OGG1 (8-oxoguanine DNA glycosylase)

Identity

Other names	HMMH
	HOGG1
	MUTM
	OGH1
HGNC	OGG1
Location	3p26
Location_base_pair	Starts at 9765705 and ends at 9774087 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	OGG1   8125
Entrez_Gene	OGG1  4968  8-oxoguanine DNA glycosylase
	Cards
GeneCards	OGG1
Ensembl	ENSG00000114026 [Gene_View]  OGG1 [Vega]
Genatlas	OGG1
	Genomic and cartography
GoldenPath	OGG1  -  3p26   chr3:9765705-9774087 +  3p25.3   [Description]    (hg18-March_2006)
Ensembl	OGG1 - 3p25.3 [CytoView]
NCBI	Mapview
OMIM	144700 Disease map [OMIM]
OMIM	601982 Disease map [OMIM]
HomoloGene	OGG1
	Gene and transcription
Genbank	AB000410 [ ENTREZ ]
Genbank	AB019528 [ ENTREZ ]
Genbank	AB019529 [ ENTREZ ]
Genbank	AB019530 [ ENTREZ ]
Genbank	AB019531 [ ENTREZ ]
RefSeq	NM_002542 [ SRS ]    NM_002542 [ ENTREZ ]
RefSeq	NM_016819 [ SRS ]    NM_016819 [ ENTREZ ]
RefSeq	NM_016820 [ SRS ]    NM_016820 [ ENTREZ ]
RefSeq	NM_016821 [ SRS ]    NM_016821 [ ENTREZ ]
RefSeq	NM_016826 [ SRS ]    NM_016826 [ ENTREZ ]
RefSeq	NM_016827 [ SRS ]    NM_016827 [ ENTREZ ]
RefSeq	NM_016828 [ SRS ]    NM_016828 [ ENTREZ ]
RefSeq	NM_016829 [ SRS ]    NM_016829 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838876 [ SRS ]    NW_001838876 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
CCDS	OGG1 CCDS - NCBI
AceView	OGG1 AceView - NCBI
Unigene	Hs.380271 [ SRS ]    Hs.380271 [ NCBI ]
Fast-db	1418 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O15527 [ SRS]    O15527 [ EXPASY ]     O15527 [ INTERPRO ]     O15527 [ UNIPROT ] O15527 [ VarSplice FASTA ]
Interpro	IPR003265 Endo_3c [ SRS ]    IPR003265 Endo_3c [ EBI ]
Interpro	IPR000445 HhH [ SRS ]    IPR000445 HhH [ EBI ]
Interpro	IPR004577 Ogg [ SRS ]    IPR004577 Ogg [ EBI ]
Interpro	IPR012904 OGG_N [ SRS ]    IPR012904 OGG_N [ EBI ]
CluSTr	O15527
Pfam	PF00633 HHH [ SRS ]    PF00633 HHH [ Sanger ]    pfam00633 [ NCBI-CDD ]
Pfam	PF00730 HhH-GPD [ SRS ]    PF00730 HhH-GPD [ Sanger ]    pfam00730 [ NCBI-CDD ]
Pfam	PF07934 OGG_N [ SRS ]    PF07934 OGG_N [ Sanger ]    pfam07934 [ NCBI-CDD ]
Smart	SM00478 ENDO3c [EMBL]
Blocks	O15527
PDB	1EBM [ SRS ]    1EBM [ PdbSum ],   1EBM [ IMB ]   1EBM [ RSDB ]
PDB	1FN7 [ SRS ]    1FN7 [ PdbSum ],   1FN7 [ IMB ]   1FN7 [ RSDB ]
PDB	1HU0 [ SRS ]    1HU0 [ PdbSum ],   1HU0 [ IMB ]   1HU0 [ RSDB ]
PDB	1KO9 [ SRS ]    1KO9 [ PdbSum ],   1KO9 [ IMB ]   1KO9 [ RSDB ]
PDB	1LWV [ SRS ]    1LWV [ PdbSum ],   1LWV [ IMB ]   1LWV [ RSDB ]
PDB	1LWW [ SRS ]    1LWW [ PdbSum ],   1LWW [ IMB ]   1LWW [ RSDB ]
PDB	1LWY [ SRS ]    1LWY [ PdbSum ],   1LWY [ IMB ]   1LWY [ RSDB ]
PDB	1M3H [ SRS ]    1M3H [ PdbSum ],   1M3H [ IMB ]   1M3H [ RSDB ]
PDB	1M3Q [ SRS ]    1M3Q [ PdbSum ],   1M3Q [ IMB ]   1M3Q [ RSDB ]
PDB	1N39 [ SRS ]    1N39 [ PdbSum ],   1N39 [ IMB ]   1N39 [ RSDB ]
PDB	1N3A [ SRS ]    1N3A [ PdbSum ],   1N3A [ IMB ]   1N3A [ RSDB ]
PDB	1N3C [ SRS ]    1N3C [ PdbSum ],   1N3C [ IMB ]   1N3C [ RSDB ]
PDB	1YQK [ SRS ]    1YQK [ PdbSum ],   1YQK [ IMB ]   1YQK [ RSDB ]
PDB	1YQL [ SRS ]    1YQL [ PdbSum ],   1YQL [ IMB ]   1YQL [ RSDB ]
PDB	1YQM [ SRS ]    1YQM [ PdbSum ],   1YQM [ IMB ]   1YQM [ RSDB ]
PDB	1YQR [ SRS ]    1YQR [ PdbSum ],   1YQR [ IMB ]   1YQR [ RSDB ]
PDB	2I5W [ SRS ]    2I5W [ PdbSum ],   2I5W [ IMB ]   2I5W [ RSDB ]
PDB	2NOB [ SRS ]    2NOB [ PdbSum ],   2NOB [ IMB ]   2NOB [ RSDB ]
PDB	2NOE [ SRS ]    2NOE [ PdbSum ],   2NOE [ IMB ]   2NOE [ RSDB ]
PDB	2NOF [ SRS ]    2NOF [ PdbSum ],   2NOF [ IMB ]   2NOF [ RSDB ]
PDB	2NOH [ SRS ]    2NOH [ PdbSum ],   2NOH [ IMB ]   2NOH [ RSDB ]
PDB	2NOI [ SRS ]    2NOI [ PdbSum ],   2NOI [ IMB ]   2NOI [ RSDB ]
PDB	2NOL [ SRS ]    2NOL [ PdbSum ],   2NOL [ IMB ]   2NOL [ RSDB ]
PDB	2NOZ [ SRS ]    2NOZ [ PdbSum ],   2NOZ [ IMB ]   2NOZ [ RSDB ]
HPRD	03582
	Protein Interaction databases
DIP	O15527
IntAct	O15527
	Polymorphism : SNP, mutations, diseases
OMIM	144700    [ map ]
OMIM	601982    [ map ]
GENETests	144700
GENETests	601982
SNP	OGG1 [dbSNP-NCBI]
SNP	NM_002542 [SNP-NCI]
SNP	NM_016819 [SNP-NCI]
SNP	NM_016820 [SNP-NCI]
SNP	NM_016821 [SNP-NCI]
SNP	NM_016826 [SNP-NCI]
SNP	NM_016827 [SNP-NCI]
SNP	NM_016828 [SNP-NCI]
SNP	NM_016829 [SNP-NCI]
SNP	OGG1 [GeneSNPs - Utah]  OGG1] [HGBASE - SRS]
HAPMAP	OGG1 [HAPMAP]
COSMIC	OGG1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	OGG1
Genetic Association	OGG1
CDC HuGE	OGG1
	General knowledge
Family Browser	OGG1 [UCSC Family Browser]
SOURCE	NM_002542
SOURCE	NM_016819
SOURCE	NM_016820
SOURCE	NM_016821
SOURCE	NM_016826
SOURCE	NM_016827
SOURCE	NM_016828
SOURCE	NM_016829
SMD	Hs.380271
SAGE	Hs.380271
Enzyme	3.2.2.- [ Enzyme-Expasy ]   3.2.2.- [ Enzyme-SRS ]   3.2.2.- [ IntEnz-EBI ]   3.2.2.- [ BRENDA ]   3.2.2.- [ KEGG ]
GO	damaged DNA binding [Amigo]  damaged DNA binding
GO	catalytic activity [Amigo]  catalytic activity
GO	endonuclease activity [Amigo]  endonuclease activity
GO	protein binding [Amigo]  protein binding
GO	cellular_component [Amigo]  cellular_component
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	nucleoplasm [Amigo]  nucleoplasm
GO	mitochondrion [Amigo]  mitochondrion
GO	base-excision repair [Amigo]  base-excision repair
GO	base-excision repair [Amigo]  base-excision repair
GO	nucleotide-excision repair [Amigo]  nucleotide-excision repair
GO	metabolic process [Amigo]  metabolic process
GO	oxidized purine base lesion DNA N-glycosylase activity [Amigo]  oxidized purine base lesion DNA N-glycosylase activity
GO	oxidized purine base lesion DNA N-glycosylase activity [Amigo]  oxidized purine base lesion DNA N-glycosylase activity
GO	oxidized purine base lesion DNA N-glycosylase activity [Amigo]  oxidized purine base lesion DNA N-glycosylase activity
GO	hydrolase activity, acting on glycosyl bonds [Amigo]  hydrolase activity, acting on glycosyl bonds
GO	lyase activity [Amigo]  lyase activity
GO	depurination [Amigo]  depurination
PubGene	OGG1
TreeFam	OGG1
CTD	4968 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	OGG1 Related clones (RZPD - Berlin)
	PubMed
PubMed	198 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 16:59:35 2008