RIPK3 (receptor-interacting serine-threonine kinase 3)

Identity

Other names	RIP3
HGNC	RIPK3
Location	14q12
Location_base_pair	Starts at 23875067 and ends at 23879082 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RIPK3   10021
Entrez_Gene	RIPK3  11035  receptor-interacting serine-threonine kinase 3
	Cards
GeneCards	RIPK3
Ensembl	ENSG00000129465 [Gene_View]  RIPK3 [Vega]
Genatlas	RIPK3
	Genomic and cartography
GoldenPath	RIPK3  -  14q12   chr14:23875067-23879082 -  14q12   [Description]    (hg18-March_2006)
Ensembl	RIPK3 - 14q12 [CytoView]
NCBI	Mapview
OMIM	605817 Disease map [OMIM]
HomoloGene	RIPK3
	Gene and transcription
Genbank	AF156884 [ ENTREZ ]
Genbank	AK075275 [ ENTREZ ]
Genbank	AK296140 [ ENTREZ ]
Genbank	AY453693 [ ENTREZ ]
Genbank	AY494982 [ ENTREZ ]
RefSeq	NM_006871 [ SRS ]    NM_006871 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
CCDS	RIPK3 CCDS - NCBI
AceView	RIPK3 AceView - NCBI
Unigene	Hs.268551 [ SRS ]    Hs.268551 [ NCBI ]
Fast-db	113 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q5J795 [ SRS]    Q5J795 [ EXPASY ]     Q5J795 [ INTERPRO ]     Q5J795 [ UNIPROT ] Q5J795 [ VarSplice FASTA ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
CluSTr	Q5J795
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q5J795 Q5J795_HUMAN [ Domain structure ]   Q5J795 Q5J795_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q5J795
HPRD	09315
	Protein Interaction databases
DIP	Q5J795
IntAct	Q5J795
	Polymorphism : SNP, mutations, diseases
OMIM	605817    [ map ]
GENETests	605817
SNP	RIPK3 [dbSNP-NCBI]
SNP	NM_006871 [SNP-NCI]
SNP	RIPK3 [GeneSNPs - Utah]  RIPK3] [HGBASE - SRS]
HAPMAP	RIPK3 [HAPMAP]
COSMIC	RIPK3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RIPK3
Genetic Association	RIPK3
CDC HuGE	RIPK3
	General knowledge
Family Browser	RIPK3 [UCSC Family Browser]
SOURCE	NM_006871
SMD	Hs.268551
SAGE	Hs.268551
GO	nucleotide binding [Amigo]  nucleotide binding
GO	transcription coactivator activity [Amigo]  transcription coactivator activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein tyrosine kinase activity [Amigo]  protein tyrosine kinase activity
GO	receptor activity [Amigo]  receptor activity
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	protein modification process [Amigo]  protein modification process
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	apoptosis [Amigo]  apoptosis
GO	signal transduction [Amigo]  signal transduction
GO	induction of apoptosis by extracellular signals [Amigo]  induction of apoptosis by extracellular signals
GO	transferase activity [Amigo]  transferase activity
PubGene	RIPK3
TreeFam	RIPK3
CTD	11035 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RIPK3 Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:06:11 2008