PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3)

Identity

Other names	IPFK2
	PFK2
HGNC	PFKFB3
Location	10p15.1
Location_base_pair	Starts at 6284901 and ends at 6317501 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PFKFB3   8874
Entrez_Gene	PFKFB3  5209  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
	Cards
GeneCards	PFKFB3
Ensembl	ENSG00000170525 [Gene_View]  PFKFB3 [Vega]
Genatlas	PFKFB3
	Genomic and cartography
GoldenPath	PFKFB3  -  10p15.1   chr10:6284901-6317501 +  10p15.1   [Description]    (hg18-March_2006)
Ensembl	PFKFB3 - 10p15.1 [CytoView]
NCBI	Mapview
OMIM	605319 Disease map [OMIM]
HomoloGene	PFKFB3
	Gene and transcription
Genbank	AF056320 [ ENTREZ ]
Genbank	AF109735 [ ENTREZ ]
Genbank	AJ272438 [ ENTREZ ]
Genbank	AJ272439 [ ENTREZ ]
Genbank	AJ295747 [ ENTREZ ]
RefSeq	NM_004566 [ SRS ]    NM_004566 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_077569 [ SRS ]    NT_077569 [ ENTREZ ]
RefSeq	NW_001837931 [ SRS ]    NW_001837931 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
CCDS	PFKFB3 CCDS - NCBI
AceView	PFKFB3 AceView - NCBI
Unigene	Hs.714299 [ SRS ]    Hs.714299 [ NCBI ]
Fast-db	18015 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O60352 [ SRS]    O60352 [ EXPASY ]     O60352 [ INTERPRO ]     O60352 [ UNIPROT ] O60352 [ VarSplice FASTA ]
Interpro	IPR003094 6Pfruct_kin [ SRS ]    IPR003094 6Pfruct_kin [ EBI ]
Interpro	IPR013079 6Phosfructo_kin [ SRS ]    IPR013079 6Phosfructo_kin [ EBI ]
CluSTr	O60352
Pfam	PF01591 6PF2K [ SRS ]    PF01591 6PF2K [ Sanger ]    pfam01591 [ NCBI-CDD ]
Blocks	O60352
HPRD	05612
	Protein Interaction databases
DIP	O60352
IntAct	O60352
	Polymorphism : SNP, mutations, diseases
OMIM	605319    [ map ]
GENETests	605319
SNP	PFKFB3 [dbSNP-NCBI]
SNP	NM_004566 [SNP-NCI]
SNP	PFKFB3 [GeneSNPs - Utah]  PFKFB3] [HGBASE - SRS]
HAPMAP	PFKFB3 [HAPMAP]
HGMD	PFKFB3
Genetic Association	PFKFB3
CDC HuGE	PFKFB3
	General knowledge
Family Browser	PFKFB3 [UCSC Family Browser]
SOURCE	NM_004566
SMD	Hs.714299
SAGE	Hs.714299
GO	nucleotide binding [Amigo]  nucleotide binding
GO	catalytic activity [Amigo]  catalytic activity
GO	6-phosphofructo-2-kinase activity [Amigo]  6-phosphofructo-2-kinase activity
GO	6-phosphofructo-2-kinase activity [Amigo]  6-phosphofructo-2-kinase activity
GO	6-phosphofructo-2-kinase activity [Amigo]  6-phosphofructo-2-kinase activity
GO	fructose-2,6-bisphosphate 2-phosphatase activity [Amigo]  fructose-2,6-bisphosphate 2-phosphatase activity
GO	fructose-2,6-bisphosphate 2-phosphatase activity [Amigo]  fructose-2,6-bisphosphate 2-phosphatase activity
GO	ATP binding [Amigo]  ATP binding
GO	cellular_component [Amigo]  cellular_component
GO	cytosol [Amigo]  cytosol
GO	fructose 2,6-bisphosphate metabolic process [Amigo]  fructose 2,6-bisphosphate metabolic process
GO	fructose 2,6-bisphosphate metabolic process [Amigo]  fructose 2,6-bisphosphate metabolic process
GO	metabolic process [Amigo]  metabolic process
GO	kinase activity [Amigo]  kinase activity
GO	transferase activity [Amigo]  transferase activity
GO	hydrolase activity [Amigo]  hydrolase activity
GO	identical protein binding [Amigo]  identical protein binding
KEGG	Fructose and mannose metabolism
PubGene	PFKFB3
TreeFam	PFKFB3
CTD	5209 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PFKFB3 Related clones (RZPD - Berlin)
	PubMed
PubMed	26 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:00:52 2008