RPA1 (replication protein A1, 70kDa)

Identity

Other names	HSSB
	REPA1
	RF-A
	RP-A
	RPA70
HGNC	RPA1
Location	17p13.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RPA1   10289
Entrez_Gene	RPA1  6117  replication protein A1, 70kDa
	Cards
GeneCards	RPA1
Ensembl	RPA1 [Search_View]   ENSG00000132383 [Gene_View]
Genatlas	RPA1
GeneLynx	RPA1
eGenome	RPA1
euGene	6117
	Genomic and cartography
GoldenPath	RPA1  -  17p13.3   chr17:1680023-1749598 +  17p13.3   [Description]    (hg18-March_2006)
Ensembl	RPA1 - 17p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	RPA1
	Gene and transcription
Genbank	AB209732 [ ENTREZ ]
Genbank	AK289704 [ ENTREZ ]
Genbank	BC018126 [ ENTREZ ]
Genbank	CR592316 [ ENTREZ ]
Genbank	CR615851 [ ENTREZ ]
RefSeq	NM_002945 [ SRS ]    NM_002945 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	RPA1 AceView - NCBI
Unigene	Hs.595562 [ SRS ]    Hs.595562 [ NCBI ]     HS595562 [ spliceNest ]
Fast-db	692 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P27694 [ SRS]    P27694 [ EXPASY ]     P27694 [ INTERPRO ]     P27694 [ UNIPROT ]
Interpro	IPR012340 NA-bd_OB-fold [ SRS ]    IPR012340 NA-bd_OB-fold [ EBI ]
Interpro	IPR004365 NA_bd_OB_tRNA-helicase [ SRS ]    IPR004365 NA_bd_OB_tRNA-helicase [ EBI ]
Interpro	IPR007199 Rep-A_N [ SRS ]    IPR007199 Rep-A_N [ EBI ]
Interpro	IPR013955 Rep_factor-A_C [ SRS ]    IPR013955 Rep_factor-A_C [ EBI ]
Interpro	IPR004591 Rpa1 [ SRS ]    IPR004591 Rpa1 [ EBI ]
CluSTr	P27694
Pfam	PF04057 Rep-A_N [ SRS ]    PF04057 Rep-A_N [ Sanger ]    pfam04057 [ NCBI-CDD ]
Pfam	PF08646 Rep_fac-A_C [ SRS ]    PF08646 Rep_fac-A_C [ Sanger ]    pfam08646 [ NCBI-CDD ]
Pfam	PF01336 tRNA_anti [ SRS ]    PF01336 tRNA_anti [ Sanger ]    pfam01336 [ NCBI-CDD ]
Blocks	P27694
PDB	1EWI [ SRS ]    1EWI [ PdbSum ],   1EWI [ IMB ]   1EWI [ RSDB ]
PDB	1FGU [ SRS ]    1FGU [ PdbSum ],   1FGU [ IMB ]   1FGU [ RSDB ]
PDB	1JMC [ SRS ]    1JMC [ PdbSum ],   1JMC [ IMB ]   1JMC [ RSDB ]
PDB	1L1O [ SRS ]    1L1O [ PdbSum ],   1L1O [ IMB ]   1L1O [ RSDB ]
PDB	2B29 [ SRS ]    2B29 [ PdbSum ],   2B29 [ IMB ]   2B29 [ RSDB ]
PDB	2B3G [ SRS ]    2B3G [ PdbSum ],   2B3G [ IMB ]   2B3G [ RSDB ]
HPRD	01565
	Protein Interaction databases
DIP	P27694
IntAct	P27694
	Polymorphism : SNP, mutations, diseases
OMIM	179835    [ map ]
GENECLINICS	179835
SNP	RPA1 [dbSNP-NCBI]
SNP	NM_002945 [SNP-NCI]
SNP	RPA1 [GeneSNPs - Utah]  RPA1] [HGBASE - SRS]
HAPMAP	RPA1 [HAPMAP]
COSMIC	RPA1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RPA1
	General knowledge
Family Browser	RPA1 [UCSC Family Browser]
SOURCE	NM_002945
SMD	Hs.595562
SAGE	Hs.595562
GO	nucleotide-excision repair, DNA damage removal [Amigo]  nucleotide-excision repair, DNA damage removal
GO	condensed chromosome [Amigo]  condensed chromosome
GO	DNA binding [Amigo]  DNA binding
GO	chromatin binding [Amigo]  chromatin binding
GO	single-stranded DNA binding [Amigo]  single-stranded DNA binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	DNA replication factor A complex [Amigo]  DNA replication factor A complex
GO	DNA-dependent DNA replication [Amigo]  DNA-dependent DNA replication
GO	DNA repair [Amigo]  DNA repair
GO	nucleotide-excision repair, DNA gap filling [Amigo]  nucleotide-excision repair, DNA gap filling
GO	DNA recombination [Amigo]  DNA recombination
GO	meiosis [Amigo]  meiosis
GO	zinc ion binding [Amigo]  zinc ion binding
GO	PML body [Amigo]  PML body
GO	metal ion binding [Amigo]  metal ion binding
BIOCARTA	Hypoxia and p53 in the Cardiovascular system    [Genes]
PubGene	RPA1
TreeFam	RPA1
CTD	6117 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RPA1 Related clones (RZPD - Berlin)
	PubMed
PubMed	90 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:30:04 2008