RAB5A (RAB5A, member RAS oncogene family)

Identity

Other names	RAB5
HGNC	RAB5A
Location	3p24-p22
Location_base_pair	Starts at 19963763 and ends at 20001647 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RAB5A   9783
Entrez_Gene	RAB5A  5868  RAB5A, member RAS oncogene family
	Cards
GeneCards	RAB5A
Ensembl	ENSG00000144566 [Gene_View]  RAB5A [Vega]
Genatlas	RAB5A
	Genomic and cartography
GoldenPath	RAB5A  -     chr3:19963763-20001647 +  3p24.3   [Description]    (hg18-March_2006)
Ensembl	RAB5A - 3p24.3 [CytoView]
NCBI	Mapview
OMIM	179512 Disease map [OMIM]
HomoloGene	RAB5A
	Gene and transcription
Genbank	AF464088 [ ENTREZ ]
Genbank	AF498936 [ ENTREZ ]
Genbank	AK295992 [ ENTREZ ]
Genbank	AK309287 [ ENTREZ ]
Genbank	AK312618 [ ENTREZ ]
RefSeq	NM_004162 [ SRS ]    NM_004162 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838877 [ SRS ]    NW_001838877 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
CCDS	RAB5A CCDS - NCBI
AceView	RAB5A AceView - NCBI
Unigene	Hs.475663 [ SRS ]    Hs.475663 [ NCBI ]
Fast-db	2951 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P20339 [ SRS]    P20339 [ EXPASY ]     P20339 [ INTERPRO ]     P20339 [ UNIPROT ] P20339 [ VarSplice FASTA ]
Interpro	IPR003579 GTPase_Rab [ SRS ]    IPR003579 GTPase_Rab [ EBI ]
Interpro	IPR015599 Rab5_like [ SRS ]    IPR015599 Rab5_like [ EBI ]
Interpro	IPR013753 Ras [ SRS ]    IPR013753 Ras [ EBI ]
Interpro	IPR001806 Ras_trnsfrmng [ SRS ]    IPR001806 Ras_trnsfrmng [ EBI ]
Interpro	IPR005225 Small_GTP_bd [ SRS ]    IPR005225 Small_GTP_bd [ EBI ]
CluSTr	P20339
Pfam	PF00071 Ras [ SRS ]    PF00071 Ras [ Sanger ]    pfam00071 [ NCBI-CDD ]
Smart	SM00175 RAB [EMBL]
Blocks	P20339
PDB	1N6H [ SRS ]    1N6H [ PdbSum ],   1N6H [ IMB ]   1N6H [ RSDB ]
PDB	1N6I [ SRS ]    1N6I [ PdbSum ],   1N6I [ IMB ]   1N6I [ RSDB ]
PDB	1N6K [ SRS ]    1N6K [ PdbSum ],   1N6K [ IMB ]   1N6K [ RSDB ]
PDB	1N6L [ SRS ]    1N6L [ PdbSum ],   1N6L [ IMB ]   1N6L [ RSDB ]
PDB	1N6N [ SRS ]    1N6N [ PdbSum ],   1N6N [ IMB ]   1N6N [ RSDB ]
PDB	1N6O [ SRS ]    1N6O [ PdbSum ],   1N6O [ IMB ]   1N6O [ RSDB ]
PDB	1N6P [ SRS ]    1N6P [ PdbSum ],   1N6P [ IMB ]   1N6P [ RSDB ]
PDB	1N6R [ SRS ]    1N6R [ PdbSum ],   1N6R [ IMB ]   1N6R [ RSDB ]
PDB	1R2Q [ SRS ]    1R2Q [ PdbSum ],   1R2Q [ IMB ]   1R2Q [ RSDB ]
PDB	1TU3 [ SRS ]    1TU3 [ PdbSum ],   1TU3 [ IMB ]   1TU3 [ RSDB ]
PDB	1TU4 [ SRS ]    1TU4 [ PdbSum ],   1TU4 [ IMB ]   1TU4 [ RSDB ]
HPRD	01542
	Protein Interaction databases
DIP	P20339
IntAct	P20339
	Polymorphism : SNP, mutations, diseases
OMIM	179512    [ map ]
GENETests	179512
SNP	RAB5A [dbSNP-NCBI]
SNP	NM_004162 [SNP-NCI]
SNP	RAB5A [GeneSNPs - Utah]  RAB5A] [HGBASE - SRS]
HAPMAP	RAB5A [HAPMAP]
COSMIC	RAB5A [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RAB5A
Genetic Association	RAB5A
CDC HuGE	RAB5A
	General knowledge
Family Browser	RAB5A [UCSC Family Browser]
SOURCE	NM_004162
SMD	Hs.475663
SAGE	Hs.475663
GO	nucleotide binding [Amigo]  nucleotide binding
GO	ruffle [Amigo]  ruffle
GO	GTPase activity [Amigo]  GTPase activity
GO	protein binding [Amigo]  protein binding
GO	protein binding [Amigo]  protein binding
GO	GTP binding [Amigo]  GTP binding
GO	plasma membrane [Amigo]  plasma membrane
GO	endocytosis [Amigo]  endocytosis
GO	small GTPase mediated signal transduction [Amigo]  small GTPase mediated signal transduction
GO	protein transport [Amigo]  protein transport
GO	guanyl nucleotide binding [Amigo]  guanyl nucleotide binding
GO	endocytic vesicle [Amigo]  endocytic vesicle
GO	early endosome membrane [Amigo]  early endosome membrane
GO	melanosome [Amigo]  melanosome
GO	membrane raft [Amigo]  membrane raft
BIOCARTA	The role of FYVE-finger proteins in vesicle transport    [Genes]
BIOCARTA	Phosphoinositides and their downstream targets.    [Genes]
BIOCARTA	Rab GTPases Mark Targets In The Endocytotic Machinery    [Genes]
PubGene	RAB5A
TreeFam	RAB5A
CTD	5868 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RAB5A Related clones (RZPD - Berlin)
	PubMed
PubMed	61 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:04:38 2008