ITGA10 (integrin subunit alpha 10)

2003-08-01  

Identity

HGNC
LOCATION
1q21.1
LOCUSID
ALIAS
PRO827
FUSION GENES

Other Information

Locus ID:

NCBI: 8515
MIM: 604042
HGNC: 6135
Ensembl: ENSG00000143127

Variants:

dbSNP: 8515
ClinVar: 8515
TCGA: ENSG00000143127
COSMIC: ITGA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143127ENST00000369304O75578
ENSG00000143127ENST00000539363O75578

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Regulation of actin cytoskeletonKEGGko04810
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
Regulation of actin cytoskeletonKEGGhsa04810
Hypertrophic cardiomyopathy (HCM)KEGGko05410
Hypertrophic cardiomyopathy (HCM)KEGGhsa05410
Arrhythmogenic right ventricular cardiomyopathy (ARVC)KEGGko05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC)KEGGhsa05412
Dilated cardiomyopathyKEGGko05414
Dilated cardiomyopathyKEGGhsa05414
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
HemostasisREACTOMER-HSA-109582
Platelet Adhesion to exposed collagenREACTOMER-HSA-75892
Extracellular matrix organizationREACTOMER-HSA-1474244
Integrin cell surface interactionsREACTOMER-HSA-216083
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
L1CAM interactionsREACTOMER-HSA-373760
CHL1 interactionsREACTOMER-HSA-447041

References

Pubmed IDYearTitleCitations
166845052006Regulation of integrin alpha10 expression in chondrocytes by the transcription factors AP-2epsilon and Ets-1.8
288545632017Integrin alpha 10, CD44, PTEN, cadherin-11 and lactoferrin expressions are potential biomarkers for selecting patients in need of central nervous system prophylaxis in diffuse large B-cell lymphoma.6
117312732001Characterization of the mouse integrin subunit alpha10 gene and comparison with its human homologue. Genomic structure, chromosomal localization and identification of splice variants.2
275692732017Unique charge-dependent constraint on collagen recognition by integrin α10β1.2

Citation

Dessen P

ITGA10 (integrin subunit alpha 10)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/41000/itga10