RAPGEF5 (Rap guanine nucleotide exchange factor (GEF) 5)

Identity

Other names	GFR
	KIAA0277
	MR-GEF
	REPAC
HGNC	RAPGEF5
Location	7p15.3
Location_base_pair	Starts at 22124433 and ends at 22363058 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	RAPGEF5   16862
Entrez_Gene	RAPGEF5  9771  Rap guanine nucleotide exchange factor (GEF) 5
	Cards
GeneCards	RAPGEF5
Ensembl	ENSG00000101265 [Gene_View]  RAPGEF5 [Vega]
Genatlas	RAPGEF5
	Genomic and cartography
GoldenPath	RAPGEF5  -  7p15.3   chr7:22124433-22363058 -  7p15.3   [Description]    (hg18-March_2006)
Ensembl	RAPGEF5 - 7p15.3 [CytoView]
NCBI	Mapview
OMIM	609527 Disease map [OMIM]
HomoloGene	RAPGEF5
	Gene and transcription
Genbank	AA732485 [ ENTREZ ]
Genbank	AA815190 [ ENTREZ ]
Genbank	AA890636 [ ENTREZ ]
Genbank	AL833195 [ ENTREZ ]
Genbank	AW511225 [ ENTREZ ]
RefSeq	NM_012294 [ SRS ]    NM_012294 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001839003 [ SRS ]    NW_001839003 [ ENTREZ ]
RefSeq	NW_923240 [ SRS ]    NW_923240 [ ENTREZ ]
CCDS	RAPGEF5 CCDS - NCBI
AceView	RAPGEF5 AceView - NCBI
Unigene	Hs.713627 [ SRS ]    Hs.713627 [ NCBI ]
Fast-db	2685 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q5JPD2 [ SRS]    Q5JPD2 [ EXPASY ]     Q5JPD2 [ INTERPRO ]     Q5JPD2 [ UNIPROT ] Q5JPD2 [ VarSplice FASTA ]
Interpro	IPR008937 Ras_GEF [ SRS ]    IPR008937 Ras_GEF [ EBI ]
Interpro	IPR011991 Wing_hlx_DNA_bd [ SRS ]    IPR011991 Wing_hlx_DNA_bd [ EBI ]
CluSTr	Q5JPD2
Blocks	Q5JPD2
HPRD	15208
	Protein Interaction databases
DIP	Q5JPD2
IntAct	Q5JPD2
	Polymorphism : SNP, mutations, diseases
OMIM	609527    [ map ]
GENETests	609527
SNP	RAPGEF5 [dbSNP-NCBI]
SNP	NM_012294 [SNP-NCI]
SNP	RAPGEF5 [GeneSNPs - Utah]  RAPGEF5] [HGBASE - SRS]
HAPMAP	RAPGEF5 [HAPMAP]
COSMIC	RAPGEF5 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RAPGEF5
Genetic Association	RAPGEF5
CDC HuGE	RAPGEF5
	General knowledge
Family Browser	RAPGEF5 [UCSC Family Browser]
SOURCE	NM_012294
SMD	Hs.713627
SAGE	Hs.713627
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	small GTPase mediated signal transduction [Amigo]  small GTPase mediated signal transduction
GO	nervous system development [Amigo]  nervous system development
GO	Rap guanyl-nucleotide exchange factor activity [Amigo]  Rap guanyl-nucleotide exchange factor activity
GO	GTP-dependent protein binding [Amigo]  GTP-dependent protein binding
GO	regulation of small GTPase mediated signal transduction [Amigo]  regulation of small GTPase mediated signal transduction
BIOCARTA	Ghrelin: Regulation of Food Intake and Energy Homeostasis    [Genes]
PubGene	RAPGEF5
TreeFam	RAPGEF5
CTD	9771 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RAPGEF5 Related clones (RZPD - Berlin)
	PubMed
PubMed	9 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:05:05 2008