NCOA1 (nuclear receptor coactivator 1)

Identity

Other names	F-SRC-1
	KAT13A
	MGC129719
	MGC129720
	NCoA-1
	RIP160
	SRC-1
	SRC1
HGNC	NCOA1
Location	2p23
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	NCOA1   7668
Entrez_Gene	NCOA1  8648  nuclear receptor coactivator 1
	Cards
GeneCards	NCOA1
Ensembl	NCOA1 [Search_View]   ENSG00000084676 [Gene_View]
Genatlas	NCOA1
GeneLynx	NCOA1
eGenome	NCOA1
euGene	8648
	Genomic and cartography
GoldenPath	NCOA1  -  2p23   chr2:24660850-24847074 +  2p23.3   [Description]    (hg18-March_2006)
Ensembl	NCOA1 - 2p23.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	NCOA1
	Gene and transcription
Genbank	AJ000881 [ ENTREZ ]
Genbank	AJ000882 [ ENTREZ ]
Genbank	AK226063 [ ENTREZ ]
Genbank	AK290019 [ ENTREZ ]
Genbank	BC035976 [ ENTREZ ]
RefSeq	NM_003743 [ SRS ]    NM_003743 [ ENTREZ ]
RefSeq	NM_147223 [ SRS ]    NM_147223 [ ENTREZ ]
RefSeq	NM_147233 [ SRS ]    NM_147233 [ ENTREZ ]
RefSeq	AC_000045 [ SRS ]    AC_000045 [ ENTREZ ]
RefSeq	AC_000134 [ SRS ]    AC_000134 [ ENTREZ ]
RefSeq	NC_000002 [ SRS ]    NC_000002 [ ENTREZ ]
RefSeq	NT_022184 [ SRS ]    NT_022184 [ ENTREZ ]
RefSeq	NW_001838768 [ SRS ]    NW_001838768 [ ENTREZ ]
RefSeq	NW_927719 [ SRS ]    NW_927719 [ ENTREZ ]
AceView	NCOA1 AceView - NCBI
Unigene	Hs.709209 [ SRS ]    Hs.709209 [ NCBI ]     HS709209 [ spliceNest ]
Fast-db	2139 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q15788 [ SRS]    Q15788 [ EXPASY ]     Q15788 [ INTERPRO ]     Q15788 [ UNIPROT ]
Prosite	PS50888 HLH [ SRS ]    PS50888 HLH [ Expasy ]
Prosite	PS50112 PAS [ SRS ]    PS50112 PAS [ Expasy ]
Interpro	IPR010011 DUF1518 [ SRS ]    IPR010011 DUF1518 [ EBI ]
Interpro	IPR001092 HLH_basic [ SRS ]    IPR001092 HLH_basic [ EBI ]
Interpro	IPR011598 HLH_DNA_bd [ SRS ]    IPR011598 HLH_DNA_bd [ EBI ]
Interpro	IPR014920 Nuc_rcpt_coact_Ncoa-typ [ SRS ]    IPR014920 Nuc_rcpt_coact_Ncoa-typ [ EBI ]
Interpro	IPR017426 Nuclear_rcpt_coactivator [ SRS ]    IPR017426 Nuclear_rcpt_coactivator [ EBI ]
Interpro	IPR000014 PAS [ SRS ]    IPR000014 PAS [ EBI ]
Interpro	IPR013767 PAS_fold [ SRS ]    IPR013767 PAS_fold [ EBI ]
Interpro	IPR014935 SRC-1 [ SRS ]    IPR014935 SRC-1 [ EBI ]
Interpro	IPR008955 Src1_rcpt_coact [ SRS ]    IPR008955 Src1_rcpt_coact [ EBI ]
CluSTr	Q15788
Pfam	PF07469 DUF1518 [ SRS ]    PF07469 DUF1518 [ Sanger ]    pfam07469 [ NCBI-CDD ]
Pfam	PF00010 HLH [ SRS ]    PF00010 HLH [ Sanger ]    pfam00010 [ NCBI-CDD ]
Pfam	PF08815 Nuc_rec_co-act [ SRS ]    PF08815 Nuc_rec_co-act [ Sanger ]    pfam08815 [ NCBI-CDD ]
Pfam	PF00989 PAS [ SRS ]    PF00989 PAS [ Sanger ]    pfam00989 [ NCBI-CDD ]
Pfam	PF08832 SRC-1 [ SRS ]    PF08832 SRC-1 [ Sanger ]    pfam08832 [ NCBI-CDD ]
Smart	SM00353 HLH [EMBL]
Smart	SM00091 PAS [EMBL]
Blocks	Q15788
PDB	1FM6 [ SRS ]    1FM6 [ PdbSum ],   1FM6 [ IMB ]   1FM6 [ RSDB ]
PDB	1FM9 [ SRS ]    1FM9 [ PdbSum ],   1FM9 [ IMB ]   1FM9 [ RSDB ]
PDB	1K4W [ SRS ]    1K4W [ PdbSum ],   1K4W [ IMB ]   1K4W [ RSDB ]
PDB	1K74 [ SRS ]    1K74 [ PdbSum ],   1K74 [ IMB ]   1K74 [ RSDB ]
PDB	1K7L [ SRS ]    1K7L [ PdbSum ],   1K7L [ IMB ]   1K7L [ RSDB ]
PDB	1KV6 [ SRS ]    1KV6 [ PdbSum ],   1KV6 [ IMB ]   1KV6 [ RSDB ]
PDB	1N4H [ SRS ]    1N4H [ PdbSum ],   1N4H [ IMB ]   1N4H [ RSDB ]
PDB	1NQ7 [ SRS ]    1NQ7 [ PdbSum ],   1NQ7 [ IMB ]   1NQ7 [ RSDB ]
PDB	1NRL [ SRS ]    1NRL [ PdbSum ],   1NRL [ IMB ]   1NRL [ RSDB ]
PDB	1P8D [ SRS ]    1P8D [ PdbSum ],   1P8D [ IMB ]   1P8D [ RSDB ]
PDB	1PZL [ SRS ]    1PZL [ PdbSum ],   1PZL [ IMB ]   1PZL [ RSDB ]
PDB	1RDT [ SRS ]    1RDT [ PdbSum ],   1RDT [ IMB ]   1RDT [ RSDB ]
PDB	1TFC [ SRS ]    1TFC [ PdbSum ],   1TFC [ IMB ]   1TFC [ RSDB ]
PDB	1U3R [ SRS ]    1U3R [ PdbSum ],   1U3R [ IMB ]   1U3R [ RSDB ]
PDB	1U3S [ SRS ]    1U3S [ PdbSum ],   1U3S [ IMB ]   1U3S [ RSDB ]
PDB	1X76 [ SRS ]    1X76 [ PdbSum ],   1X76 [ IMB ]   1X76 [ RSDB ]
PDB	1X78 [ SRS ]    1X78 [ PdbSum ],   1X78 [ IMB ]   1X78 [ RSDB ]
PDB	1X7B [ SRS ]    1X7B [ PdbSum ],   1X7B [ IMB ]   1X7B [ RSDB ]
PDB	1X7J [ SRS ]    1X7J [ PdbSum ],   1X7J [ IMB ]   1X7J [ RSDB ]
PDB	1XIU [ SRS ]    1XIU [ PdbSum ],   1XIU [ IMB ]   1XIU [ RSDB ]
PDB	1XV9 [ SRS ]    1XV9 [ PdbSum ],   1XV9 [ IMB ]   1XV9 [ RSDB ]
PDB	1XVP [ SRS ]    1XVP [ PdbSum ],   1XVP [ IMB ]   1XVP [ RSDB ]
PDB	1YY4 [ SRS ]    1YY4 [ PdbSum ],   1YY4 [ IMB ]   1YY4 [ RSDB ]
PDB	1YYE [ SRS ]    1YYE [ PdbSum ],   1YYE [ IMB ]   1YYE [ RSDB ]
PDB	1ZAF [ SRS ]    1ZAF [ PdbSum ],   1ZAF [ IMB ]   1ZAF [ RSDB ]
PDB	2A3I [ SRS ]    2A3I [ PdbSum ],   2A3I [ IMB ]   2A3I [ RSDB ]
PDB	2C52 [ SRS ]    2C52 [ PdbSum ],   2C52 [ IMB ]   2C52 [ RSDB ]
PDB	2FVJ [ SRS ]    2FVJ [ PdbSum ],   2FVJ [ IMB ]   2FVJ [ RSDB ]
PDB	2GTK [ SRS ]    2GTK [ PdbSum ],   2GTK [ IMB ]   2GTK [ RSDB ]
PDB	2HBH [ SRS ]    2HBH [ PdbSum ],   2HBH [ IMB ]   2HBH [ RSDB ]
PDB	2HC4 [ SRS ]    2HC4 [ PdbSum ],   2HC4 [ IMB ]   2HC4 [ RSDB ]
PDB	2HCD [ SRS ]    2HCD [ PdbSum ],   2HCD [ IMB ]   2HCD [ RSDB ]
PDB	2HFP [ SRS ]    2HFP [ PdbSum ],   2HFP [ IMB ]   2HFP [ RSDB ]
PDB	2P54 [ SRS ]    2P54 [ PdbSum ],   2P54 [ IMB ]   2P54 [ RSDB ]
PDB	2PRG [ SRS ]    2PRG [ PdbSum ],   2PRG [ IMB ]   2PRG [ RSDB ]
PDB	3BQD [ SRS ]    3BQD [ PdbSum ],   3BQD [ IMB ]   3BQD [ RSDB ]
HPRD	04070
	Protein Interaction databases
DIP	Q15788
IntAct	Q15788
	Polymorphism : SNP, mutations, diseases
OMIM	602691    [ map ]
GENECLINICS	602691
SNP	NCOA1 [dbSNP-NCBI]
SNP	NM_003743 [SNP-NCI]
SNP	NM_147223 [SNP-NCI]
SNP	NM_147233 [SNP-NCI]
SNP	NCOA1 [GeneSNPs - Utah]  NCOA1] [HGBASE - SRS]
HAPMAP	NCOA1 [HAPMAP]
COSMIC	NCOA1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	NCOA1
	General knowledge
Family Browser	NCOA1 [UCSC Family Browser]
SOURCE	NM_003743
SOURCE	NM_147223
SOURCE	NM_147233
SMD	Hs.709209
SAGE	Hs.709209
Enzyme	2.3.1.48 [ Enzyme-Expasy ]   2.3.1.48 [ Enzyme-SRS ]   2.3.1.48 [ IntEnz-EBI ]   2.3.1.48 [ BRENDA ]   2.3.1.48 [ KEGG ]   2.3.1.48 [ WIT ]
GO	transcription coactivator activity [Amigo]  transcription coactivator activity
GO	histone acetyltransferase activity [Amigo]  histone acetyltransferase activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	nucleus [Amigo]  nucleus
GO	signal transduction [Amigo]  signal transduction
GO	acyltransferase activity [Amigo]  acyltransferase activity
GO	transferase activity [Amigo]  transferase activity
GO	androgen receptor signaling pathway [Amigo]  androgen receptor signaling pathway
GO	transcription regulator activity [Amigo]  transcription regulator activity
GO	nuclear hormone receptor binding [Amigo]  nuclear hormone receptor binding
GO	positive regulation of transcription, DNA-dependent [Amigo]  positive regulation of transcription, DNA-dependent
GO	protein N-terminus binding [Amigo]  protein N-terminus binding
GO	androgen receptor binding [Amigo]  androgen receptor binding
PubGene	NCOA1
TreeFam	NCOA1
CTD	8648 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NCOA1 Related clones (RZPD - Berlin)
	PubMed
PubMed	113 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:21:40 2008