PFKL (phosphofructokinase, liver)

Identity

Other names	DKFZp686G1648
	DKFZp686L2097
	FLJ30173
	FLJ40909
	PFK-B
HGNC	PFKL
Location	21q22.3
Location_base_pair	Starts at 44544358 and ends at 44571684 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PFKL   8876
Entrez_Gene	PFKL  5211  phosphofructokinase, liver
	Cards
GeneCards	PFKL
Ensembl	PFKL [Search_View]   ENSG00000141959 [Gene_View]
Genatlas	PFKL
GeneLynx	PFKL
eGenome	PFKL
euGene	5211
	Genomic and cartography
GoldenPath	PFKL  -  21q22.3   chr21:44544358-44571684 +  21q22.3   [Description]    (hg18-March_2006)
Ensembl	PFKL - 21q22.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PFKL
	Gene and transcription
Genbank	AB209127 [ ENTREZ ]
Genbank	AK054735 [ ENTREZ ]
Genbank	AK091488 [ ENTREZ ]
Genbank	AK098228 [ ENTREZ ]
Genbank	AK308437 [ ENTREZ ]
RefSeq	NM_001002021 [ SRS ]    NM_001002021 [ ENTREZ ]
RefSeq	NM_002626 [ SRS ]    NM_002626 [ ENTREZ ]
RefSeq	AC_000064 [ SRS ]    AC_000064 [ ENTREZ ]
RefSeq	AC_000153 [ SRS ]    AC_000153 [ ENTREZ ]
RefSeq	NC_000021 [ SRS ]    NC_000021 [ ENTREZ ]
RefSeq	NT_011515 [ SRS ]    NT_011515 [ ENTREZ ]
RefSeq	NW_001838716 [ SRS ]    NW_001838716 [ ENTREZ ]
RefSeq	NW_927384 [ SRS ]    NW_927384 [ ENTREZ ]
AceView	PFKL AceView - NCBI
Unigene	Hs.255093 [ SRS ]    Hs.255093 [ NCBI ]     HS255093 [ spliceNest ]
Fast-db	3978 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P17858 [ SRS]    P17858 [ EXPASY ]     P17858 [ INTERPRO ]     P17858 [ UNIPROT ]
Prosite	PS00433 PHOSPHOFRUCTOKINASE [ SRS ]    PS00433 PHOSPHOFRUCTOKINASE [ Expasy ]
Interpro	IPR009161 6-phosphofructokinase_euk [ SRS ]    IPR009161 6-phosphofructokinase_euk [ EBI ]
Interpro	IPR015912 Phosphofructokinase_CS [ SRS ]    IPR015912 Phosphofructokinase_CS [ EBI ]
Interpro	IPR000023 Ppfruckinase [ SRS ]    IPR000023 Ppfruckinase [ EBI ]
CluSTr	P17858
Pfam	PF00365 PFK [ SRS ]    PF00365 PFK [ Sanger ]    pfam00365 [ NCBI-CDD ]
Prodom	PD000707 Ppfruckinase[INRA-Toulouse]
Prodom	P17858 K6PL_HUMAN [ Domain structure ]   P17858 K6PL_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P17858
HPRD	01385
	Protein Interaction databases
DIP	P17858
IntAct	P17858
	Polymorphism : SNP, mutations, diseases
OMIM	171860    [ map ]
GENECLINICS	171860
SNP	PFKL [dbSNP-NCBI]
SNP	NM_001002021 [SNP-NCI]
SNP	NM_002626 [SNP-NCI]
SNP	PFKL [GeneSNPs - Utah]  PFKL] [HGBASE - SRS]
HAPMAP	PFKL [HAPMAP]
COSMIC	PFKL [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PFKL
	General knowledge
Family Browser	PFKL [UCSC Family Browser]
SOURCE	NM_001002021
SOURCE	NM_002626
SMD	Hs.255093
SAGE	Hs.255093
Enzyme	2.7.1.11 [ Enzyme-Expasy ]   2.7.1.11 [ Enzyme-SRS ]   2.7.1.11 [ IntEnz-EBI ]   2.7.1.11 [ BRENDA ]   2.7.1.11 [ KEGG ]   2.7.1.11 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	6-phosphofructokinase activity [Amigo]  6-phosphofructokinase activity
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	6-phosphofructokinase complex [Amigo]  6-phosphofructokinase complex
GO	fructose 6-phosphate metabolic process [Amigo]  fructose 6-phosphate metabolic process
GO	regulation of glycolysis [Amigo]  regulation of glycolysis
GO	kinase activity [Amigo]  kinase activity
GO	transferase activity [Amigo]  transferase activity
BIOCARTA	Glycolysis Pathway    [Genes]
KEGG	Glycolysis / Gluconeogenesis
KEGG	Pentose phosphate pathway
KEGG	Fructose and mannose metabolism
KEGG	Galactose metabolism
KEGG	Insulin signaling pathway
PubGene	PFKL
TreeFam	PFKL
CTD	5211 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PFKL Related clones (RZPD - Berlin)
	PubMed
PubMed	25 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:54:42 2008