HGFAC (HGF activator)

Identity

Other names	HGFA
	MGC138395
	MGC138397
HGNC	HGFAC
Location	4p16
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	HGFAC   4894
Entrez_Gene	HGFAC  3083  HGF activator
	Cards
GeneCards	HGFAC
Ensembl	HGFAC [Search_View]   ENSG00000109758 [Gene_View]
Genatlas	HGFAC
GeneLynx	HGFAC
eGenome	HGFAC
euGene	3083
	Genomic and cartography
GoldenPath	HGFAC  -  4p16   chr4:3413524-3421011 +  4p16.2   [Description]    (hg18-March_2006)
Ensembl	HGFAC - 4p16.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HGFAC
	Gene and transcription
Genbank	AK314099 [ ENTREZ ]
Genbank	BC112190 [ ENTREZ ]
Genbank	BC112192 [ ENTREZ ]
Genbank	CR626692 [ ENTREZ ]
Genbank	D14012 [ ENTREZ ]
RefSeq	NM_001528 [ SRS ]    NM_001528 [ ENTREZ ]
RefSeq	AC_000047 [ SRS ]    AC_000047 [ ENTREZ ]
RefSeq	AC_000136 [ SRS ]    AC_000136 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NT_006081 [ SRS ]    NT_006081 [ ENTREZ ]
RefSeq	NW_001838896 [ SRS ]    NW_001838896 [ ENTREZ ]
RefSeq	NW_921918 [ SRS ]    NW_921918 [ ENTREZ ]
AceView	HGFAC AceView - NCBI
Unigene	Hs.104 [ SRS ]    Hs.104 [ NCBI ]     HS104 [ spliceNest ]
Fast-db	1656 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q04756 [ SRS]    Q04756 [ EXPASY ]     Q04756 [ INTERPRO ]     Q04756 [ UNIPROT ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS01253 FN1_1 [ SRS ]    PS01253 FN1_1 [ Expasy ]
Prosite	PS51091 FN1_2 [ SRS ]    PS51091 FN1_2 [ Expasy ]
Prosite	PS00023 FN2_1 [ SRS ]    PS00023 FN2_1 [ Expasy ]
Prosite	PS51092 FN2_2 [ SRS ]    PS51092 FN2_2 [ Expasy ]
Prosite	PS00021 KRINGLE_1 [ SRS ]    PS00021 KRINGLE_1 [ Expasy ]
Prosite	PS50070 KRINGLE_2 [ SRS ]    PS50070 KRINGLE_2 [ Expasy ]
Prosite	PS50240 TRYPSIN_DOM [ SRS ]    PS50240 TRYPSIN_DOM [ Expasy ]
Prosite	PS00134 TRYPSIN_HIS [ SRS ]    PS00134 TRYPSIN_HIS [ Expasy ]
Prosite	PS00135 TRYPSIN_SER [ SRS ]    PS00135 TRYPSIN_SER [ Expasy ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR006209 EGF_like [ SRS ]    IPR006209 EGF_like [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR014394 Factor_XII_HGFA [ SRS ]    IPR014394 Factor_XII_HGFA [ EBI ]
Interpro	IPR000083 Fibrnctn1 [ SRS ]    IPR000083 Fibrnctn1 [ EBI ]
Interpro	IPR000562 FN_type2_col_bd [ SRS ]    IPR000562 FN_type2_col_bd [ EBI ]
Interpro	IPR000001 Kringle [ SRS ]    IPR000001 Kringle [ EBI ]
Interpro	IPR001254 Peptidase_S1_S6 [ SRS ]    IPR001254 Peptidase_S1_S6 [ EBI ]
Interpro	IPR001314 Peptidase_S1A [ SRS ]    IPR001314 Peptidase_S1A [ EBI ]
CluSTr	Q04756
Pfam	PF00008 EGF [ SRS ]    PF00008 EGF [ Sanger ]    pfam00008 [ NCBI-CDD ]
Pfam	PF00039 fn1 [ SRS ]    PF00039 fn1 [ Sanger ]    pfam00039 [ NCBI-CDD ]
Pfam	PF00040 fn2 [ SRS ]    PF00040 fn2 [ Sanger ]    pfam00040 [ NCBI-CDD ]
Pfam	PF00051 Kringle [ SRS ]    PF00051 Kringle [ Sanger ]    pfam00051 [ NCBI-CDD ]
Pfam	PF00089 Trypsin [ SRS ]    PF00089 Trypsin [ Sanger ]    pfam00089 [ NCBI-CDD ]
Smart	SM00181 EGF [EMBL]
Smart	SM00058 FN1 [EMBL]
Smart	SM00059 FN2 [EMBL]
Smart	SM00130 KR [EMBL]
Smart	SM00020 Tryp_SPc [EMBL]
Prodom	PD000995 FN_Type_II[INRA-Toulouse]
Prodom	Q04756 HGFA_HUMAN [ Domain structure ]   Q04756 HGFA_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000995[INRA-Toulouse]
Prodom	Q04756 HGFA_HUMAN [ Domain structure ]   Q04756 HGFA_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q04756
PDB	1YBW [ SRS ]    1YBW [ PdbSum ],   1YBW [ IMB ]   1YBW [ RSDB ]
PDB	1YC0 [ SRS ]    1YC0 [ PdbSum ],   1YC0 [ IMB ]   1YC0 [ RSDB ]
PDB	2R0K [ SRS ]    2R0K [ PdbSum ],   2R0K [ IMB ]   2R0K [ RSDB ]
PDB	2R0L [ SRS ]    2R0L [ PdbSum ],   2R0L [ IMB ]   2R0L [ RSDB ]
HPRD	05184
	Protein Interaction databases
DIP	Q04756
IntAct	Q04756
	Polymorphism : SNP, mutations, diseases
OMIM	604552    [ map ]
GENECLINICS	604552
SNP	HGFAC [dbSNP-NCBI]
SNP	NM_001528 [SNP-NCI]
SNP	HGFAC [GeneSNPs - Utah]  HGFAC] [HGBASE - SRS]
HAPMAP	HGFAC [HAPMAP]
HGMD	HGFAC
	General knowledge
Family Browser	HGFAC [UCSC Family Browser]
SOURCE	NM_001528
SMD	Hs.104
SAGE	Hs.104
Enzyme	3.4.21.- [ Enzyme-Expasy ]   3.4.21.- [ Enzyme-SRS ]   3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   3.4.21.- [ WIT ]
GO	serine-type endopeptidase activity [Amigo]  serine-type endopeptidase activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	proteolysis [Amigo]  proteolysis
PubGene	HGFAC
TreeFam	HGFAC
CTD	3083 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	HGFAC Related clones (RZPD - Berlin)
	PubMed
PubMed	19 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:14:06 2008