PAK6 (p21(CDKN1A)-activated kinase 6)

Identity

Other names	PAK5
Hugo	PAK6
Location	15q14
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	PAK6
GDB	PAK6
Entrez_Gene	PAK6  56924  p21(CDKN1A)-activated kinase 6
	Cards
GeneCards	PAK6
Ensembl	PAK6 [Search_View]   ENSG00000137843 [Gene_View]
Genatlas	PAK6
GeneLynx	PAK6
eGenome	PAK6
euGene	56924
	Genomic and cartography
GoldenPath	PAK6  -  15q14   chr15:38319368-38356979 +  15q15.1   [Description]    (hg18-March_2006)
Ensembl	PAK6 - 15q15.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PAK6
	Gene and transcription
Genbank	AF276893 [ ENTREZ ]
Genbank	AJ236915 [ ENTREZ ]
Genbank	AK131522 [ ENTREZ ]
Genbank	AK290227 [ ENTREZ ]
Genbank	AK315813 [ ENTREZ ]
RefSeq	NM_020168 [ SRS ]    NM_020168 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_925840 [ SRS ]    NW_925840 [ ENTREZ ]
AceView	PAK6 AceView - NCBI
Unigene	Hs.513645 [ SRS ]    Hs.513645 [ NCBI ]     HS513645 [ spliceNest ]
Fast-db	2087 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9NQU5 [ SRS]    Q9NQU5 [ EXPASY ]     Q9NQU5 [ INTERPRO ]
Prosite	PS50108 CRIB [ SRS ]    PS50108 CRIB [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000095 PAK_box_Rho_bd [ SRS ]    IPR000095 PAK_box_Rho_bd [ EBI ]
Interpro	IPR015750 Pak_like [ SRS ]    IPR015750 Pak_like [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q9NQU5
Pfam	PF00786 PBD [ SRS ]    PF00786 PBD [ Sanger ]    pfam00786 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00285 PBD [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q9NQU5 PAK6_HUMAN [ Domain structure ]   Q9NQU5 PAK6_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q9NQU5
PDB	2C30 [ SRS ]    2C30 [ PdbSum ],   2C30 [ IMB ]   2C30 [ RSDB ]
PDB	2ODB [ SRS ]    2ODB [ PdbSum ],   2ODB [ IMB ]   2ODB [ RSDB ]
HPRD	06426
	Protein Interaction databases
DIP	Q9NQU5
IntAct	Q9NQU5
	Polymorphism : SNP, mutations, diseases
OMIM	608110    [ map ]
GENECLINICS	608110
SNP	PAK6 [dbSNP-NCBI]
SNP	NM_020168 [SNP-NCI]
SNP	PAK6 [GeneSNPs - Utah]  PAK6] [HGBASE - SRS]
HAPMAP	PAK6 [HAPMAP]
COSMIC	PAK6 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PAK6
	General knowledge
Family Browser	PAK6 [UCSC Family Browser]
SOURCE	NM_020168
SMD	Hs.513645
SAGE	Hs.513645
Enzyme	2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ Brenda-SRS ]   2.7.11.1 [ KEGG ]   2.7.11.1 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	transferase activity [Amigo]  transferase activity
KEGG	Axon guidance
KEGG	Focal adhesion
KEGG	T cell receptor signaling pathway
KEGG	Regulation of actin cytoskeleton
PubGene	PAK6
TreeFam	PAK6
CTD	56924 [Comparative Genomics Database]
	Other databases
	Probes
Probe	PAK6 Related clones (RZPD - Berlin)
	PubMed
PubMed	10 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:20:14 2008