RPS6KA3 (ribosomal protein S6 kinase, 90kDa, polypeptide 3)

Identity

Other names	CLS
	HU-3
	ISPK-1
	MAPKAPK1B
	MRX19
	RSK
	RSK2
	S6K-alpha3
	p90-RSK2
	pp90RSK2
Hugo	RPS6KA3
Location	Xp22.2-p22.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	RPS6KA3
GDB	RPS6KA3
Entrez_Gene	RPS6KA3  6197  ribosomal protein S6 kinase, 90kDa, polypeptide 3
	Cards
GeneCards	RPS6KA3
Ensembl	RPS6KA3 [Search_View]   ENSG00000177189 [Gene_View]
Genatlas	RPS6KA3
GeneLynx	RPS6KA3
eGenome	RPS6KA3
euGene	6197
	Genomic and cartography
GoldenPath	RPS6KA3  -     chrX:20077951-20194671 -  Xp22.12   [Description]    (hg18-March_2006)
Ensembl	RPS6KA3 - Xp22.12 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	RPS6KA3
	Gene and transcription
Genbank	AA317826 [ ENTREZ ]
Genbank	AA858312 [ ENTREZ ]
Genbank	AB102662 [ ENTREZ ]
Genbank	AB208933 [ ENTREZ ]
Genbank	AK022869 [ ENTREZ ]
RefSeq	NM_004586 [ SRS ]    NM_004586 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_011757 [ SRS ]    NT_011757 [ ENTREZ ]
AceView	RPS6KA3 AceView - NCBI
Unigene	Hs.445387 [ SRS ]    Hs.445387 [ NCBI ]     HS445387 [ spliceNest ]
Fast-db	3981 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P51812 [ SRS]    P51812 [ EXPASY ]     P51812 [ INTERPRO ]
Prosite	PS51285 AGC_KINASE_CTER [ SRS ]    PS51285 AGC_KINASE_CTER [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000961 Pkinase_C [ SRS ]    IPR000961 Pkinase_C [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	P51812
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Pfam	PF00433 Pkinase_C [ SRS ]    PF00433 Pkinase_C [ Sanger ]    pfam00433 [ NCBI-CDD ]
Smart	SM00133 S_TK_X [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P51812 KS6A3_HUMAN [ Domain structure ]   P51812 KS6A3_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P51812
HPRD	02092
	Protein Interaction databases
DIP	P51812
IntAct	P51812
	Polymorphism : SNP, mutations, diseases
OMIM	300075;303600    [ map ]
GENECLINICS	300075;303600
SNP	RPS6KA3 [dbSNP-NCBI]
SNP	NM_004586 [SNP-NCI]
SNP	RPS6KA3 [GeneSNPs - Utah]  RPS6KA3] [HGBASE - SRS]
HAPMAP	RPS6KA3 [HAPMAP]
COSMIC	RPS6KA3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RPS6KA3
	General knowledge
Family Browser	RPS6KA3 [UCSC Family Browser]
SOURCE	NM_004586
SMD	Hs.445387
SAGE	Hs.445387
Enzyme	2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ Brenda-SRS ]   2.7.11.1 [ KEGG ]   2.7.11.1 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	skeletal development [Amigo]  skeletal development
GO	protein kinase activity [Amigo]  protein kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	ribosome [Amigo]  ribosome
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	signal transduction [Amigo]  signal transduction
GO	central nervous system development [Amigo]  central nervous system development
GO	transferase activity [Amigo]  transferase activity
BIOCARTA	Signaling Pathway from G-Protein Families    [Genes]
BIOCARTA	MAPKinase Signaling Pathway    [Genes]
KEGG	MAPK signaling pathway
KEGG	mTOR signaling pathway
KEGG	Long-term potentiation
PubGene	RPS6KA3
TreeFam	RPS6KA3
CTD	6197 [Comparative Genomics Database]
	Other databases
	Probes
Probe	RPS6KA3 Related clones (RZPD - Berlin)
	PubMed
PubMed	76 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:27:01 2008