PCNA (proliferating cell nuclear antigen)

Identity

Other names	MGC8367
HGNC	PCNA
Location	20pter-p12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PCNA   8729
Entrez_Gene	PCNA  5111  proliferating cell nuclear antigen
	Cards
GeneCards	PCNA
Ensembl	PCNA [Search_View]   ENSG00000132646 [Gene_View]
Genatlas	PCNA
GeneLynx	PCNA
eGenome	PCNA
euGene	5111
	Genomic and cartography
GoldenPath	PCNA  -     chr20:5043599-5055268 -  20p12.3   [Description]    (hg18-March_2006)
Ensembl	PCNA - 20p12.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PCNA
	Gene and transcription
Genbank	AK313286 [ ENTREZ ]
Genbank	BC000491 [ ENTREZ ]
Genbank	BC062439 [ ENTREZ ]
Genbank	BG612192 [ ENTREZ ]
Genbank	BU626265 [ ENTREZ ]
RefSeq	NM_002592 [ SRS ]    NM_002592 [ ENTREZ ]
RefSeq	NM_182649 [ SRS ]    NM_182649 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	PCNA AceView - NCBI
Unigene	Hs.147433 [ SRS ]    Hs.147433 [ NCBI ]     HS147433 [ spliceNest ]
Fast-db	4576 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P12004 [ SRS]    P12004 [ EXPASY ]     P12004 [ INTERPRO ]     P12004 [ UNIPROT ]
Prosite	PS01251 PCNA_1 [ SRS ]    PS01251 PCNA_1 [ Expasy ]
Prosite	PS00293 PCNA_2 [ SRS ]    PS00293 PCNA_2 [ Expasy ]
Interpro	IPR000730 Pr_cel_nuc_antig [ SRS ]    IPR000730 Pr_cel_nuc_antig [ EBI ]
CluSTr	P12004
Pfam	PF02747 PCNA_C [ SRS ]    PF02747 PCNA_C [ Sanger ]    pfam02747 [ NCBI-CDD ]
Pfam	PF00705 PCNA_N [ SRS ]    PF00705 PCNA_N [ Sanger ]    pfam00705 [ NCBI-CDD ]
Prodom	PD002673 Pr_cel_nuc_antig[INRA-Toulouse]
Prodom	P12004 PCNA_HUMAN [ Domain structure ]   P12004 PCNA_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P12004
PDB	1AXC [ SRS ]    1AXC [ PdbSum ],   1AXC [ IMB ]   1AXC [ RSDB ]
PDB	1U76 [ SRS ]    1U76 [ PdbSum ],   1U76 [ IMB ]   1U76 [ RSDB ]
PDB	1U7B [ SRS ]    1U7B [ PdbSum ],   1U7B [ IMB ]   1U7B [ RSDB ]
PDB	1UL1 [ SRS ]    1UL1 [ PdbSum ],   1UL1 [ IMB ]   1UL1 [ RSDB ]
PDB	1VYJ [ SRS ]    1VYJ [ PdbSum ],   1VYJ [ IMB ]   1VYJ [ RSDB ]
PDB	1VYM [ SRS ]    1VYM [ PdbSum ],   1VYM [ IMB ]   1VYM [ RSDB ]
PDB	1W60 [ SRS ]    1W60 [ PdbSum ],   1W60 [ IMB ]   1W60 [ RSDB ]
HPRD	01456
	Protein Interaction databases
DIP	P12004
IntAct	P12004
	Polymorphism : SNP, mutations, diseases
OMIM	176740    [ map ]
GENECLINICS	176740
SNP	PCNA [dbSNP-NCBI]
SNP	NM_002592 [SNP-NCI]
SNP	NM_182649 [SNP-NCI]
SNP	PCNA [GeneSNPs - Utah]  PCNA] [HGBASE - SRS]
HAPMAP	PCNA [HAPMAP]
COSMIC	PCNA [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PCNA
	General knowledge
Family Browser	PCNA [UCSC Family Browser]
SOURCE	NM_002592
SOURCE	NM_182649
SMD	Hs.147433
SAGE	Hs.147433
GO	cyclin-dependent protein kinase holoenzyme complex [Amigo]  cyclin-dependent protein kinase holoenzyme complex
GO	DNA binding [Amigo]  DNA binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nuclear lamina [Amigo]  nuclear lamina
GO	nucleoplasm [Amigo]  nucleoplasm
GO	DNA replication factor C complex [Amigo]  DNA replication factor C complex
GO	regulation of DNA replication [Amigo]  regulation of DNA replication
GO	DNA repair [Amigo]  DNA repair
GO	base-excision repair, gap-filling [Amigo]  base-excision repair, gap-filling
GO	nucleotide-excision repair, DNA gap filling [Amigo]  nucleotide-excision repair, DNA gap filling
GO	intracellular protein transport [Amigo]  intracellular protein transport
GO	cell proliferation [Amigo]  cell proliferation
GO	DNA polymerase processivity factor activity [Amigo]  DNA polymerase processivity factor activity
GO	MutLalpha complex binding [Amigo]  MutLalpha complex binding
GO	PCNA complex [Amigo]  PCNA complex
GO	phosphoinositide-mediated signaling [Amigo]  phosphoinositide-mediated signaling
BIOCARTA	p53 Signaling Pathway    [Genes]
KEGG	Cell cycle
PubGene	PCNA
TreeFam	PCNA
CTD	5111 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PCNA Related clones (RZPD - Berlin)
	PubMed
PubMed	228 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:23:57 2008