PHOX2B (paired-like homeobox 2b)

Identity

Other names	NBPhox
	PMX2B
HGNC	PHOX2B
Location	4p13
Location_base_pair	Starts at 41440856 and ends at 41445744 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PHOX2B   9143
Entrez_Gene	PHOX2B  8929  paired-like homeobox 2b
	Cards
GeneCards	PHOX2B
Ensembl	ENSG00000109132 [Gene_View]  PHOX2B [Vega]
Genatlas	PHOX2B
	Genomic and cartography
GoldenPath	PHOX2B  -  4p13   chr4:41440856-41445744 -  4p13   [Description]    (hg18-March_2006)
Ensembl	PHOX2B - 4p13 [CytoView]
NCBI	Mapview
OMIM	142623 Disease map [OMIM]
OMIM	209880 Disease map [OMIM]
OMIM	256700 Disease map [OMIM]
OMIM	603851 Disease map [OMIM]
HomoloGene	PHOX2B
	Gene and transcription
Genbank	AI266171 [ ENTREZ ]
Genbank	BC017199 [ ENTREZ ]
Genbank	CR592141 [ ENTREZ ]
Genbank	CR603200 [ ENTREZ ]
Genbank	CR615256 [ ENTREZ ]
RefSeq	NM_003924 [ SRS ]    NM_003924 [ ENTREZ ]
RefSeq	AC_000047 [ SRS ]    AC_000047 [ ENTREZ ]
RefSeq	AC_000136 [ SRS ]    AC_000136 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NG_008243 [ SRS ]    NG_008243 [ ENTREZ ]
RefSeq	NT_006238 [ SRS ]    NT_006238 [ ENTREZ ]
RefSeq	NW_001838903 [ SRS ]    NW_001838903 [ ENTREZ ]
RefSeq	NW_922073 [ SRS ]    NW_922073 [ ENTREZ ]
CCDS	PHOX2B CCDS - NCBI
AceView	PHOX2B AceView - NCBI
Unigene	Hs.87202 [ SRS ]    Hs.87202 [ NCBI ]
Fast-db	3852 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q99453 [ SRS]    Q99453 [ EXPASY ]     Q99453 [ INTERPRO ]     Q99453 [ UNIPROT ] Q99453 [ VarSplice FASTA ]
Prosite	PS00027 HOMEOBOX_1 [ SRS ]    PS00027 HOMEOBOX_1 [ Expasy ]
Prosite	PS50071 HOMEOBOX_2 [ SRS ]    PS50071 HOMEOBOX_2 [ Expasy ]
Interpro	IPR001356 Homeobox [ SRS ]    IPR001356 Homeobox [ EBI ]
Interpro	IPR012287 Homeodomain-rel [ SRS ]    IPR012287 Homeodomain-rel [ EBI ]
CluSTr	Q99453
Pfam	PF00046 Homeobox [ SRS ]    PF00046 Homeobox [ Sanger ]    pfam00046 [ NCBI-CDD ]
Smart	SM00389 HOX [EMBL]
Prodom	PD000010 Homeobox[INRA-Toulouse]
Prodom	Q99453 PHX2B_HUMAN [ Domain structure ]   Q99453 PHX2B_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q99453
HPRD	09157
	Protein Interaction databases
DIP	Q99453
IntAct	Q99453
	Polymorphism : SNP, mutations, diseases
OMIM	142623    [ map ]
OMIM	209880    [ map ]
OMIM	256700    [ map ]
OMIM	603851    [ map ]
GENETests	142623
GENETests	209880
GENETests	256700
GENETests	603851
SNP	PHOX2B [dbSNP-NCBI]
SNP	NM_003924 [SNP-NCI]
SNP	PHOX2B [GeneSNPs - Utah]  PHOX2B] [HGBASE - SRS]
HAPMAP	PHOX2B [HAPMAP]
COSMIC	PHOX2B [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PHOX2B
Genetic Association	PHOX2B
CDC HuGE	PHOX2B
	General knowledge
Family Browser	PHOX2B [UCSC Family Browser]
SOURCE	NM_003924
SMD	Hs.87202
SAGE	Hs.87202
GO	transcription factor activity [Amigo]  transcription factor activity
GO	transcription cofactor activity [Amigo]  transcription cofactor activity
GO	nucleus [Amigo]  nucleus
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	nervous system development [Amigo]  nervous system development
GO	sequence-specific DNA binding [Amigo]  sequence-specific DNA binding
GO	cell development [Amigo]  cell development
PubGene	PHOX2B
TreeFam	PHOX2B
CTD	8929 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PHOX2B Related clones (RZPD - Berlin)
	PubMed
PubMed	48 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:01:07 2008