RIPK4 (receptor-interacting serine-threonine kinase 4)

Identity

Other names	ANKK2
	ANKRD3
	DIK
	MGC129992
	MGC129993
	PKK
	RIP4
HGNC	RIPK4
Location	21q22.3
Location_base_pair	Starts at 42032598 and ends at 42060318 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	RIPK4   496
Entrez_Gene	RIPK4  54101  receptor-interacting serine-threonine kinase 4
	Cards
GeneCards	RIPK4
Ensembl	ENSG00000183421 [Gene_View]  RIPK4 [Vega]
Genatlas	RIPK4
	Genomic and cartography
GoldenPath	RIPK4  -  21q22.3   chr21:42032598-42060318 -  21q22.3   [Description]    (hg18-March_2006)
Ensembl	RIPK4 - 21q22.3 [CytoView]
NCBI	Mapview
OMIM	605706 Disease map [OMIM]
HomoloGene	RIPK4
	Gene and transcription
Genbank	AB047783 [ ENTREZ ]
Genbank	AF308292 [ ENTREZ ]
Genbank	AJ278016 [ ENTREZ ]
Genbank	AK027424 [ ENTREZ ]
Genbank	AL137448 [ ENTREZ ]
RefSeq	NM_020639 [ SRS ]    NM_020639 [ ENTREZ ]
RefSeq	AC_000064 [ SRS ]    AC_000064 [ ENTREZ ]
RefSeq	AC_000153 [ SRS ]    AC_000153 [ ENTREZ ]
RefSeq	NC_000021 [ SRS ]    NC_000021 [ ENTREZ ]
RefSeq	NT_030188 [ SRS ]    NT_030188 [ ENTREZ ]
RefSeq	NW_001838712 [ SRS ]    NW_001838712 [ ENTREZ ]
RefSeq	NW_927384 [ SRS ]    NW_927384 [ ENTREZ ]
CCDS	RIPK4 CCDS - NCBI
AceView	RIPK4 AceView - NCBI
Unigene	Hs.517310 [ SRS ]    Hs.517310 [ NCBI ]
Fast-db	3171 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P57078 [ SRS]    P57078 [ EXPASY ]     P57078 [ INTERPRO ]     P57078 [ UNIPROT ] P57078 [ VarSplice FASTA ]
Prosite	PS50297 ANK_REP_REGION [ SRS ]    PS50297 ANK_REP_REGION [ Expasy ]
Prosite	PS50088 ANK_REPEAT [ SRS ]    PS50088 ANK_REPEAT [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR002110 ANK [ SRS ]    IPR002110 ANK [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
CluSTr	P57078
Pfam	PF00023 Ank [ SRS ]    PF00023 Ank [ Sanger ]    pfam00023 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00248 ANK [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P57078 RIPK4_HUMAN [ Domain structure ]   P57078 RIPK4_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P57078
HPRD	10419
	Protein Interaction databases
DIP	P57078
IntAct	P57078
	Polymorphism : SNP, mutations, diseases
OMIM	605706    [ map ]
GENETests	605706
SNP	RIPK4 [dbSNP-NCBI]
SNP	NM_020639 [SNP-NCI]
SNP	RIPK4 [GeneSNPs - Utah]  RIPK4] [HGBASE - SRS]
HAPMAP	RIPK4 [HAPMAP]
COSMIC	RIPK4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RIPK4
Genetic Association	RIPK4
CDC HuGE	RIPK4
	General knowledge
Family Browser	RIPK4 [UCSC Family Browser]
SOURCE	NM_020639
SMD	Hs.517310
SAGE	Hs.517310
Enzyme	2.7.11.1 [ Enzyme-Expasy ]   2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	receptor activity [Amigo]  receptor activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	ATP binding [Amigo]  ATP binding
GO	cellular_component [Amigo]  cellular_component
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	membrane [Amigo]  membrane
GO	transferase activity [Amigo]  transferase activity
PubGene	RIPK4
TreeFam	RIPK4
CTD	54101 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RIPK4 Related clones (RZPD - Berlin)
	PubMed
PubMed	11 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:08:54 2008