LPL (lipoprotein lipase)

Identity

Other names	HDLCQ11
	LIPD
HGNC	LPL
Location	8p22
Location_base_pair	Starts at 19840862 and ends at 19869050 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	LPL   6677
Entrez_Gene	LPL  4023  lipoprotein lipase
	Cards
GeneCards	LPL
Ensembl	LPL [Search_View]   ENSG00000175445 [Gene_View]
Genatlas	LPL
GeneLynx	LPL
eGenome	LPL
euGene	4023
	Genomic and cartography
GoldenPath	LPL  -  8p22   chr8:19840862-19869050 +  8p21.3   [Description]    (hg18-March_2006)
Ensembl	LPL - 8p21.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	LPL
	Gene and transcription
Genbank	AK092286 [ ENTREZ ]
Genbank	AK222464 [ ENTREZ ]
Genbank	AK290290 [ ENTREZ ]
Genbank	AK312311 [ ENTREZ ]
Genbank	BC011353 [ ENTREZ ]
RefSeq	NM_000237 [ SRS ]    NM_000237 [ ENTREZ ]
RefSeq	AC_000051 [ SRS ]    AC_000051 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_030737 [ SRS ]    NT_030737 [ ENTREZ ]
RefSeq	NW_001839126 [ SRS ]    NW_001839126 [ ENTREZ ]
RefSeq	NW_923907 [ SRS ]    NW_923907 [ ENTREZ ]
AceView	LPL AceView - NCBI
Unigene	Hs.180878 [ SRS ]    Hs.180878 [ NCBI ]     HS180878 [ spliceNest ]
Fast-db	1906 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P06858 [ SRS]    P06858 [ EXPASY ]     P06858 [ INTERPRO ]     P06858 [ UNIPROT ]
Prosite	PS00120 LIPASE_SER [ SRS ]    PS00120 LIPASE_SER [ Expasy ]
Prosite	PS50095 PLAT [ SRS ]    PS50095 PLAT [ Expasy ]
Interpro	IPR000734 Lipase [ SRS ]    IPR000734 Lipase [ EBI ]
Interpro	IPR008262 Lipase_AS [ SRS ]    IPR008262 Lipase_AS [ EBI ]
Interpro	IPR013818 Lipase_N [ SRS ]    IPR013818 Lipase_N [ EBI ]
Interpro	IPR002330 Lipo_Lipase [ SRS ]    IPR002330 Lipo_Lipase [ EBI ]
Interpro	IPR001024 LipOase_LH2 [ SRS ]    IPR001024 LipOase_LH2 [ EBI ]
Interpro	IPR016272 Lipoprotein_lipase_LIPH [ SRS ]    IPR016272 Lipoprotein_lipase_LIPH [ EBI ]
CluSTr	P06858
Pfam	PF00151 Lipase [ SRS ]    PF00151 Lipase [ Sanger ]    pfam00151 [ NCBI-CDD ]
Pfam	PF01477 PLAT [ SRS ]    PF01477 PLAT [ Sanger ]    pfam01477 [ NCBI-CDD ]
Smart	SM00308 LH2 [EMBL]
Blocks	P06858
HPRD	01999
	Protein Interaction databases
DIP	P06858
IntAct	P06858
	Polymorphism : SNP, mutations, diseases
OMIM	144250;238600;609708    [ map ]
GENECLINICS	144250;238600;609708
SNP	LPL [dbSNP-NCBI]
SNP	NM_000237 [SNP-NCI]
SNP	LPL [GeneSNPs - Utah]  LPL] [HGBASE - SRS]
HAPMAP	LPL [HAPMAP]
HGMD	LPL
	General knowledge
Family Browser	LPL [UCSC Family Browser]
SOURCE	NM_000237
SMD	Hs.180878
SAGE	Hs.180878
Enzyme	3.1.1.34 [ Enzyme-Expasy ]   3.1.1.34 [ Enzyme-SRS ]   3.1.1.34 [ IntEnz-EBI ]   3.1.1.34 [ BRENDA ]   3.1.1.34 [ KEGG ]   3.1.1.34 [ WIT ]
GO	lipoprotein lipase activity [Amigo]  lipoprotein lipase activity
GO	phospholipase activity [Amigo]  phospholipase activity
GO	triacylglycerol lipase activity [Amigo]  triacylglycerol lipase activity
GO	receptor binding [Amigo]  receptor binding
GO	lipid transporter activity [Amigo]  lipid transporter activity
GO	extracellular region [Amigo]  extracellular region
GO	plasma membrane [Amigo]  plasma membrane
GO	triacylglycerol metabolic process [Amigo]  triacylglycerol metabolic process
GO	phospholipid metabolic process [Amigo]  phospholipid metabolic process
GO	blood circulation [Amigo]  blood circulation
GO	heparin binding [Amigo]  heparin binding
GO	lipid catabolic process [Amigo]  lipid catabolic process
GO	hydrolase activity [Amigo]  hydrolase activity
GO	anchored to membrane [Amigo]  anchored to membrane
GO	chylomicron [Amigo]  chylomicron
BIOCARTA	Low-density lipoprotein (LDL) pathway during atherogenesis    [Genes]
BIOCARTA	Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)    [Genes]
BIOCARTA	Role of PPAR-gamma Coactivators in Obesity and Thermogenesis    [Genes]
BIOCARTA	Visceral Fat Deposits and the Metabolic Syndrome    [Genes]
KEGG	Glycerolipid metabolism
KEGG	PPAR signaling pathway
KEGG	Alzheimer's disease
PubGene	LPL
TreeFam	LPL
CTD	4023 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	LPL Related clones (RZPD - Berlin)
	PubMed
PubMed	355 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:48:51 2008