ITGA1 (integrin, alpha 1)

Identity

Other names	CD49a
	VLA1
HGNC	ITGA1
Location	5q11.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ITGA1   6134
Entrez_Gene	ITGA1  3672  integrin, alpha 1
	Cards
GeneCards	ITGA1
Ensembl	ITGA1 [Search_View]   ENSG00000213949 [Gene_View]
Genatlas	ITGA1
GeneLynx	ITGA1
eGenome	ITGA1
euGene	3672
	Genomic and cartography
GoldenPath	ITGA1  -  5q11.1   chr5:52119893-52285242 +  5q11.2   [Description]    (hg18-March_2006)
Ensembl	ITGA1 - 5q11.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ITGA1
	Gene and transcription
Genbank	AK300423 [ ENTREZ ]
Genbank	BC050277 [ ENTREZ ]
Genbank	BC137121 [ ENTREZ ]
Genbank	BC137122 [ ENTREZ ]
Genbank	X68742 [ ENTREZ ]
RefSeq	NM_181501 [ SRS ]    NM_181501 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NG_002793 [ SRS ]    NG_002793 [ ENTREZ ]
RefSeq	NT_006713 [ SRS ]    NT_006713 [ ENTREZ ]
RefSeq	NW_001838934 [ SRS ]    NW_001838934 [ ENTREZ ]
RefSeq	NW_922607 [ SRS ]    NW_922607 [ ENTREZ ]
AceView	ITGA1 AceView - NCBI
Unigene	Hs.644352 [ SRS ]    Hs.644352 [ NCBI ]     HS644352 [ spliceNest ]
Fast-db	3796 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P56199 [ SRS]    P56199 [ EXPASY ]     P56199 [ INTERPRO ]     P56199 [ UNIPROT ]
Prosite	PS00242 INTEGRIN_ALPHA [ SRS ]    PS00242 INTEGRIN_ALPHA [ Expasy ]
Prosite	PS50234 VWFA [ SRS ]    PS50234 VWFA [ Expasy ]
Interpro	IPR013517 FG-GAP [ SRS ]    IPR013517 FG-GAP [ EBI ]
Interpro	IPR013519 Int_alpha_beta-p [ SRS ]    IPR013519 Int_alpha_beta-p [ EBI ]
Interpro	IPR000413 Integrin_alpha [ SRS ]    IPR000413 Integrin_alpha [ EBI ]
Interpro	IPR013649 Integrin_alpha-2 [ SRS ]    IPR013649 Integrin_alpha-2 [ EBI ]
Interpro	IPR013513 Integrin_alpha_C [ SRS ]    IPR013513 Integrin_alpha_C [ EBI ]
Interpro	IPR002035 VWF_A [ SRS ]    IPR002035 VWF_A [ EBI ]
CluSTr	P56199
Pfam	PF01839 FG-GAP [ SRS ]    PF01839 FG-GAP [ Sanger ]    pfam01839 [ NCBI-CDD ]
Pfam	PF08441 Integrin_alpha2 [ SRS ]    PF08441 Integrin_alpha2 [ Sanger ]    pfam08441 [ NCBI-CDD ]
Pfam	PF00092 VWA [ SRS ]    PF00092 VWA [ Sanger ]    pfam00092 [ NCBI-CDD ]
Smart	SM00191 Int_alpha [EMBL]
Smart	SM00327 VWA [EMBL]
Blocks	P56199
PDB	1PT6 [ SRS ]    1PT6 [ PdbSum ],   1PT6 [ IMB ]   1PT6 [ RSDB ]
PDB	1QC5 [ SRS ]    1QC5 [ PdbSum ],   1QC5 [ IMB ]   1QC5 [ RSDB ]
PDB	1QCY [ SRS ]    1QCY [ PdbSum ],   1QCY [ IMB ]   1QCY [ RSDB ]
HPRD	01892
	Protein Interaction databases
DIP	P56199
IntAct	P56199
	Polymorphism : SNP, mutations, diseases
OMIM	192968    [ map ]
GENECLINICS	192968
SNP	ITGA1 [dbSNP-NCBI]
SNP	NM_181501 [SNP-NCI]
SNP	ITGA1 [GeneSNPs - Utah]  ITGA1] [HGBASE - SRS]
HAPMAP	ITGA1 [HAPMAP]
COSMIC	ITGA1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ITGA1
	General knowledge
Family Browser	ITGA1 [UCSC Family Browser]
SOURCE	NM_181501
SMD	Hs.644352
SAGE	Hs.644352
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	receptor activity [Amigo]  receptor activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	collagen binding [Amigo]  collagen binding
GO	cell adhesion [Amigo]  cell adhesion
GO	cell-matrix adhesion [Amigo]  cell-matrix adhesion
GO	integrin-mediated signaling pathway [Amigo]  integrin-mediated signaling pathway
GO	integrin complex [Amigo]  integrin complex
GO	external side of plasma membrane [Amigo]  external side of plasma membrane
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	neutrophil chemotaxis [Amigo]  neutrophil chemotaxis
GO	cellular extravasation [Amigo]  cellular extravasation
PubGene	ITGA1
TreeFam	ITGA1
CTD	3672 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ITGA1 Related clones (RZPD - Berlin)
	PubMed
PubMed	69 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Sep 29 18:05:23 2008