activity [Amigo]  transcription factor activity
GO	histone deacetylase activity [Amigo]  histone deacetylase activity
GO	histone deacetylase activity [Amigo]  histone deacetylase activity
GO	nucleus [Amigo]  nucleus
GO	nucleus [Amigo]  nucleus
GO	replication fork [Amigo]  replication fork
GO	cytoplasm [Amigo]  cytoplasm
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	transcription factor binding [Amigo]  transcription factor binding
GO	chromatin modification [Amigo]  chromatin modification
GO	histone deacetylation [Amigo]  histone deacetylation
GO	hydrolase activity [Amigo]  hydrolase activity
GO	enzyme binding [Amigo]  enzyme binding
BIOCARTA	CARM1 and Regulation of the Estrogen Receptor    [Genes]
BIOCARTA	METS affect on Macrophage Differentiation    [Genes]
BIOCARTA	Role of MEF2D in T-cell Apoptosis    [Genes]
BIOCARTA	The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails    [Genes]
KEGG	Cell cycle
KEGG	Notch signaling pathway
PubGene	HDAC2
TreeFam	HDAC2
CTD	3066 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	HDAC2 Related clones (RZPD - Berlin)
	PubMed
PubMed	129 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:44:25 2008