Atlas of Genetics and Cytogenetics in Oncology and Haematology

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LHX4 (LIM homeobox 4)

Identity

Other namesCPHD4
Gsh-4
Gsh4
HGNC (Hugo) LHX4
Location 1q25.2
Location_base_pair Starts at 178466065 and ends at 178510811 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LHX4   21734
Entrez_Gene (NCBI)LHX4  89884  LIM homeobox 4
Cards
GeneCards (Weizmann)LHX4
Ensembl (Hinxton)ENSG00000121454 [Gene_View]  LHX4 [Vega]
AceView (NCBI)LHX4
Genatlas (Paris)LHX4
euGene (Indiana)89884
SOURCE (Stanford)NM_033343
Gene Expression (Array Express) ENSG00000121454
Genomic and cartography
GoldenPath (UCSC)LHX4  -  1q25.2   chr1:178466065-178510811 +  1q25.2   [Description]    (hg18-March_2006)
EnsemblLHX4 - 1q25.2 [CytoView]
Mapping of homologs : NCBILHX4 [Mapview]
OMIM262700   602146   606606   
Gene and transcription
Gene : Genbank (Entrez)AB037683 AB055703 AB055704 AF179849 AF282899
Reference sequence (RefSeq transcript) :SRSNM_033343
Reference transcript : EntrezNM_033343
RefSeq genomic : SRSAC_000044 AC_000133 NC_000001 NG_008081 NT_004487 NW_001838533 NW_926128
RefSeq genomic : EntrezAC_000044 AC_000133 NC_000001 NG_008081 NT_004487 NW_001838533 NW_926128
Consensus coding sequences : CCDS NCBILHX4
Cluster EST : UnigeneHs.658487 [ SRS ] Hs.658487 [ NCBI ]
Alternative Splicing : Fast-db (Paris)17618
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ969G2 (SRS) Q969G2 (Expasy) Q969G2 (Uniprot)
With graphics : InterProQ969G2
Splice isoforms : VarSplice FASTAQ969G2(VarSplice FASTA)
Domaine pattern : Prosite (SRS)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domain pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (SRS)Homeobox    Homeobox_CS    Homeodomain-like    Homeodomain-rel    Znf_LIM   
Domains : Interpro (EBI)Homeobox    Homeobox_CS    Homeodomain-like    Homeodomain-rel    Znf_LIM   
Related proteins : CluSTrQ969G2
Domain families : Pfam SRSHomeobox (PF00046)    LIM (PF00412)   
Domain families : Pfam SangerHomeobox (PF00046)    LIM (PF00412)   
Domain families : Pfam NCBIpfam00046    pfam00412   
Domain families : Smart EMBLHOX (SM00389)  LIM (SM00132)  
Blocks (Seattle)Q969G2
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD03686
Protein Interaction databases
DIP (DOE-UCLA)Q969G2
IntAct (EBI)Q969G2
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBILHX4
SNP : GeneSNP UtahLHX4
SNP : HGBaseLHX4
Genetic variants : HAPMAPLHX4
Somatic Mutations in Cancer : COSMICLHX4 
Translocation Breakpoints in Cancer : TICdbtranscription 
Mutations and Diseases : HGMDLHX4
Hereditary diseases : OMIM262700    602146    606606   
Hereditary diseases : GENETests262700    602146    606606   
Diseases : Genetic AssociationLHX4
General knowledge
Homologs : HomoloGeneLHX4
Homology/Alignments : Family Browser UCSCLHX4
Phylogenetic Trees/Animal Genes : TreeFamLHX4
Chemical/Protein Interactions : CTD89884
Keywords Ontology : AmiGOtranscription factor activity  nucleus  regulation of transcription, DNA-dependent  anti-apoptosis  motor axon guidance  zinc ion binding  organ morphogenesis  medial motor column neuron differentiation  sequence-specific DNA binding  metal ion binding  
Keywords Ontology : EGO-EBItranscription factor activity  nucleus  regulation of transcription, DNA-dependent  anti-apoptosis  motor axon guidance  zinc ion binding  organ morphogenesis  medial motor column neuron differentiation  sequence-specific DNA binding  metal ion binding  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesLHX4 Related clones (RZPD - Berlin)
Literature
PubMed13 Pubmed reference(s) in Entrez
PubGeneLHX4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:42:10 CET 2010
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