LIFR (leukemia inhibitory factor receptor alpha)

Identity

Other names	CD118
	FLJ98106
	FLJ99923
	LIF-R
	SJS2
	STWS
	SWS
HGNC	LIFR
Location	5p13-p12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	LIFR   6597
Entrez_Gene	LIFR  3977  leukemia inhibitory factor receptor alpha
	Cards
GeneCards	LIFR
Ensembl	LIFR [Search_View]   ENSG00000113594 [Gene_View]
Genatlas	LIFR
GeneLynx	LIFR
eGenome	LIFR
euGene	3977
	Genomic and cartography
GoldenPath	LIFR  -     chr5:38510822-38592505 -  5p13.1   [Description]    (hg18-March_2006)
Ensembl	LIFR - 5p13.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	LIFR
	Gene and transcription
Genbank	AK290059 [ ENTREZ ]
Genbank	AK308158 [ ENTREZ ]
Genbank	AK309882 [ ENTREZ ]
Genbank	BC141428 [ ENTREZ ]
Genbank	BC153096 [ ENTREZ ]
RefSeq	NM_001127671 [ SRS ]    NM_001127671 [ ENTREZ ]
RefSeq	NM_002310 [ SRS ]    NM_002310 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_006576 [ SRS ]    NT_006576 [ ENTREZ ]
RefSeq	NW_001838933 [ SRS ]    NW_001838933 [ ENTREZ ]
RefSeq	NW_922596 [ SRS ]    NW_922596 [ ENTREZ ]
AceView	LIFR AceView - NCBI
Unigene	Hs.133421 [ SRS ]    Hs.133421 [ NCBI ]     HS133421 [ spliceNest ]
Fast-db	3042 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P42702 [ SRS]    P42702 [ EXPASY ]     P42702 [ INTERPRO ]     P42702 [ UNIPROT ]
Prosite	PS50853 FN3 [ SRS ]    PS50853 FN3 [ Expasy ]
Prosite	PS01353 HEMATOPO_REC_L_F2 [ SRS ]    PS01353 HEMATOPO_REC_L_F2 [ Expasy ]
Interpro	IPR008957 Fibronectin_typ-III-like_fold [ SRS ]    IPR008957 Fibronectin_typ-III-like_fold [ EBI ]
Interpro	IPR003961 FN_III [ SRS ]    IPR003961 FN_III [ EBI ]
Interpro	IPR003529 Hematopoietin_rcpt_gp130_CS [ SRS ]    IPR003529 Hematopoietin_rcpt_gp130_CS [ EBI ]
CluSTr	P42702
Pfam	PF00041 fn3 [ SRS ]    PF00041 fn3 [ Sanger ]    pfam00041 [ NCBI-CDD ]
Smart	SM00060 FN3 [EMBL]
Blocks	P42702
HPRD	01048
	Protein Interaction databases
DIP	P42702
IntAct	P42702
	Polymorphism : SNP, mutations, diseases
OMIM	151443;601559    [ map ]
GENECLINICS	151443;601559
SNP	LIFR [dbSNP-NCBI]
SNP	NM_001127671 [SNP-NCI]
SNP	NM_002310 [SNP-NCI]
SNP	LIFR [GeneSNPs - Utah]  LIFR] [HGBASE - SRS]
HAPMAP	LIFR [HAPMAP]
COSMIC	LIFR [Somatic mutation (COSMIC-CGP-Sanger)]
TICdb	receptor [Translocation breakpoints In Cancer]
HGMD	LIFR
	General knowledge
Family Browser	LIFR [UCSC Family Browser]
SOURCE	NM_001127671
SOURCE	NM_002310
SMD	Hs.133421
SAGE	Hs.133421
GO	receptor activity [Amigo]  receptor activity
GO	leukemia inhibitory factor receptor activity [Amigo]  leukemia inhibitory factor receptor activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	positive regulation of cell proliferation [Amigo]  positive regulation of cell proliferation
GO	cytokine and chemokine mediated signaling pathway [Amigo]  cytokine and chemokine mediated signaling pathway
KEGG	Cytokine-cytokine receptor interaction
KEGG	Jak-STAT signaling pathway
PubGene	LIFR
TreeFam	LIFR
CTD	3977 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	LIFR Related clones (RZPD - Berlin)
	PubMed
PubMed	44 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:18:07 2008