PSME1 (proteasome (prosome, macropain) activator subunit 1 (PA28 alpha))

Identity

Other names	IFI5111
	MGC8628
	PA28A
	PA28alpha
	REGalpha
HGNC	PSME1
Location	14q11.2
Location_base_pair	Starts at 23675218 and ends at 23678016 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PSME1   9568
Entrez_Gene	PSME1  5720  proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
	Cards
GeneCards	PSME1
Ensembl	ENSG00000092010 [Gene_View]  PSME1 [Vega]
Genatlas	PSME1
	Genomic and cartography
GoldenPath	PSME1  -  14q11.2   chr14:23675218-23678016 +  14q12   [Description]    (hg18-March_2006)
Ensembl	PSME1 - 14q12 [CytoView]
NCBI	Mapview
OMIM	600654 Disease map [OMIM]
HomoloGene	PSME1
	Gene and transcription
Genbank	AK311490 [ ENTREZ ]
Genbank	AK312211 [ ENTREZ ]
Genbank	BC000352 [ ENTREZ ]
Genbank	BC007503 [ ENTREZ ]
Genbank	BT019337 [ ENTREZ ]
RefSeq	NM_006263 [ SRS ]    NM_006263 [ ENTREZ ]
RefSeq	NM_176783 [ SRS ]    NM_176783 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
CCDS	PSME1 CCDS - NCBI
AceView	PSME1 AceView - NCBI
Unigene	Hs.75348 [ SRS ]    Hs.75348 [ NCBI ]
Fast-db	94 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q06323 [ SRS]    Q06323 [ EXPASY ]     Q06323 [ INTERPRO ]     Q06323 [ UNIPROT ] Q06323 [ VarSplice FASTA ]
Interpro	IPR003185 Proteasome_activ_REG_asu [ SRS ]    IPR003185 Proteasome_activ_REG_asu [ EBI ]
Interpro	IPR009077 Proteasome_activ_REG_asu/bsu [ SRS ]    IPR009077 Proteasome_activ_REG_asu/bsu [ EBI ]
Interpro	IPR003186 Proteasome_activ_REG_bsu [ SRS ]    IPR003186 Proteasome_activ_REG_bsu [ EBI ]
CluSTr	Q06323
Pfam	PF02251 PA28_alpha [ SRS ]    PF02251 PA28_alpha [ Sanger ]    pfam02251 [ NCBI-CDD ]
Pfam	PF02252 PA28_beta [ SRS ]    PF02252 PA28_beta [ Sanger ]    pfam02252 [ NCBI-CDD ]
Blocks	Q06323
PDB	1AVO [ SRS ]    1AVO [ PdbSum ],   1AVO [ IMB ]   1AVO [ RSDB ]
HPRD	02803
	Protein Interaction databases
DIP	Q06323
IntAct	Q06323
	Polymorphism : SNP, mutations, diseases
OMIM	600654    [ map ]
GENETests	600654
SNP	PSME1 [dbSNP-NCBI]
SNP	NM_006263 [SNP-NCI]
SNP	NM_176783 [SNP-NCI]
SNP	PSME1 [GeneSNPs - Utah]  PSME1] [HGBASE - SRS]
HAPMAP	PSME1 [HAPMAP]
HGMD	PSME1
Genetic Association	PSME1
CDC HuGE	PSME1
	General knowledge
Family Browser	PSME1 [UCSC Family Browser]
SOURCE	NM_006263
SOURCE	NM_176783
SMD	Hs.75348
SAGE	Hs.75348
GO	proteasome complex [Amigo]  proteasome complex
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	proteasome activator complex [Amigo]  proteasome activator complex
GO	proteasome activator activity [Amigo]  proteasome activator activity
GO	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [Amigo]  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Amigo]  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Amigo]  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
KEGG	Antigen processing and presentation
PubGene	PSME1
TreeFam	PSME1
CTD	5720 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PSME1 Related clones (RZPD - Berlin)
	PubMed
PubMed	54 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:03:48 2008