OTC (ornithine carbamoyltransferase)

Identity

Other names	MGC129967
	MGC129968
	MGC138856
	OCTD
HGNC	OTC
Location	Xp21.1
Location_base_pair	Starts at 38096680 and ends at 38165647 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	OTC   8512
Entrez_Gene	OTC  5009  ornithine carbamoyltransferase
	Cards
GeneCards	OTC
Ensembl	OTC [Search_View]   ENSG00000036473 [Gene_View]
Genatlas	OTC
GeneLynx	OTC
eGenome	OTC
euGene	5009
	Genomic and cartography
GoldenPath	OTC  -  Xp21.1   chrX:38096680-38165647 +  Xp11.4   [Description]    (hg18-March_2006)
Ensembl	OTC - Xp11.4 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	OTC
	Gene and transcription
Genbank	AI247721 [ ENTREZ ]
Genbank	AK292757 [ ENTREZ ]
Genbank	BC074745 [ ENTREZ ]
Genbank	BC107153 [ ENTREZ ]
Genbank	BC107154 [ ENTREZ ]
RefSeq	NM_000531 [ SRS ]    NM_000531 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	AC_000155 [ SRS ]    AC_000155 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_079573 [ SRS ]    NT_079573 [ ENTREZ ]
RefSeq	NW_001842361 [ SRS ]    NW_001842361 [ ENTREZ ]
RefSeq	NW_927701 [ SRS ]    NW_927701 [ ENTREZ ]
AceView	OTC AceView - NCBI
Unigene	Hs.117050 [ SRS ]    Hs.117050 [ NCBI ]     HS117050 [ spliceNest ]
Fast-db	5884 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P00480 [ SRS]    P00480 [ EXPASY ]     P00480 [ INTERPRO ]     P00480 [ UNIPROT ]
Prosite	PS00097 CARBAMOYLTRANSFERASE [ SRS ]    PS00097 CARBAMOYLTRANSFERASE [ Expasy ]
Interpro	IPR006130 Asp/Orn_carbamoyltranf [ SRS ]    IPR006130 Asp/Orn_carbamoyltranf [ EBI ]
Interpro	IPR006132 Asp/Orn_carbamoyltranf_P_bd [ SRS ]    IPR006132 Asp/Orn_carbamoyltranf_P_bd [ EBI ]
Interpro	IPR006131 Asp_carbamoyltransf_Asp/Orn_bd [ SRS ]    IPR006131 Asp_carbamoyltransf_Asp/Orn_bd [ EBI ]
Interpro	IPR002292 Orn_carbamltrans [ SRS ]    IPR002292 Orn_carbamltrans [ EBI ]
CluSTr	P00480
Pfam	PF00185 OTCace [ SRS ]    PF00185 OTCace [ Sanger ]    pfam00185 [ NCBI-CDD ]
Pfam	PF02729 OTCace_N [ SRS ]    PF02729 OTCace_N [ Sanger ]    pfam02729 [ NCBI-CDD ]
Blocks	P00480
PDB	1C9Y [ SRS ]    1C9Y [ PdbSum ],   1C9Y [ IMB ]   1C9Y [ RSDB ]
PDB	1EP9 [ SRS ]    1EP9 [ PdbSum ],   1EP9 [ IMB ]   1EP9 [ RSDB ]
PDB	1FVO [ SRS ]    1FVO [ PdbSum ],   1FVO [ IMB ]   1FVO [ RSDB ]
PDB	1OTH [ SRS ]    1OTH [ PdbSum ],   1OTH [ IMB ]   1OTH [ RSDB ]
HPRD	02408
	Protein Interaction databases
DIP	P00480
IntAct	P00480
	Polymorphism : SNP, mutations, diseases
OMIM	300461;311250    [ map ]
GENECLINICS	300461;311250
SNP	OTC [dbSNP-NCBI]
SNP	NM_000531 [SNP-NCI]
SNP	OTC [GeneSNPs - Utah]  OTC] [HGBASE - SRS]
HAPMAP	OTC [HAPMAP]
COSMIC	OTC [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	OTC
	General knowledge
Family Browser	OTC [UCSC Family Browser]
SOURCE	NM_000531
SMD	Hs.117050
SAGE	Hs.117050
Enzyme	2.1.3.3 [ Enzyme-Expasy ]   2.1.3.3 [ Enzyme-SRS ]   2.1.3.3 [ IntEnz-EBI ]   2.1.3.3 [ BRENDA ]   2.1.3.3 [ KEGG ]   2.1.3.3 [ WIT ]
GO	urea cycle [Amigo]  urea cycle
GO	ornithine carbamoyltransferase activity [Amigo]  ornithine carbamoyltransferase activity
GO	ornithine carbamoyltransferase activity [Amigo]  ornithine carbamoyltransferase activity
GO	phospholipid binding [Amigo]  phospholipid binding
GO	mitochondrion [Amigo]  mitochondrion
GO	mitochondrial inner membrane [Amigo]  mitochondrial inner membrane
GO	mitochondrial matrix [Amigo]  mitochondrial matrix
GO	mitochondrial matrix [Amigo]  mitochondrial matrix
GO	arginine biosynthetic process [Amigo]  arginine biosynthetic process
GO	amino acid biosynthetic process [Amigo]  amino acid biosynthetic process
GO	ornithine carbamoyltransferase complex [Amigo]  ornithine carbamoyltransferase complex
GO	amino acid binding [Amigo]  amino acid binding
GO	transferase activity [Amigo]  transferase activity
GO	phosphate binding [Amigo]  phosphate binding
GO	protein oligomerization [Amigo]  protein oligomerization
KEGG	Urea cycle and metabolism of amino groups
KEGG	Arginine and proline metabolism
PubGene	OTC
TreeFam	OTC
CTD	5009 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	OTC Related clones (RZPD - Berlin)
	PubMed
PubMed	75 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:46:08 2008