Identity
HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
CALNA3,CNA3,PP2Bgamma
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5533
MIM: 114107
HGNC: 9316
Ensembl: ENSG00000120910
Variants:
dbSNP: 5533
ClinVar: 5533
TCGA: ENSG00000120910
COSMIC: PPP3CC
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA248 | NFKB1 | Gene | Pathway | associated | 23922006 | ||
| PA296 | RELA | Gene | Pathway | associated | 23922006 | ||
| PA31582 | NFATC1 | Gene | Pathway | associated | 23922006 | ||
| PA31583 | NFATC2 | Gene | Pathway | associated | 23922006 | ||
| PA31584 | NFATC4 | Gene | Pathway | associated | 23922006 | ||
| PA31600 | NFKB2 | Gene | Pathway | associated | 23922006 | ||
| PA34321 | REL | Gene | Pathway | associated | 23922006 | ||
| PA34322 | RELB | Gene | Pathway | associated | 23922006 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37660994 | 2024 | LINC-PINT suppresses breast cancer cell proliferation and migration via MEIS2/PPP3CC/NF-κB pathway by sponging miR-576-5p. | 0 |
| 37660994 | 2024 | LINC-PINT suppresses breast cancer cell proliferation and migration via MEIS2/PPP3CC/NF-κB pathway by sponging miR-576-5p. | 0 |
| 33393109 | 2021 | Calcineurin A gamma and NFATc3/SRPX2 axis contribute to human embryonic stem cell differentiation. | 6 |
| 34573382 | 2021 | Calcineurin Gamma Catalytic Subunit PPP3CC Inhibition by miR-200c-3p Affects Apoptosis in Epithelial Ovarian Cancer. | 4 |
| 33393109 | 2021 | Calcineurin A gamma and NFATc3/SRPX2 axis contribute to human embryonic stem cell differentiation. | 6 |
| 34573382 | 2021 | Calcineurin Gamma Catalytic Subunit PPP3CC Inhibition by miR-200c-3p Affects Apoptosis in Epithelial Ovarian Cancer. | 4 |
| 29275364 | 2018 | Genetic Variations in the 3'-untranslated Regions of Genes Involved in the Cell Cycle and Apoptosis Pathways Affect Bladder Cancer Risk. | 3 |
| 29294030 | 2018 | Repression of the expression of PPP3CC by ZEB1 confers activation of NF-κB and contributes to invasion and growth in glioma cells. | 10 |
| 29275364 | 2018 | Genetic Variations in the 3'-untranslated Regions of Genes Involved in the Cell Cycle and Apoptosis Pathways Affect Bladder Cancer Risk. | 3 |
| 29294030 | 2018 | Repression of the expression of PPP3CC by ZEB1 confers activation of NF-κB and contributes to invasion and growth in glioma cells. | 10 |
| 27225880 | 2017 | Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury. | 6 |
| 27225880 | 2017 | Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury. | 6 |
| 26627835 | 2016 | Calcineurin Aγ is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis. | 14 |
| 26627835 | 2016 | Calcineurin Aγ is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis. | 14 |
| 24709691 | 2014 | PPP3CC gene: a putative modulator of antidepressant response through the B-cell receptor signaling pathway. | 13 |
Citation
Dessen P
PPP3CC (protein phosphatase 3 catalytic subunit gamma)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47268/ppp3cc
