RNASE2 (ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin))

Identity

Other names	EDN
	RNS2
HGNC	RNASE2
Location	14q24-q31
Location_base_pair	Starts at 20493470 and ends at 20494434 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RNASE2   10045
Entrez_Gene	RNASE2  6036  ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
	Cards
GeneCards	RNASE2
Ensembl	RNASE2 [Search_View]   ENSG00000169385 [Gene_View]
Genatlas	RNASE2
GeneLynx	RNASE2
eGenome	RNASE2
euGene	6036
	Genomic and cartography
GoldenPath	RNASE2  -     chr14:20493470-20494434 +  14q11.2   [Description]    (hg18-March_2006)
Ensembl	RNASE2 - 14q11.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	RNASE2
	Gene and transcription
Genbank	BC093678 [ ENTREZ ]
Genbank	BC093680 [ ENTREZ ]
Genbank	BC096059 [ ENTREZ ]
Genbank	M24157 [ ENTREZ ]
Genbank	M28129 [ ENTREZ ]
RefSeq	NM_002934 [ SRS ]    NM_002934 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
AceView	RNASE2 AceView - NCBI
Unigene	Hs.728 [ SRS ]    Hs.728 [ NCBI ]     HS728 [ spliceNest ]
Fast-db	28 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P10153 [ SRS]    P10153 [ EXPASY ]     P10153 [ INTERPRO ]     P10153 [ UNIPROT ]
Prosite	PS00127 RNASE_PANCREATIC [ SRS ]    PS00127 RNASE_PANCREATIC [ Expasy ]
Interpro	IPR001427 RNaseA [ SRS ]    IPR001427 RNaseA [ EBI ]
CluSTr	P10153
Pfam	PF00074 RnaseA [ SRS ]    PF00074 RnaseA [ Sanger ]    pfam00074 [ NCBI-CDD ]
Smart	SM00092 RNAse_Pc [EMBL]
Prodom	PD000535 RNaseA[INRA-Toulouse]
Prodom	P10153 RNAS2_HUMAN [ Domain structure ]   P10153 RNAS2_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P10153
PDB	1GQV [ SRS ]    1GQV [ PdbSum ],   1GQV [ IMB ]   1GQV [ RSDB ]
PDB	1HI2 [ SRS ]    1HI2 [ PdbSum ],   1HI2 [ IMB ]   1HI2 [ RSDB ]
PDB	1HI3 [ SRS ]    1HI3 [ PdbSum ],   1HI3 [ IMB ]   1HI3 [ RSDB ]
PDB	1HI4 [ SRS ]    1HI4 [ PdbSum ],   1HI4 [ IMB ]   1HI4 [ RSDB ]
PDB	1HI5 [ SRS ]    1HI5 [ PdbSum ],   1HI5 [ IMB ]   1HI5 [ RSDB ]
PDB	1K2A [ SRS ]    1K2A [ PdbSum ],   1K2A [ IMB ]   1K2A [ RSDB ]
PDB	2BEX [ SRS ]    2BEX [ PdbSum ],   2BEX [ IMB ]   2BEX [ RSDB ]
PDB	2BZZ [ SRS ]    2BZZ [ PdbSum ],   2BZZ [ IMB ]   2BZZ [ RSDB ]
PDB	2C01 [ SRS ]    2C01 [ PdbSum ],   2C01 [ IMB ]   2C01 [ RSDB ]
PDB	2C02 [ SRS ]    2C02 [ PdbSum ],   2C02 [ IMB ]   2C02 [ RSDB ]
PDB	2C05 [ SRS ]    2C05 [ PdbSum ],   2C05 [ IMB ]   2C05 [ RSDB ]
HPRD	00577
	Protein Interaction databases
DIP	P10153
IntAct	P10153
	Polymorphism : SNP, mutations, diseases
OMIM	131410    [ map ]
GENECLINICS	131410
SNP	RNASE2 [dbSNP-NCBI]
SNP	NM_002934 [SNP-NCI]
SNP	RNASE2 [GeneSNPs - Utah]  RNASE2] [HGBASE - SRS]
HAPMAP	RNASE2 [HAPMAP]
HGMD	RNASE2
	General knowledge
Family Browser	RNASE2 [UCSC Family Browser]
SOURCE	NM_002934
SMD	Hs.728
SAGE	Hs.728
Enzyme	3.1.27.5 [ Enzyme-Expasy ]   3.1.27.5 [ Enzyme-SRS ]   3.1.27.5 [ IntEnz-EBI ]   3.1.27.5 [ BRENDA ]   3.1.27.5 [ KEGG ]   3.1.27.5 [ WIT ]
GO	nucleic acid binding [Amigo]  nucleic acid binding
GO	endonuclease activity [Amigo]  endonuclease activity
GO	pancreatic ribonuclease activity [Amigo]  pancreatic ribonuclease activity
GO	ribonuclease activity [Amigo]  ribonuclease activity
GO	extracellular region [Amigo]  extracellular region
GO	lysosome [Amigo]  lysosome
GO	RNA catabolic process [Amigo]  RNA catabolic process
GO	chemotaxis [Amigo]  chemotaxis
GO	hydrolase activity [Amigo]  hydrolase activity
PubGene	RNASE2
TreeFam	RNASE2
CTD	6036 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RNASE2 Related clones (RZPD - Berlin)
	PubMed
PubMed	41 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:52:32 2008