MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase)

Identity

Other names	MGC129643
	MSR
HGNC	MTRR
Location	5p15.31
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	MTRR   7473
Entrez_Gene	MTRR  4552  5-methyltetrahydrofolate-homocysteine methyltransferase reductase
	Cards
GeneCards	MTRR
Ensembl	MTRR [Search_View]   ENSG00000124275 [Gene_View]
Genatlas	MTRR
GeneLynx	MTRR
eGenome	MTRR
euGene	4552
	Genomic and cartography
GoldenPath	MTRR  -  5p15.31   chr5:7922217-7954235 +  5p15.31   [Description]    (hg18-March_2006)
Ensembl	MTRR - 5p15.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	MTRR
	Gene and transcription
Genbank	AF025794 [ ENTREZ ]
Genbank	AF121214 [ ENTREZ ]
Genbank	AK308442 [ ENTREZ ]
Genbank	AK311663 [ ENTREZ ]
Genbank	BC035977 [ ENTREZ ]
RefSeq	NM_002454 [ SRS ]    NM_002454 [ ENTREZ ]
RefSeq	NM_024010 [ SRS ]    NM_024010 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_006576 [ SRS ]    NT_006576 [ ENTREZ ]
RefSeq	NW_001838927 [ SRS ]    NW_001838927 [ ENTREZ ]
RefSeq	NW_922518 [ SRS ]    NW_922518 [ ENTREZ ]
AceView	MTRR AceView - NCBI
Unigene	Hs.481551 [ SRS ]    Hs.481551 [ NCBI ]     HS481551 [ spliceNest ]
Fast-db	1349 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q7Z4M8 [ SRS]    Q7Z4M8 [ EXPASY ]     Q7Z4M8 [ INTERPRO ]     Q7Z4M8 [ UNIPROT ]
Prosite	PS50902 FLAVODOXIN_LIKE [ SRS ]    PS50902 FLAVODOXIN_LIKE [ Expasy ]
Interpro	IPR003097 FAD-binding_1 [ SRS ]    IPR003097 FAD-binding_1 [ EBI ]
Interpro	IPR001094 Flavdoxin_like [ SRS ]    IPR001094 Flavdoxin_like [ EBI ]
Interpro	IPR008254 Flavodoxin/NO_synth [ SRS ]    IPR008254 Flavodoxin/NO_synth [ EBI ]
Interpro	IPR001709 FPN_cyt_redctse [ SRS ]    IPR001709 FPN_cyt_redctse [ EBI ]
Interpro	IPR001433 OxRdtase_FAD/NAD_bd [ SRS ]    IPR001433 OxRdtase_FAD/NAD_bd [ EBI ]
CluSTr	Q7Z4M8
Pfam	PF00667 FAD_binding_1 [ SRS ]    PF00667 FAD_binding_1 [ Sanger ]    pfam00667 [ NCBI-CDD ]
Pfam	PF00258 Flavodoxin_1 [ SRS ]    PF00258 Flavodoxin_1 [ Sanger ]    pfam00258 [ NCBI-CDD ]
Pfam	PF00175 NAD_binding_1 [ SRS ]    PF00175 NAD_binding_1 [ Sanger ]    pfam00175 [ NCBI-CDD ]
Blocks	Q7Z4M8
HPRD	03979
	Protein Interaction databases
DIP	Q7Z4M8
IntAct	Q7Z4M8
	Polymorphism : SNP, mutations, diseases
OMIM	236270;601634;602568    [ map ]
GENECLINICS	236270;601634;602568
SNP	MTRR [dbSNP-NCBI]
SNP	NM_002454 [SNP-NCI]
SNP	NM_024010 [SNP-NCI]
SNP	MTRR [GeneSNPs - Utah]  MTRR] [HGBASE - SRS]
HAPMAP	MTRR [HAPMAP]
HGMD	MTRR
	General knowledge
Family Browser	MTRR [UCSC Family Browser]
SOURCE	NM_002454
SOURCE	NM_024010
SMD	Hs.481551
SAGE	Hs.481551
GO	iron ion binding [Amigo]  iron ion binding
GO	cytoplasm [Amigo]  cytoplasm
GO	mitochondrion [Amigo]  mitochondrion
GO	cytosol [Amigo]  cytosol
GO	methyltransferase activity [Amigo]  methyltransferase activity
GO	amino acid biosynthetic process [Amigo]  amino acid biosynthetic process
GO	electron carrier activity [Amigo]  electron carrier activity
GO	methionine biosynthetic process [Amigo]  methionine biosynthetic process
GO	FMN binding [Amigo]  FMN binding
GO	FMN binding [Amigo]  FMN binding
GO	oxidoreductase activity [Amigo]  oxidoreductase activity
GO	transferase activity [Amigo]  transferase activity
GO	[methionine synthase] reductase activity [Amigo]  [methionine synthase] reductase activity
GO	FAD binding [Amigo]  FAD binding
GO	NADP binding [Amigo]  NADP binding
GO	oxidation reduction [Amigo]  oxidation reduction
PubGene	MTRR
TreeFam	MTRR
CTD	4552 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	MTRR Related clones (RZPD - Berlin)
	PubMed
PubMed	127 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:21:04 2008