NKX2-1 (NK2 homeobox 1)

Identity

Other names	BCH
	BHC
	NK-2
	NKX2.1
	NKX2A
	TEBP
	TITF1
	TTF-1
	TTF1
HGNC	NKX2-1
Location	14q13.3
Location_base_pair	Starts at 36055353 and ends at 36059167 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	NKX2-1   11825
Entrez_Gene	NKX2-1  7080  NK2 homeobox 1
	Cards
GeneCards	NKX2-1
Ensembl	NKX2-1 [Search_View]   ENSG00000136352 [Gene_View]
Genatlas	NKX2-1
GeneLynx	NKX2-1
eGenome	NKX2-1
euGene	7080
	Genomic and cartography
GoldenPath	NKX2-1  -  14q13.3   chr14:36055353-36059167 -  14q13.3   [Description]    (hg18-March_2006)
Ensembl	NKX2-1 - 14q13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	NKX2-1
	Gene and transcription
Genbank	BC006221 [ ENTREZ ]
Genbank	BE796718 [ ENTREZ ]
Genbank	BM970838 [ ENTREZ ]
Genbank	BT009773 [ ENTREZ ]
Genbank	CR600885 [ ENTREZ ]
RefSeq	NM_001079668 [ SRS ]    NM_001079668 [ ENTREZ ]
RefSeq	NM_003317 [ SRS ]    NM_003317 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
AceView	NKX2-1 AceView - NCBI
Unigene	Hs.705388 [ SRS ]    Hs.705388 [ NCBI ]     HS705388 [ spliceNest ]
Fast-db	157 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14956 [ SRS]    O14956 [ EXPASY ]     O14956 [ INTERPRO ]     O14956 [ UNIPROT ]
CluSTr	O14956
Blocks	O14956
HPRD	02798
	Protein Interaction databases
DIP	O14956
IntAct	O14956
	Polymorphism : SNP, mutations, diseases
OMIM	118700;600635;610978    [ map ]
GENECLINICS	118700;600635;610978
SNP	NKX2-1 [dbSNP-NCBI]
SNP	NM_001079668 [SNP-NCI]
SNP	NM_003317 [SNP-NCI]
SNP	NKX2-1 [GeneSNPs - Utah]  NKX2-1] [HGBASE - SRS]
HAPMAP	NKX2-1 [HAPMAP]
COSMIC	NKX2-1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	NKX2-1
	General knowledge
Family Browser	NKX2-1 [UCSC Family Browser]
SOURCE	NM_001079668
SOURCE	NM_003317
SMD	Hs.705388
SAGE	Hs.705388
GO	neuron migration [Amigo]  neuron migration
GO	transcription factor activity [Amigo]  transcription factor activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	transcription factor complex [Amigo]  transcription factor complex
GO	pattern specification process [Amigo]  pattern specification process
GO	brain development [Amigo]  brain development
GO	endoderm development [Amigo]  endoderm development
GO	organ morphogenesis [Amigo]  organ morphogenesis
GO	transcription activator activity [Amigo]  transcription activator activity
GO	transcription activator activity [Amigo]  transcription activator activity
GO	forebrain dorsal/ventral pattern formation [Amigo]  forebrain dorsal/ventral pattern formation
GO	lung development [Amigo]  lung development
GO	thyroid gland development [Amigo]  thyroid gland development
GO	sequence-specific DNA binding [Amigo]  sequence-specific DNA binding
GO	positive regulation of transcription from RNA polymerase II promoter [Amigo]  positive regulation of transcription from RNA polymerase II promoter
PubGene	NKX2-1
TreeFam	NKX2-1
CTD	7080 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NKX2-1 Related clones (RZPD - Berlin)
	PubMed
PubMed	69 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:44:50 2008