LTK (leukocyte receptor tyrosine kinase)

Identity

Other names	TYK1
Hugo	LTK
Location	15q15.1-q21.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	LTK
GDB	LTK
Entrez_Gene	LTK  4058  leukocyte receptor tyrosine kinase
	Cards
GeneCards	LTK
Ensembl	LTK [Search_View]   ENSG00000062524 [Gene_View]
Genatlas	LTK
GeneLynx	LTK
eGenome	LTK
euGene	4058
	Genomic and cartography
GoldenPath	LTK  -     chr15:39583132-39593369 -  15q15.1   [Description]    (hg18-March_2006)
Ensembl	LTK - 15q15.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	LTK
	Gene and transcription
Genbank	BC045607 [ ENTREZ ]
Genbank	BX329448 [ ENTREZ ]
Genbank	CA394397 [ ENTREZ ]
Genbank	CR611113 [ ENTREZ ]
Genbank	D16105 [ ENTREZ ]
RefSeq	NM_002344 [ SRS ]    NM_002344 [ ENTREZ ]
RefSeq	NM_206961 [ SRS ]    NM_206961 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_925840 [ SRS ]    NW_925840 [ ENTREZ ]
AceView	LTK AceView - NCBI
Unigene	Hs.434481 [ SRS ]    Hs.434481 [ NCBI ]     HS434481 [ spliceNest ]
Fast-db	2590 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P29376 [ SRS]    P29376 [ EXPASY ]     P29376 [ INTERPRO ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00109 PROTEIN_KINASE_TYR [ SRS ]    PS00109 PROTEIN_KINASE_TYR [ Expasy ]
Prosite	PS00239 RECEPTOR_TYR_KIN_II [ SRS ]    PS00239 RECEPTOR_TYR_KIN_II [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR002011 Recept_tyr_kinase-II_CS [ SRS ]    IPR002011 Recept_tyr_kinase-II_CS [ EBI ]
Interpro	IPR001245 Tyr_pkinase [ SRS ]    IPR001245 Tyr_pkinase [ EBI ]
Interpro	IPR008266 Tyr_pkinase_AS [ SRS ]    IPR008266 Tyr_pkinase_AS [ EBI ]
CluSTr	P29376
Pfam	PF07714 Pkinase_Tyr [ SRS ]    PF07714 Pkinase_Tyr [ Sanger ]    pfam07714 [ NCBI-CDD ]
Smart	SM00219 TyrKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P29376 LTK_HUMAN [ Domain structure ]   P29376 LTK_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P29376
HPRD	01052
	Protein Interaction databases
DIP	P29376
IntAct	P29376
	Polymorphism : SNP, mutations, diseases
OMIM	151520    [ map ]
GENECLINICS	151520
SNP	LTK [dbSNP-NCBI]
SNP	NM_002344 [SNP-NCI]
SNP	NM_206961 [SNP-NCI]
SNP	LTK [GeneSNPs - Utah]  LTK] [HGBASE - SRS]
HAPMAP	LTK [HAPMAP]
COSMIC	LTK [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	LTK
	General knowledge
Family Browser	LTK [UCSC Family Browser]
SOURCE	NM_002344
SOURCE	NM_206961
SMD	Hs.434481
SAGE	Hs.434481
Enzyme	2.7.10.1 [ Enzyme-SRS ]   2.7.10.1 [ Brenda-SRS ]   2.7.10.1 [ KEGG ]   2.7.10.1 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	transmembrane receptor protein tyrosine kinase activity [Amigo]  transmembrane receptor protein tyrosine kinase activity
GO	receptor activity [Amigo]  receptor activity
GO	ATP binding [Amigo]  ATP binding
GO	soluble fraction [Amigo]  soluble fraction
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	signal transduction [Amigo]  signal transduction
GO	transmembrane receptor protein tyrosine kinase signaling pathway [Amigo]  transmembrane receptor protein tyrosine kinase signaling pathway
GO	transferase activity [Amigo]  transferase activity
PubGene	LTK
TreeFam	LTK
CTD	4058 [Comparative Genomics Database]
	Other databases
	Probes
Probe	LTK Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:15:07 2008