PRKCQ (protein kinase C, theta)

Identity

Other names	MGC126514
	MGC141919
	PRKCT
	nPKC-theta
HGNC	PRKCQ
Location	10p15
Location_base_pair	Starts at 6509111 and ends at 6662244 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PRKCQ   9410
Entrez_Gene	PRKCQ  5588  protein kinase C, theta
	Cards
GeneCards	PRKCQ
Ensembl	ENSG00000065675 [Gene_View]  PRKCQ [Vega]
Genatlas	PRKCQ
	Genomic and cartography
GoldenPath	PRKCQ  -  10p15   chr10:6509111-6662244 -  10p15.1   [Description]    (hg18-March_2006)
Ensembl	PRKCQ - 10p15.1 [CytoView]
NCBI	Mapview
OMIM	600448 Disease map [OMIM]
HomoloGene	PRKCQ
	Gene and transcription
Genbank	AI570478 [ ENTREZ ]
Genbank	AK293935 [ ENTREZ ]
Genbank	AK308099 [ ENTREZ ]
Genbank	AK312411 [ ENTREZ ]
Genbank	AU099414 [ ENTREZ ]
RefSeq	NM_006257 [ SRS ]    NM_006257 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_077569 [ SRS ]    NT_077569 [ ENTREZ ]
RefSeq	NW_001837931 [ SRS ]    NW_001837931 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
CCDS	PRKCQ CCDS - NCBI
AceView	PRKCQ AceView - NCBI
Unigene	Hs.498570 [ SRS ]    Hs.498570 [ NCBI ]
Fast-db	1732 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q04759 [ SRS]    Q04759 [ EXPASY ]     Q04759 [ INTERPRO ]     Q04759 [ UNIPROT ] Q04759 [ VarSplice FASTA ]
Prosite	PS51285 AGC_KINASE_CTER [ SRS ]    PS51285 AGC_KINASE_CTER [ Expasy ]
Prosite	PS50004 C2 [ SRS ]    PS50004 C2 [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR000008 C2_Ca-dep [ SRS ]    IPR000008 C2_Ca-dep [ EBI ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR015745 PKC [ SRS ]    IPR015745 PKC [ EBI ]
Interpro	IPR000961 Pkinase_C [ SRS ]    IPR000961 Pkinase_C [ EBI ]
Interpro	IPR014376 Prot_kin_PKC_delta [ SRS ]    IPR014376 Prot_kin_PKC_delta [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q04759
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Pfam	PF00433 Pkinase_C [ SRS ]    PF00433 Pkinase_C [ Sanger ]    pfam00433 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00133 S_TK_X [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q04759 KPCT_HUMAN [ Domain structure ]   Q04759 KPCT_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q04759
PDB	1XJD [ SRS ]    1XJD [ PdbSum ],   1XJD [ IMB ]   1XJD [ RSDB ]
PDB	2ENJ [ SRS ]    2ENJ [ PdbSum ],   2ENJ [ IMB ]   2ENJ [ RSDB ]
PDB	2ENN [ SRS ]    2ENN [ PdbSum ],   2ENN [ IMB ]   2ENN [ RSDB ]
PDB	2ENZ [ SRS ]    2ENZ [ PdbSum ],   2ENZ [ IMB ]   2ENZ [ RSDB ]
PDB	2JED [ SRS ]    2JED [ PdbSum ],   2JED [ IMB ]   2JED [ RSDB ]
HPRD	02710
	Protein Interaction databases
DIP	Q04759
IntAct	Q04759
	Polymorphism : SNP, mutations, diseases
OMIM	600448    [ map ]
GENETests	600448
SNP	PRKCQ [dbSNP-NCBI]
SNP	NM_006257 [SNP-NCI]
SNP	PRKCQ [GeneSNPs - Utah]  PRKCQ] [HGBASE - SRS]
HAPMAP	PRKCQ [HAPMAP]
COSMIC	PRKCQ [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PRKCQ
Genetic Association	PRKCQ
CDC HuGE	PRKCQ
	General knowledge
Family Browser	PRKCQ [UCSC Family Browser]
SOURCE	NM_006257
SMD	Hs.498570
SAGE	Hs.498570
Enzyme	2.7.11.13 [ Enzyme-Expasy ]   2.7.11.13 [ Enzyme-SRS ]   2.7.11.13 [ IntEnz-EBI ]   2.7.11.13 [ BRENDA ]   2.7.11.13 [ KEGG ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	regulation of cell growth [Amigo]  regulation of cell growth
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein kinase C activity [Amigo]  protein kinase C activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	ATP binding [Amigo]  ATP binding
GO	intracellular [Amigo]  intracellular
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	zinc ion binding [Amigo]  zinc ion binding
GO	transferase activity [Amigo]  transferase activity
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	positive regulation of NF-kappaB transcription factor activity [Amigo]  positive regulation of NF-kappaB transcription factor activity
BIOCARTA	Keratinocyte Differentiation    [Genes]
KEGG	Tight junction
KEGG	T cell receptor signaling pathway
KEGG	Adipocytokine signaling pathway
PubGene	PRKCQ
TreeFam	PRKCQ
CTD	5588 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PRKCQ Related clones (RZPD - Berlin)
	PubMed
PubMed	102 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:03:16 2008