PTBP1 (polypyrimidine tract binding protein 1)

Identity

Other names	HNRNP-I
	HNRNPI
	HNRPI
	MGC10830
	MGC8461
	PTB
	PTB-1
	PTB-T
	PTB2
	PTB3
	PTB4
	pPTB
HGNC	PTBP1
Location	19p13.3
Location_base_pair	Starts at 748411 and ends at 763327 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PTBP1   9583
Entrez_Gene	PTBP1  5725  polypyrimidine tract binding protein 1
	Cards
GeneCards	PTBP1
Ensembl	ENSG00000011304 [Gene_View]  PTBP1 [Vega]
Genatlas	PTBP1
	Genomic and cartography
GoldenPath	PTBP1  -  19p13.3   chr19:748411-763327 +  19p13.3   [Description]    (hg18-March_2006)
Ensembl	PTBP1 - 19p13.3 [CytoView]
NCBI	Mapview
OMIM	600693 Disease map [OMIM]
HomoloGene	PTBP1
	Gene and transcription
Genbank	AB208910 [ ENTREZ ]
Genbank	BC002397 [ ENTREZ ]
Genbank	BC004383 [ ENTREZ ]
Genbank	BC013694 [ ENTREZ ]
Genbank	BC023219 [ ENTREZ ]
RefSeq	NM_002819 [ SRS ]    NM_002819 [ ENTREZ ]
RefSeq	NM_031990 [ SRS ]    NM_031990 [ ENTREZ ]
RefSeq	NM_031991 [ SRS ]    NM_031991 [ ENTREZ ]
RefSeq	NM_175847 [ SRS ]    NM_175847 [ ENTREZ ]
RefSeq	AC_000062 [ SRS ]    AC_000062 [ ENTREZ ]
RefSeq	AC_000151 [ SRS ]    AC_000151 [ ENTREZ ]
RefSeq	NC_000019 [ SRS ]    NC_000019 [ ENTREZ ]
RefSeq	NT_011255 [ SRS ]    NT_011255 [ ENTREZ ]
RefSeq	NW_001838476 [ SRS ]    NW_001838476 [ ENTREZ ]
RefSeq	NW_927140 [ SRS ]    NW_927140 [ ENTREZ ]
CCDS	PTBP1 CCDS - NCBI
AceView	PTBP1 AceView - NCBI
Unigene	Hs.172550 [ SRS ]    Hs.172550 [ NCBI ]
Fast-db	588 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P26599 [ SRS]    P26599 [ EXPASY ]     P26599 [ INTERPRO ]     P26599 [ UNIPROT ] P26599 [ VarSplice FASTA ]
Prosite	PS50102 RRM [ SRS ]    PS50102 RRM [ Expasy ]
Interpro	IPR012677 a_b_plait_nuc_bd [ SRS ]    IPR012677 a_b_plait_nuc_bd [ EBI ]
Interpro	IPR006536 HnRNP-L_PTB [ SRS ]    IPR006536 HnRNP-L_PTB [ EBI ]
Interpro	IPR000504 RRM_RNP1 [ SRS ]    IPR000504 RRM_RNP1 [ EBI ]
CluSTr	P26599
Pfam	PF00076 RRM_1 [ SRS ]    PF00076 RRM_1 [ Sanger ]    pfam00076 [ NCBI-CDD ]
Smart	SM00360 RRM [EMBL]
Blocks	P26599
PDB	1QM9 [ SRS ]    1QM9 [ PdbSum ],   1QM9 [ IMB ]   1QM9 [ RSDB ]
PDB	1SJQ [ SRS ]    1SJQ [ PdbSum ],   1SJQ [ IMB ]   1SJQ [ RSDB ]
PDB	1SJR [ SRS ]    1SJR [ PdbSum ],   1SJR [ IMB ]   1SJR [ RSDB ]
PDB	2AD9 [ SRS ]    2AD9 [ PdbSum ],   2AD9 [ IMB ]   2AD9 [ RSDB ]
PDB	2ADB [ SRS ]    2ADB [ PdbSum ],   2ADB [ IMB ]   2ADB [ RSDB ]
PDB	2ADC [ SRS ]    2ADC [ PdbSum ],   2ADC [ IMB ]   2ADC [ RSDB ]
PDB	2EVZ [ SRS ]    2EVZ [ PdbSum ],   2EVZ [ IMB ]   2EVZ [ RSDB ]
HPRD	02823
	Protein Interaction databases
DIP	P26599
IntAct	P26599
	Polymorphism : SNP, mutations, diseases
OMIM	600693    [ map ]
GENETests	600693
SNP	PTBP1 [dbSNP-NCBI]
SNP	NM_002819 [SNP-NCI]
SNP	NM_031990 [SNP-NCI]
SNP	NM_031991 [SNP-NCI]
SNP	NM_175847 [SNP-NCI]
SNP	PTBP1 [GeneSNPs - Utah]  PTBP1] [HGBASE - SRS]
HAPMAP	PTBP1 [HAPMAP]
COSMIC	PTBP1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PTBP1
Genetic Association	PTBP1
CDC HuGE	PTBP1
	General knowledge
Family Browser	PTBP1 [UCSC Family Browser]
SOURCE	NM_002819
SOURCE	NM_031990
SOURCE	NM_031991
SOURCE	NM_175847
SMD	Hs.172550
SAGE	Hs.172550
GO	nucleotide binding [Amigo]  nucleotide binding
GO	nuclear mRNA splicing, via spliceosome [Amigo]  nuclear mRNA splicing, via spliceosome
GO	nucleic acid binding [Amigo]  nucleic acid binding
GO	RNA binding [Amigo]  RNA binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	nucleolus [Amigo]  nucleolus
GO	mRNA processing [Amigo]  mRNA processing
GO	poly-pyrimidine tract binding [Amigo]  poly-pyrimidine tract binding
GO	RNA splicing [Amigo]  RNA splicing
GO	heterogeneous nuclear ribonucleoprotein complex [Amigo]  heterogeneous nuclear ribonucleoprotein complex
BIOCARTA	Internal Ribosome entry pathway    [Genes]
PubGene	PTBP1
TreeFam	PTBP1
CTD	5725 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PTBP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	60 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:03:50 2008