RRM2 (ribonucleotide reductase M2 polypeptide)

Identity

Other names	R2
	RR2M
HGNC	RRM2
Location	2p25-p24
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RRM2   10452
Entrez_Gene	RRM2  6241  ribonucleotide reductase M2 polypeptide
	Cards
GeneCards	RRM2
Ensembl	RRM2 [Search_View]   ENSG00000171848 [Gene_View]
Genatlas	RRM2
GeneLynx	RRM2
eGenome	RRM2
euGene	6241
	Genomic and cartography
GoldenPath	RRM2  -     chr2:10180186-10188074 +  2p25.1   [Description]    (hg18-March_2006)
Ensembl	RRM2 - 2p25.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	RRM2
	Gene and transcription
Genbank	AK092671 [ ENTREZ ]
Genbank	AK123010 [ ENTREZ ]
Genbank	AK313719 [ ENTREZ ]
Genbank	BC001886 [ ENTREZ ]
Genbank	BC028932 [ ENTREZ ]
RefSeq	NM_001034 [ SRS ]    NM_001034 [ ENTREZ ]
RefSeq	AC_000045 [ SRS ]    AC_000045 [ ENTREZ ]
RefSeq	AC_000134 [ SRS ]    AC_000134 [ ENTREZ ]
RefSeq	NC_000002 [ SRS ]    NC_000002 [ ENTREZ ]
RefSeq	NT_005334 [ SRS ]    NT_005334 [ ENTREZ ]
RefSeq	NW_001838766 [ SRS ]    NW_001838766 [ ENTREZ ]
RefSeq	NW_927719 [ SRS ]    NW_927719 [ ENTREZ ]
AceView	RRM2 AceView - NCBI
Unigene	Hs.226390 [ SRS ]    Hs.226390 [ NCBI ]     HS226390 [ spliceNest ]
Fast-db	1260 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P31350 [ SRS]    P31350 [ EXPASY ]     P31350 [ INTERPRO ]     P31350 [ UNIPROT ]
Prosite	PS00368 RIBORED_SMALL [ SRS ]    PS00368 RIBORED_SMALL [ Expasy ]
Interpro	IPR012348 Ribncl_red_rel [ SRS ]    IPR012348 Ribncl_red_rel [ EBI ]
Interpro	IPR000358 Ribonucl_redctse [ SRS ]    IPR000358 Ribonucl_redctse [ EBI ]
CluSTr	P31350
Pfam	PF00268 Ribonuc_red_sm [ SRS ]    PF00268 Ribonuc_red_sm [ Sanger ]    pfam00268 [ NCBI-CDD ]
Blocks	P31350
PDB	2UW2 [ SRS ]    2UW2 [ PdbSum ],   2UW2 [ IMB ]   2UW2 [ RSDB ]
HPRD	01587
	Protein Interaction databases
DIP	P31350
IntAct	P31350
	Polymorphism : SNP, mutations, diseases
OMIM	180390    [ map ]
GENECLINICS	180390
SNP	RRM2 [dbSNP-NCBI]
SNP	NM_001034 [SNP-NCI]
SNP	RRM2 [GeneSNPs - Utah]  RRM2] [HGBASE - SRS]
HAPMAP	RRM2 [HAPMAP]
COSMIC	RRM2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RRM2
	General knowledge
Family Browser	RRM2 [UCSC Family Browser]
SOURCE	NM_001034
SMD	Hs.226390
SAGE	Hs.226390
Enzyme	1.17.4.1 [ Enzyme-Expasy ]   1.17.4.1 [ Enzyme-SRS ]   1.17.4.1 [ IntEnz-EBI ]   1.17.4.1 [ BRENDA ]   1.17.4.1 [ KEGG ]   1.17.4.1 [ WIT ]
GO	ribonucleoside-diphosphate reductase activity [Amigo]  ribonucleoside-diphosphate reductase activity
GO	iron ion binding [Amigo]  iron ion binding
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	DNA replication [Amigo]  DNA replication
GO	deoxyribonucleoside diphosphate metabolic process [Amigo]  deoxyribonucleoside diphosphate metabolic process
GO	oxidoreductase activity [Amigo]  oxidoreductase activity
GO	oxidation reduction [Amigo]  oxidation reduction
KEGG	Purine metabolism
KEGG	Pyrimidine metabolism
PubGene	RRM2
TreeFam	RRM2
CTD	6241 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RRM2 Related clones (RZPD - Berlin)
	PubMed
PubMed	26 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:30:28 2008