PRKAR1B (protein kinase, cAMP-dependent, regulatory, type I, beta)

Identity

Other names	PRKAR1
HGNC	PRKAR1B
Location	7pter-p22
Location_base_pair	Starts at 555913 and ends at 718659 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PRKAR1B   9390
Entrez_Gene	PRKAR1B  5575  protein kinase, cAMP-dependent, regulatory, type I, beta
	Cards
GeneCards	PRKAR1B
Ensembl	ENSG00000188191 [Gene_View]  PRKAR1B [Vega]
Genatlas	PRKAR1B
	Genomic and cartography
GoldenPath	PRKAR1B  -     chr7:555913-718659 -  7p22.3   [Description]    (hg18-March_2006)
Ensembl	PRKAR1B - 7p22.3 [CytoView]
NCBI	Mapview
OMIM	176911 Disease map [OMIM]
HomoloGene	PRKAR1B
	Gene and transcription
Genbank	AK098822 [ ENTREZ ]
Genbank	AK289464 [ ENTREZ ]
Genbank	AK297337 [ ENTREZ ]
Genbank	AL833563 [ ENTREZ ]
Genbank	BC013368 [ ENTREZ ]
RefSeq	NM_002735 [ SRS ]    NM_002735 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001838998 [ SRS ]    NW_001838998 [ ENTREZ ]
RefSeq	NW_923206 [ SRS ]    NW_923206 [ ENTREZ ]
CCDS	PRKAR1B CCDS - NCBI
AceView	PRKAR1B AceView - NCBI
Unigene	Hs.520851 [ SRS ]    Hs.520851 [ NCBI ]
	Protein : pattern, domain, 3D structure
SwissProt	P31321 [ SRS]    P31321 [ EXPASY ]     P31321 [ INTERPRO ]     P31321 [ UNIPROT ] P31321 [ VarSplice FASTA ]
Prosite	PS00888 CNMP_BINDING_1 [ SRS ]    PS00888 CNMP_BINDING_1 [ Expasy ]
Prosite	PS00889 CNMP_BINDING_2 [ SRS ]    PS00889 CNMP_BINDING_2 [ Expasy ]
Prosite	PS50042 CNMP_BINDING_3 [ SRS ]    PS50042 CNMP_BINDING_3 [ Expasy ]
Interpro	IPR003117 cAMP-dep_prot_kin_reg_I/II_a/b [ SRS ]    IPR003117 cAMP-dep_prot_kin_reg_I/II_a/b [ EBI ]
Interpro	IPR002373 cAMP/cGMP_kin [ SRS ]    IPR002373 cAMP/cGMP_kin [ EBI ]
Interpro	IPR000595 cNMP_bd [ SRS ]    IPR000595 cNMP_bd [ EBI ]
Interpro	IPR012198 PK_regulatory [ SRS ]    IPR012198 PK_regulatory [ EBI ]
Interpro	IPR014710 RmlC-like_jellyroll [ SRS ]    IPR014710 RmlC-like_jellyroll [ EBI ]
CluSTr	P31321
Pfam	PF00027 cNMP_binding [ SRS ]    PF00027 cNMP_binding [ Sanger ]    pfam00027 [ NCBI-CDD ]
Pfam	PF02197 RIIa [ SRS ]    PF02197 RIIa [ Sanger ]    pfam02197 [ NCBI-CDD ]
Smart	SM00100 cNMP [EMBL]
Smart	SM00394 RIIa [EMBL]
Blocks	P31321
HPRD	01485
	Protein Interaction databases
DIP	P31321
IntAct	P31321
	Polymorphism : SNP, mutations, diseases
OMIM	176911    [ map ]
GENETests	176911
SNP	PRKAR1B [dbSNP-NCBI]
SNP	NM_002735 [SNP-NCI]
SNP	PRKAR1B [GeneSNPs - Utah]  PRKAR1B] [HGBASE - SRS]
HAPMAP	PRKAR1B [HAPMAP]
HGMD	PRKAR1B
Genetic Association	PRKAR1B
CDC HuGE	PRKAR1B
	General knowledge
Family Browser	PRKAR1B [UCSC Family Browser]
SOURCE	NM_002735
SMD	Hs.520851
SAGE	Hs.520851
GO	nucleotide binding [Amigo]  nucleotide binding
GO	regulation of protein amino acid phosphorylation [Amigo]  regulation of protein amino acid phosphorylation
GO	cAMP-dependent protein kinase complex [Amigo]  cAMP-dependent protein kinase complex
GO	cAMP-dependent protein kinase complex [Amigo]  cAMP-dependent protein kinase complex
GO	signal transduction [Amigo]  signal transduction
GO	cAMP-dependent protein kinase regulator activity [Amigo]  cAMP-dependent protein kinase regulator activity
GO	cAMP-dependent protein kinase regulator activity [Amigo]  cAMP-dependent protein kinase regulator activity
GO	hormone-mediated signaling [Amigo]  hormone-mediated signaling
GO	kinase activity [Amigo]  kinase activity
GO	cAMP binding [Amigo]  cAMP binding
BIOCARTA	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor    [Genes]
BIOCARTA	GATA3 participate in activating the Th2 cytokine genes expression    [Genes]
BIOCARTA	Attenuation of GPCR Signaling    [Genes]
BIOCARTA	Regulation of BAD phosphorylation    [Genes]
BIOCARTA	Transcription Regulation by Methyltransferase of CARM1    [Genes]
BIOCARTA	Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway    [Genes]
BIOCARTA	ChREBP regulation by carbohydrates and cAMP    [Genes]
BIOCARTA	Regulation of ck1/cdk5 by type 1 glutamate receptors    [Genes]
BIOCARTA	Transcription factor CREB and its extracellular signals    [Genes]
BIOCARTA	Repression of Pain Sensation by the Transcriptional Regulator DREAM    [Genes]
BIOCARTA	Signaling Pathway from G-Protein Families    [Genes]
BIOCARTA	Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation    [Genes]
BIOCARTA	mCalpain and friends in Cell motility    [Genes]
BIOCARTA	How Progesterone Initiates the Oocyte Maturation    [Genes]
BIOCARTA	NFAT and Hypertrophy of the heart (Transcription in the broken heart)    [Genes]
BIOCARTA	Actions of Nitric Oxide in the Heart    [Genes]
BIOCARTA	Nitric Oxide Signaling Pathway    [Genes]
BIOCARTA	Phospholipase C-epsilon pathway    [Genes]
BIOCARTA	Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)    [Genes]
BIOCARTA	Sonic Hedgehog (Shh) Pathway    [Genes]
BIOCARTA	Stathmin and breast cancer resistance to antimicrotubule agents    [Genes]
BIOCARTA	Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells    [Genes]
KEGG	Apoptosis
KEGG	Insulin signaling pathway
PubGene	PRKAR1B
TreeFam	PRKAR1B
CTD	5575 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PRKAR1B Related clones (RZPD - Berlin)
	PubMed
PubMed	23 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:03:13 2008