IRF4 (interferon regulatory factor 4)

Identity

Other names	LSIRF
	MUM1
HGNC	IRF4
Location	6p25-p23
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	IRF4   6119
Entrez_Gene	IRF4  3662  interferon regulatory factor 4
	Cards
GeneCards	IRF4
Ensembl	IRF4 [Search_View]   ENSG00000137265 [Gene_View]
Genatlas	IRF4
GeneLynx	IRF4
eGenome	IRF4
euGene	3662
	Genomic and cartography
GoldenPath	IRF4  -     chr6:336752-356443 +  6p25.3   [Description]    (hg18-March_2006)
Ensembl	IRF4 - 6p25.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	IRF4
	Gene and transcription
Genbank	AK130762 [ ENTREZ ]
Genbank	AK310149 [ ENTREZ ]
Genbank	BC015752 [ ENTREZ ]
Genbank	D78261 [ ENTREZ ]
Genbank	DQ893472 [ ENTREZ ]
RefSeq	NM_002460 [ SRS ]    NM_002460 [ ENTREZ ]
RefSeq	AC_000049 [ SRS ]    AC_000049 [ ENTREZ ]
RefSeq	AC_000138 [ SRS ]    AC_000138 [ ENTREZ ]
RefSeq	NC_000006 [ SRS ]    NC_000006 [ ENTREZ ]
RefSeq	NT_034880 [ SRS ]    NT_034880 [ ENTREZ ]
RefSeq	NW_001838972 [ SRS ]    NW_001838972 [ ENTREZ ]
RefSeq	NW_922984 [ SRS ]    NW_922984 [ ENTREZ ]
AceView	IRF4 AceView - NCBI
Unigene	Hs.401013 [ SRS ]    Hs.401013 [ NCBI ]     HS401013 [ spliceNest ]
Fast-db	654 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q15306 [ SRS]    Q15306 [ EXPASY ]     Q15306 [ INTERPRO ]     Q15306 [ UNIPROT ]
Prosite	PS00601 IRF [ SRS ]    PS00601 IRF [ Expasy ]
Interpro	IPR001346 IRF [ SRS ]    IPR001346 IRF [ EBI ]
Interpro	IPR017855 SMAD_dom-like [ SRS ]    IPR017855 SMAD_dom-like [ EBI ]
Interpro	IPR011991 Wing_hlx_DNA_bd [ SRS ]    IPR011991 Wing_hlx_DNA_bd [ EBI ]
CluSTr	Q15306
Pfam	PF00605 IRF [ SRS ]    PF00605 IRF [ Sanger ]    pfam00605 [ NCBI-CDD ]
Smart	SM00348 IRF [EMBL]
Prodom	PD002355 IRF[INRA-Toulouse]
Prodom	Q15306 IRF4_HUMAN [ Domain structure ]   Q15306 IRF4_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q15306
PDB	2DLL [ SRS ]    2DLL [ PdbSum ],   2DLL [ IMB ]   2DLL [ RSDB ]
HPRD	03543
	Protein Interaction databases
DIP	Q15306
IntAct	Q15306
	Polymorphism : SNP, mutations, diseases
OMIM	601900    [ map ]
GENECLINICS	601900
SNP	IRF4 [dbSNP-NCBI]
SNP	NM_002460 [SNP-NCI]
SNP	IRF4 [GeneSNPs - Utah]  IRF4] [HGBASE - SRS]
HAPMAP	IRF4 [HAPMAP]
COSMIC	IRF4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	IRF4
	General knowledge
Family Browser	IRF4 [UCSC Family Browser]
SOURCE	NM_002460
SMD	Hs.401013
SAGE	Hs.401013
GO	transcription factor activity [Amigo]  transcription factor activity
GO	RNA polymerase II transcription factor activity [Amigo]  RNA polymerase II transcription factor activity
GO	nucleus [Amigo]  nucleus
GO	nucleus [Amigo]  nucleus
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	transcription factor binding [Amigo]  transcription factor binding
GO	transcription activator activity [Amigo]  transcription activator activity
GO	transcription activator activity [Amigo]  transcription activator activity
GO	T cell activation [Amigo]  T cell activation
GO	positive regulation of interleukin-10 biosynthetic process [Amigo]  positive regulation of interleukin-10 biosynthetic process
GO	positive regulation of interleukin-10 biosynthetic process [Amigo]  positive regulation of interleukin-10 biosynthetic process
GO	positive regulation of interleukin-2 biosynthetic process [Amigo]  positive regulation of interleukin-2 biosynthetic process
GO	positive regulation of interleukin-2 biosynthetic process [Amigo]  positive regulation of interleukin-2 biosynthetic process
GO	positive regulation of interleukin-13 biosynthetic process [Amigo]  positive regulation of interleukin-13 biosynthetic process
GO	positive regulation of interleukin-13 biosynthetic process [Amigo]  positive regulation of interleukin-13 biosynthetic process
GO	positive regulation of interleukin-4 biosynthetic process [Amigo]  positive regulation of interleukin-4 biosynthetic process
GO	positive regulation of interleukin-4 biosynthetic process [Amigo]  positive regulation of interleukin-4 biosynthetic process
GO	regulation of T-helper cell differentiation [Amigo]  regulation of T-helper cell differentiation
GO	positive regulation of transcription [Amigo]  positive regulation of transcription
GO	positive regulation of transcription [Amigo]  positive regulation of transcription
PubGene	IRF4
TreeFam	IRF4
CTD	3662 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	IRF4 Related clones (RZPD - Berlin)
	PubMed
PubMed	35 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:16:25 2008