ITGA2 (integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor))

Identity

Other names	BR
	CD49B
	GPIa
	VLA-2
	VLAA2
HGNC	ITGA2
Location	5q11.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ITGA2   6137
Entrez_Gene	ITGA2  3673  integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
	Cards
GeneCards	ITGA2
Ensembl	ITGA2 [Search_View]   ENSG00000164171 [Gene_View]
Genatlas	ITGA2
GeneLynx	ITGA2
eGenome	ITGA2
euGene	3673
	Genomic and cartography
GoldenPath	ITGA2  -  5q11.2   chr5:52320913-52426366 +  5q11.2   [Description]    (hg18-March_2006)
Ensembl	ITGA2 - 5q11.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ITGA2
	Gene and transcription
Genbank	AK307952 [ ENTREZ ]
Genbank	AU126174 [ ENTREZ ]
Genbank	BC148596 [ ENTREZ ]
Genbank	BC156715 [ ENTREZ ]
Genbank	BE048389 [ ENTREZ ]
RefSeq	NM_002203 [ SRS ]    NM_002203 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NG_008330 [ SRS ]    NG_008330 [ ENTREZ ]
RefSeq	NT_006713 [ SRS ]    NT_006713 [ ENTREZ ]
RefSeq	NW_001838934 [ SRS ]    NW_001838934 [ ENTREZ ]
RefSeq	NW_922607 [ SRS ]    NW_922607 [ ENTREZ ]
AceView	ITGA2 AceView - NCBI
Unigene	Hs.482077 [ SRS ]    Hs.482077 [ NCBI ]     HS482077 [ spliceNest ]
Fast-db	3825 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P17301 [ SRS]    P17301 [ EXPASY ]     P17301 [ INTERPRO ]     P17301 [ UNIPROT ]
Prosite	PS00242 INTEGRIN_ALPHA [ SRS ]    PS00242 INTEGRIN_ALPHA [ Expasy ]
Prosite	PS50234 VWFA [ SRS ]    PS50234 VWFA [ Expasy ]
Interpro	IPR013517 FG-GAP [ SRS ]    IPR013517 FG-GAP [ EBI ]
Interpro	IPR013519 Int_alpha_beta-p [ SRS ]    IPR013519 Int_alpha_beta-p [ EBI ]
Interpro	IPR000413 Integrin_alpha [ SRS ]    IPR000413 Integrin_alpha [ EBI ]
Interpro	IPR013649 Integrin_alpha-2 [ SRS ]    IPR013649 Integrin_alpha-2 [ EBI ]
Interpro	IPR013513 Integrin_alpha_C [ SRS ]    IPR013513 Integrin_alpha_C [ EBI ]
Interpro	IPR002035 VWF_A [ SRS ]    IPR002035 VWF_A [ EBI ]
CluSTr	P17301
Pfam	PF01839 FG-GAP [ SRS ]    PF01839 FG-GAP [ Sanger ]    pfam01839 [ NCBI-CDD ]
Pfam	PF00357 Integrin_alpha [ SRS ]    PF00357 Integrin_alpha [ Sanger ]    pfam00357 [ NCBI-CDD ]
Pfam	PF08441 Integrin_alpha2 [ SRS ]    PF08441 Integrin_alpha2 [ Sanger ]    pfam08441 [ NCBI-CDD ]
Pfam	PF00092 VWA [ SRS ]    PF00092 VWA [ Sanger ]    pfam00092 [ NCBI-CDD ]
Smart	SM00191 Int_alpha [EMBL]
Smart	SM00327 VWA [EMBL]
Blocks	P17301
PDB	1AOX [ SRS ]    1AOX [ PdbSum ],   1AOX [ IMB ]   1AOX [ RSDB ]
PDB	1DZI [ SRS ]    1DZI [ PdbSum ],   1DZI [ IMB ]   1DZI [ RSDB ]
PDB	1PQB [ SRS ]    1PQB [ PdbSum ],   1PQB [ IMB ]   1PQB [ RSDB ]
PDB	1V7P [ SRS ]    1V7P [ PdbSum ],   1V7P [ IMB ]   1V7P [ RSDB ]
HPRD	01893
	Protein Interaction databases
DIP	P17301
IntAct	P17301
	Polymorphism : SNP, mutations, diseases
OMIM	192974    [ map ]
GENECLINICS	192974
SNP	ITGA2 [dbSNP-NCBI]
SNP	NM_002203 [SNP-NCI]
SNP	ITGA2 [GeneSNPs - Utah]  ITGA2] [HGBASE - SRS]
HAPMAP	ITGA2 [HAPMAP]
COSMIC	ITGA2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ITGA2
	General knowledge
Family Browser	ITGA2 [UCSC Family Browser]
SOURCE	NM_002203
SMD	Hs.482077
SAGE	Hs.482077
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	receptor activity [Amigo]  receptor activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	collagen binding [Amigo]  collagen binding
GO	plasma membrane [Amigo]  plasma membrane
GO	plasma membrane [Amigo]  plasma membrane
GO	cell adhesion [Amigo]  cell adhesion
GO	cell-matrix adhesion [Amigo]  cell-matrix adhesion
GO	integrin-mediated signaling pathway [Amigo]  integrin-mediated signaling pathway
GO	blood coagulation [Amigo]  blood coagulation
GO	integrin complex [Amigo]  integrin complex
GO	organ morphogenesis [Amigo]  organ morphogenesis
GO	external side of plasma membrane [Amigo]  external side of plasma membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	identical protein binding [Amigo]  identical protein binding
KEGG	Focal adhesion
KEGG	ECM-receptor interaction
KEGG	Hematopoietic cell lineage
KEGG	Regulation of actin cytoskeleton
PubGene	ITGA2
TreeFam	ITGA2
CTD	3673 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ITGA2 Related clones (RZPD - Berlin)
	PubMed
PubMed	201 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:16:30 2008