ITSN1 (intersectin 1 (SH3 domain protein))

Identity

Other names	ITSN
	MGC134948
	MGC134949
	SH3D1A
	SH3P17
HGNC	ITSN1
Location	21q22.1-q22.2
Location_base_pair	Starts at 33936654 and ends at 34132672 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ITSN1   6183
Entrez_Gene	ITSN1  6453  intersectin 1 (SH3 domain protein)
	Cards
GeneCards	ITSN1
Ensembl	ENSG00000205726 [Gene_View]  ITSN1 [Vega]
Genatlas	ITSN1
	Genomic and cartography
GoldenPath	ITSN1  -     chr21:33936654-34132672 +  21q22.11   [Description]    (hg18-March_2006)
Ensembl	ITSN1 - 21q22.11 [CytoView]
NCBI	Mapview
OMIM	602442 Disease map [OMIM]
HomoloGene	ITSN1
	Gene and transcription
Genbank	AF064243 [ ENTREZ ]
Genbank	AF064244 [ ENTREZ ]
Genbank	AF085873 [ ENTREZ ]
Genbank	AF114487 [ ENTREZ ]
Genbank	AF114488 [ ENTREZ ]
RefSeq	NM_001001132 [ SRS ]    NM_001001132 [ ENTREZ ]
RefSeq	NM_003024 [ SRS ]    NM_003024 [ ENTREZ ]
RefSeq	AC_000064 [ SRS ]    AC_000064 [ ENTREZ ]
RefSeq	AC_000153 [ SRS ]    AC_000153 [ ENTREZ ]
RefSeq	NC_000021 [ SRS ]    NC_000021 [ ENTREZ ]
RefSeq	NT_011512 [ SRS ]    NT_011512 [ ENTREZ ]
RefSeq	NW_001838706 [ SRS ]    NW_001838706 [ ENTREZ ]
RefSeq	NW_927384 [ SRS ]    NW_927384 [ ENTREZ ]
CCDS	ITSN1 CCDS - NCBI
AceView	ITSN1 AceView - NCBI
Unigene	Hs.160324 [ SRS ]    Hs.160324 [ NCBI ]
	Protein : pattern, domain, 3D structure
SwissProt	Q0PW94 [ SRS]    Q0PW94 [ EXPASY ]     Q0PW94 [ INTERPRO ]     Q0PW94 [ UNIPROT ] Q0PW94 [ VarSplice FASTA ]
Prosite	PS00018 EF_HAND_1 [ SRS ]    PS00018 EF_HAND_1 [ Expasy ]
Prosite	PS50222 EF_HAND_2 [ SRS ]    PS50222 EF_HAND_2 [ Expasy ]
Prosite	PS50031 EH [ SRS ]    PS50031 EH [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR011992 EF-Hand_type [ SRS ]    IPR011992 EF-Hand_type [ EBI ]
Interpro	IPR002048 EF_hand_Ca_bd [ SRS ]    IPR002048 EF_hand_Ca_bd [ EBI ]
Interpro	IPR000261 EPS15_homology [ SRS ]    IPR000261 EPS15_homology [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
Interpro	IPR013315 Spectrin_alpha [ SRS ]    IPR013315 Spectrin_alpha [ EBI ]
CluSTr	Q0PW94
Pfam	PF00036 efhand [ SRS ]    PF00036 efhand [ Sanger ]    pfam00036 [ NCBI-CDD ]
Pfam	PF00018 SH3_1 [ SRS ]    PF00018 SH3_1 [ Sanger ]    pfam00018 [ NCBI-CDD ]
Smart	SM00054 EFh [EMBL]
Smart	SM00027 EH [EMBL]
Smart	SM00326 SH3 [EMBL]
Prodom	PD000066 SH3[INRA-Toulouse]
Prodom	Q0PW94 Q0PW94_HUMAN [ Domain structure ]   Q0PW94 Q0PW94_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q0PW94
HPRD	03898
	Protein Interaction databases
DIP	Q0PW94
IntAct	Q0PW94
	Polymorphism : SNP, mutations, diseases
OMIM	602442    [ map ]
GENETests	602442
SNP	ITSN1 [dbSNP-NCBI]
SNP	NM_001001132 [SNP-NCI]
SNP	NM_003024 [SNP-NCI]
SNP	ITSN1 [GeneSNPs - Utah]  ITSN1] [HGBASE - SRS]
HAPMAP	ITSN1 [HAPMAP]
HGMD	ITSN1
Genetic Association	ITSN1
CDC HuGE	ITSN1
	General knowledge
Family Browser	ITSN1 [UCSC Family Browser]
SOURCE	NM_001001132
SOURCE	NM_003024
SMD	Hs.160324
SAGE	Hs.160324
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	Rho guanyl-nucleotide exchange factor activity [Amigo]  Rho guanyl-nucleotide exchange factor activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	endomembrane system [Amigo]  endomembrane system
GO	membrane [Amigo]  membrane
GO	synaptosome [Amigo]  synaptosome
GO	cell junction [Amigo]  cell junction
GO	regulation of Rho protein signal transduction [Amigo]  regulation of Rho protein signal transduction
GO	cell projection [Amigo]  cell projection
GO	synapse [Amigo]  synapse
GO	synaptic vesicle endocytosis [Amigo]  synaptic vesicle endocytosis
PubGene	ITSN1
TreeFam	ITSN1
CTD	6453 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ITSN1 Related clones (RZPD - Berlin)
	PubMed
PubMed	36 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 16:53:06 2008