MIR29B1 (microRNA 29b-1)

2010-05-01  

Identity

HGNC
MIR29B1
LOCATION
7q32.3
LOCUSID
407024
ALIAS
MIRN29B1,miR-29b,miRNA29B1,mir-29b-1

Other Information

Locus ID:

NCBI: 407024
MIM: 610783
HGNC: 31619
Ensembl: ENSG00000283797
miRBase:

Variants:

dbSNP: 407024
ClinVar: 407024
TCGA: ENSG00000283797
COSMIC: MIR29B1

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
184345502008Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression.400
192119352009MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.293
205642132010Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.122
231906082012miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1.69
227511192013Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4.57
248200272014Tumor-suppressive microRNA-29s inhibit cancer cell migration and invasion via targeting LAMC1 in prostate cancer.45
204799362010MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia.41
206283972010The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML.40
219518442011Overexpression of microRNA-29b induces apoptosis of multiple myeloma cells through down regulating Mcl-1.40
252774102015MicroRNA 29 targets nuclear factor-κB-repressing factor and Claudin 1 to increase intestinal permeability.40

Citation

Dessen P

MIR29B1 (microRNA 29b-1)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51471/mir29b1