| Nomenclature | | Hugo | PDHA1 |
| GDB | PDHA1 |
| Entrez_Gene | PDHA1 5160 pyruvate dehydrogenase (lipoamide) alpha 1 |
| Cards |
|---|
| GeneCards | PDHA1 |
| Ensembl | PDHA1 [Search_View] ENSG00000131828 [Gene_View] |
| Genatlas | PDHA1 |
| GeneLynx | PDHA1 |
| eGenome | PDHA1 |
| euGene | 5160 |
| Genomic and cartography |
|---|
| GoldenPath | PDHA1 - chrX:19271972-19287886 + Xp22.12 [Description] (hg18-March_2006) |
| Ensembl | PDHA1 - Xp22.12 [CytoView] |
| NCBI | Mapview |
| OMIM | Disease map [OMIM] |
| HomoloGene | PDHA1 |
| Gene and transcription | | Genbank | AK129887 [ ENTREZ ] |
| Genbank | AK222740 [ ENTREZ ] |
| Genbank | AK222988 [ ENTREZ ] |
| Genbank | AW204705 [ ENTREZ ] |
| Genbank | BC002406 [ ENTREZ ] |
| RefSeq | NM_000284 [ SRS ] NM_000284 [ ENTREZ ] |
| RefSeq | AC_000066 [ SRS ] AC_000066 [ ENTREZ ] |
| RefSeq | NC_000023 [ SRS ] NC_000023 [ ENTREZ ] |
| RefSeq | NT_011757 [ SRS ] NT_011757 [ ENTREZ ] |
| RefSeq | NW_927700 [ SRS ] NW_927700 [ ENTREZ ] |
| AceView | PDHA1 AceView - NCBI |
| Unigene | Hs.530331 [ SRS ] Hs.530331 [ NCBI ]
HS530331 [ spliceNest ] |
| Fast-db | 3450 (alternative variants) |
| Protein : pattern, domain, 3D structure |
|---|
| SwissProt | P08559 [ SRS] P08559 [ EXPASY ] P08559 [ INTERPRO ] |
| Interpro | IPR001017 DHase_E1 [ SRS ] IPR001017 DHase_E1 [ EBI ] |
| CluSTr | P08559 |
| Pfam | PF00676 E1_dh [ SRS ] PF00676 E1_dh [ Sanger ] pfam00676 [ NCBI-CDD ] |
| Blocks | P08559 |
| PDB | 1NI4 [ SRS ] 1NI4 [ PdbSum ], 1NI4 [ IMB ] 1NI4 [ RSDB ] |
| PDB | 2OZL [ SRS ] 2OZL [ PdbSum ], 2OZL [ IMB ] 2OZL [ RSDB ] |
| HPRD | 02420 |
| Protein Interaction databases |
|---|
| DIP | P08559 |
| IntAct | P08559 |
| Polymorphism : SNP, mutations, diseases |
|---|
| OMIM | 300502;308930;312170 [ map ] |
| GENECLINICS | 300502;308930;312170 |
| SNP | PDHA1 [dbSNP-NCBI] |
| SNP | NM_000284 [SNP-NCI] |
| SNP | PDHA1 [GeneSNPs - Utah] PDHA1] [HGBASE - SRS] |
| HAPMAP | PDHA1 [HAPMAP] |
| COSMIC | PDHA1 [Somatic mutation (COSMIC-CGP-Sanger)] |
| HGMD | PDHA1 |
| General knowledge |
|---|
| Family Browser | PDHA1 [UCSC Family Browser] |
| SOURCE | NM_000284 |
| SMD | Hs.530331 |
| SAGE | Hs.530331 |
| Enzyme | 1.2.4.1
[ Enzyme-SRS ] 1.2.4.1
[ Brenda-SRS ] 1.2.4.1
[ KEGG ] 1.2.4.1
[ WIT ] |
| GO | pyruvate dehydrogenase (acetyl-transferring) activity [Amigo] pyruvate dehydrogenase (acetyl-transferring) activity |
| GO | protein binding [Amigo] protein binding |
| GO | mitochondrion [Amigo] mitochondrion |
| GO | mitochondrial matrix [Amigo] mitochondrial matrix |
| GO | acetyl-CoA metabolic process [Amigo] acetyl-CoA metabolic process |
| GO | glycolysis [Amigo] glycolysis |
| GO | metabolic process [Amigo] metabolic process |
| GO | oxidoreductase activity [Amigo] oxidoreductase activity |
| GO | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Amigo] oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| BIOCARTA | Shuttle for transfer of acetyl groups from mitochondria to the cytosol [Genes] |
| KEGG | Glycolysis / Gluconeogenesis |
| KEGG | Alanine and aspartate metabolism |
| KEGG | Valine, leucine and isoleucine biosynthesis |
| KEGG | Pyruvate metabolism |
| KEGG | Butanoate metabolism |
| PubGene | PDHA1 |
| TreeFam | PDHA1 |
| CTD | 5160 [Comparative Genomics Database] |
| Other databases |
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| Probes |
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| Probe | PDHA1 Related clones (RZPD - Berlin) |
| PubMed |
|---|
| PubMed | 50 Pubmed reference(s) in LocusLink |
