PMS2 (PMS2 postmeiotic segregation increased 2 (S. cerevisiae))

Identity

Other names	HNPCC4
	PMS2CL
	PMSL2
HGNC	PMS2
Location	7p22.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PMS2   9122
Entrez_Gene	PMS2  5395  PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
	Cards
GeneCards	PMS2
Ensembl	PMS2 [Search_View]   ENSG00000122512 [Gene_View]
Genatlas	PMS2
GeneLynx	PMS2
eGenome	PMS2
euGene	5395
	Genomic and cartography
GoldenPath	PMS2  -  7p22.1   chr7:5979396-6015263 -  7p22.1   [Description]    (hg18-March_2006)
Ensembl	PMS2 - 7p22.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PMS2
	Gene and transcription
Genbank	AB103082 [ ENTREZ ]
Genbank	AB103083 [ ENTREZ ]
Genbank	AB103085 [ ENTREZ ]
Genbank	AB103086 [ ENTREZ ]
Genbank	AI433648 [ ENTREZ ]
RefSeq	NM_000535 [ SRS ]    NM_000535 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001839002 [ SRS ]    NW_001839002 [ ENTREZ ]
RefSeq	NW_923217 [ SRS ]    NW_923217 [ ENTREZ ]
AceView	PMS2 AceView - NCBI
Unigene	Hs.632637 [ SRS ]    Hs.632637 [ NCBI ]     HS632637 [ spliceNest ]
Fast-db	1623 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P54278 [ SRS]    P54278 [ EXPASY ]     P54278 [ INTERPRO ]     P54278 [ UNIPROT ]
Prosite	PS00058 DNA_MISMATCH_REPAIR_1 [ SRS ]    PS00058 DNA_MISMATCH_REPAIR_1 [ Expasy ]
Interpro	IPR003594 ATP_bd_ATPase [ SRS ]    IPR003594 ATP_bd_ATPase [ EBI ]
Interpro	IPR002099 DNA_mismatch_repair [ SRS ]    IPR002099 DNA_mismatch_repair [ EBI ]
Interpro	IPR013507 DNA_mismatch_repair_C [ SRS ]    IPR013507 DNA_mismatch_repair_C [ EBI ]
Interpro	IPR014762 DNA_mismatch_repair_CS [ SRS ]    IPR014762 DNA_mismatch_repair_CS [ EBI ]
Interpro	IPR014763 DNA_mismatch_repair_N [ SRS ]    IPR014763 DNA_mismatch_repair_N [ EBI ]
Interpro	IPR014790 MutL_C [ SRS ]    IPR014790 MutL_C [ EBI ]
Interpro	IPR015434 PMS2 [ SRS ]    IPR015434 PMS2 [ EBI ]
Interpro	IPR014721 Ribosomal_S5_D2-type_fold [ SRS ]    IPR014721 Ribosomal_S5_D2-type_fold [ EBI ]
CluSTr	P54278
Pfam	PF01119 DNA_mis_repair [ SRS ]    PF01119 DNA_mis_repair [ Sanger ]    pfam01119 [ NCBI-CDD ]
Pfam	PF02518 HATPase_c [ SRS ]    PF02518 HATPase_c [ Sanger ]    pfam02518 [ NCBI-CDD ]
Pfam	PF08676 MutL_C [ SRS ]    PF08676 MutL_C [ Sanger ]    pfam08676 [ NCBI-CDD ]
Smart	SM00387 HATPase_c [EMBL]
Blocks	P54278
PDB	1EA6 [ SRS ]    1EA6 [ PdbSum ],   1EA6 [ IMB ]   1EA6 [ RSDB ]
PDB	1H7S [ SRS ]    1H7S [ PdbSum ],   1H7S [ IMB ]   1H7S [ RSDB ]
PDB	1H7U [ SRS ]    1H7U [ PdbSum ],   1H7U [ IMB ]   1H7U [ RSDB ]
HPRD	02598
	Protein Interaction databases
DIP	P54278
IntAct	P54278
	Polymorphism : SNP, mutations, diseases
OMIM	276300;600259;608623    [ map ]
GENECLINICS	276300;600259;608623
SNP	PMS2 [dbSNP-NCBI]
SNP	NM_000535 [SNP-NCI]
SNP	PMS2 [GeneSNPs - Utah]  PMS2] [HGBASE - SRS]
HAPMAP	PMS2 [HAPMAP]
COSMIC	PMS2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PMS2
	General knowledge
Family Browser	PMS2 [UCSC Family Browser]
SOURCE	NM_000535
SMD	Hs.632637
SAGE	Hs.632637
Enzyme	3.1.-.- [ Enzyme-Expasy ]   3.1.-.- [ Enzyme-SRS ]   3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   3.1.-.- [ WIT ]
GO	DNA binding [Amigo]  DNA binding
GO	single-stranded DNA binding [Amigo]  single-stranded DNA binding
GO	endonuclease activity [Amigo]  endonuclease activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	mismatch repair [Amigo]  mismatch repair
GO	mismatch repair [Amigo]  mismatch repair
GO	hydrolase activity [Amigo]  hydrolase activity
GO	mismatched DNA binding [Amigo]  mismatched DNA binding
GO	single base insertion or deletion binding [Amigo]  single base insertion or deletion binding
GO	MutSalpha complex binding [Amigo]  MutSalpha complex binding
GO	negative regulation of cell cycle [Amigo]  negative regulation of cell cycle
PubGene	PMS2
TreeFam	PMS2
CTD	5395 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PMS2 Related clones (RZPD - Berlin)
	PubMed
PubMed	65 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:25:28 2008