PAK7 (p21 protein (Cdc42/Rac)-activated kinase 7)

Identity

Other names	KIAA1264
	MGC26232
	PAK5
HGNC	PAK7
Location	20p12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PAK7   15916
Entrez_Gene	PAK7  57144  p21 protein (Cdc42/Rac)-activated kinase 7
	Cards
GeneCards	PAK7
Ensembl	PAK7 [Search_View]   ENSG00000101349 [Gene_View]
Genatlas	PAK7
GeneLynx	PAK7
eGenome	PAK7
euGene	57144
	Genomic and cartography
GoldenPath	PAK7  -  20p12   chr20:9466037-9767687 -  20p12.2   [Description]    (hg18-March_2006)
Ensembl	PAK7 - 20p12.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PAK7
	Gene and transcription
Genbank	AB033090 [ ENTREZ ]
Genbank	AB040812 [ ENTREZ ]
Genbank	AK095674 [ ENTREZ ]
Genbank	AK291401 [ ENTREZ ]
Genbank	AK307926 [ ENTREZ ]
RefSeq	NM_020341 [ SRS ]    NM_020341 [ ENTREZ ]
RefSeq	NM_177990 [ SRS ]    NM_177990 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	PAK7 AceView - NCBI
Unigene	Hs.32539 [ SRS ]    Hs.32539 [ NCBI ]     HS32539 [ spliceNest ]
Fast-db	5513 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q8TB93 [ SRS]    Q8TB93 [ EXPASY ]     Q8TB93 [ INTERPRO ]     Q8TB93 [ UNIPROT ]
Prosite	PS50108 CRIB [ SRS ]    PS50108 CRIB [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Interpro	IPR000095 PAK_box_Rho_bd [ SRS ]    IPR000095 PAK_box_Rho_bd [ EBI ]
Interpro	IPR015750 Pak_like [ SRS ]    IPR015750 Pak_like [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q8TB93
Pfam	PF00786 PBD [ SRS ]    PF00786 PBD [ Sanger ]    pfam00786 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00285 PBD [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q8TB93 Q8TB93_HUMAN [ Domain structure ]   Q8TB93 Q8TB93_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q8TB93
HPRD	06423
	Protein Interaction databases
DIP	Q8TB93
IntAct	Q8TB93
	Polymorphism : SNP, mutations, diseases
OMIM	608038    [ map ]
GENECLINICS	608038
SNP	PAK7 [dbSNP-NCBI]
SNP	NM_020341 [SNP-NCI]
SNP	NM_177990 [SNP-NCI]
SNP	PAK7 [GeneSNPs - Utah]  PAK7] [HGBASE - SRS]
HAPMAP	PAK7 [HAPMAP]
COSMIC	PAK7 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PAK7
	General knowledge
Family Browser	PAK7 [UCSC Family Browser]
SOURCE	NM_020341
SOURCE	NM_177990
SMD	Hs.32539
SAGE	Hs.32539
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	mitochondrion [Amigo]  mitochondrion
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	anti-apoptosis [Amigo]  anti-apoptosis
GO	transferase activity [Amigo]  transferase activity
KEGG	Axon guidance
KEGG	Focal adhesion
KEGG	T cell receptor signaling pathway
KEGG	Regulation of actin cytoskeleton
PubGene	PAK7
TreeFam	PAK7
CTD	57144 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PAK7 Related clones (RZPD - Berlin)
	PubMed
PubMed	17 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:23:37 2008