OSM (oncostatin M)

Identity

Other names	MGC20461
HGNC	OSM
Location	22q12.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	OSM   8506
Entrez_Gene	OSM  5008  oncostatin M
	Cards
GeneCards	OSM
Ensembl	OSM [Search_View]   ENSG00000099985 [Gene_View]
Genatlas	OSM
GeneLynx	OSM
eGenome	OSM
euGene	5008
	Genomic and cartography
GoldenPath	OSM  -  22q12.2   chr22:28988819-28992840 -  22q12.2   [Description]    (hg18-March_2006)
Ensembl	OSM - 22q12.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	OSM
	Gene and transcription
Genbank	BC011589 [ ENTREZ ]
Genbank	CR456534 [ ENTREZ ]
Genbank	CR541703 [ ENTREZ ]
Genbank	CU013134 [ ENTREZ ]
Genbank	CU013422 [ ENTREZ ]
RefSeq	NM_020530 [ SRS ]    NM_020530 [ ENTREZ ]
RefSeq	AC_000065 [ SRS ]    AC_000065 [ ENTREZ ]
RefSeq	AC_000154 [ SRS ]    AC_000154 [ ENTREZ ]
RefSeq	NC_000022 [ SRS ]    NC_000022 [ ENTREZ ]
RefSeq	NT_011520 [ SRS ]    NT_011520 [ ENTREZ ]
RefSeq	NW_001838745 [ SRS ]    NW_001838745 [ ENTREZ ]
RefSeq	NW_927628 [ SRS ]    NW_927628 [ ENTREZ ]
AceView	OSM AceView - NCBI
Unigene	Hs.248156 [ SRS ]    Hs.248156 [ NCBI ]     HS248156 [ spliceNest ]
Fast-db	4153 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P13725 [ SRS]    P13725 [ EXPASY ]     P13725 [ INTERPRO ]     P13725 [ UNIPROT ]
Prosite	PS00590 LIF_OSM [ SRS ]    PS00590 LIF_OSM [ Expasy ]
Interpro	IPR012351 4_helix_cytokine_core [ SRS ]    IPR012351 4_helix_cytokine_core [ EBI ]
Interpro	IPR001581 LIF_OSM [ SRS ]    IPR001581 LIF_OSM [ EBI ]
CluSTr	P13725
Pfam	PF01291 LIF_OSM [ SRS ]    PF01291 LIF_OSM [ Sanger ]    pfam01291 [ NCBI-CDD ]
Smart	SM00080 LIF_OSM [EMBL]
Prodom	PD023062 Oncostatin[INRA-Toulouse]
Prodom	P13725 ONCM_HUMAN [ Domain structure ]   P13725 ONCM_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P13725
PDB	1EVS [ SRS ]    1EVS [ PdbSum ],   1EVS [ IMB ]   1EVS [ RSDB ]
HPRD	01300
	Protein Interaction databases
DIP	P13725
IntAct	P13725
	Polymorphism : SNP, mutations, diseases
OMIM	165095    [ map ]
GENECLINICS	165095
SNP	OSM [dbSNP-NCBI]
SNP	NM_020530 [SNP-NCI]
SNP	OSM [GeneSNPs - Utah]  OSM] [HGBASE - SRS]
HAPMAP	OSM [HAPMAP]
HGMD	OSM
	General knowledge
Family Browser	OSM [UCSC Family Browser]
SOURCE	NM_020530
SMD	Hs.248156
SAGE	Hs.248156
GO	regulation of cell growth [Amigo]  regulation of cell growth
GO	cytokine activity [Amigo]  cytokine activity
GO	oncostatin-M receptor binding [Amigo]  oncostatin-M receptor binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	apoptosis [Amigo]  apoptosis
GO	immune response [Amigo]  immune response
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	peripheral nervous system development [Amigo]  peripheral nervous system development
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	response to heat [Amigo]  response to heat
GO	positive regulation of peptidyl-serine phosphorylation [Amigo]  positive regulation of peptidyl-serine phosphorylation
GO	tyrosine phosphorylation of Stat3 protein [Amigo]  tyrosine phosphorylation of Stat3 protein
GO	tyrosine phosphorylation of Stat5 protein [Amigo]  tyrosine phosphorylation of Stat5 protein
GO	tyrosine phosphorylation of Stat1 protein [Amigo]  tyrosine phosphorylation of Stat1 protein
GO	positive regulation of MAPKKK cascade [Amigo]  positive regulation of MAPKKK cascade
GO	positive regulation of transcription from RNA polymerase II promoter [Amigo]  positive regulation of transcription from RNA polymerase II promoter
GO	negative regulation of hormone secretion [Amigo]  negative regulation of hormone secretion
GO	behavioral response to pain [Amigo]  behavioral response to pain
GO	positive regulation of peptidyl-tyrosine phosphorylation [Amigo]  positive regulation of peptidyl-tyrosine phosphorylation
KEGG	Cytokine-cytokine receptor interaction
KEGG	Jak-STAT signaling pathway
PubGene	OSM
TreeFam	OSM
CTD	5008 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	OSM Related clones (RZPD - Berlin)
	PubMed
PubMed	61 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:23:19 2008