SKP2 (S-phase kinase-associated protein 2 (p45))

Identity

Other names	FBL1
	FBXL1
	FLB1
	MGC1366
HGNC	SKP2
Location	5p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SKP2   10901
Entrez_Gene	SKP2  6502  S-phase kinase-associated protein 2 (p45)
	Cards
GeneCards	SKP2
Ensembl	SKP2 [Search_View]   ENSG00000145604 [Gene_View]
Genatlas	SKP2
GeneLynx	SKP2
eGenome	SKP2
euGene	6502
	Genomic and cartography
GoldenPath	SKP2  -  5p13   chr5:36187946-36218033 +  5p13.2   [Description]    (hg18-March_2006)
Ensembl	SKP2 - 5p13.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SKP2
	Gene and transcription
Genbank	AB050979 [ ENTREZ ]
Genbank	AB050980 [ ENTREZ ]
Genbank	AB050981 [ ENTREZ ]
Genbank	AK291255 [ ENTREZ ]
Genbank	AK295152 [ ENTREZ ]
RefSeq	NM_005983 [ SRS ]    NM_005983 [ ENTREZ ]
RefSeq	NM_032637 [ SRS ]    NM_032637 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_006576 [ SRS ]    NT_006576 [ ENTREZ ]
RefSeq	NW_001838933 [ SRS ]    NW_001838933 [ ENTREZ ]
RefSeq	NW_922596 [ SRS ]    NW_922596 [ ENTREZ ]
AceView	SKP2 AceView - NCBI
Unigene	Hs.23348 [ SRS ]    Hs.23348 [ NCBI ]     HS23348 [ spliceNest ]
Fast-db	2642 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q13309 [ SRS]    Q13309 [ EXPASY ]     Q13309 [ INTERPRO ]     Q13309 [ UNIPROT ]
Prosite	PS50181 FBOX [ SRS ]    PS50181 FBOX [ Expasy ]
Interpro	IPR001810 F-box [ SRS ]    IPR001810 F-box [ EBI ]
Interpro	IPR001611 LRR [ SRS ]    IPR001611 LRR [ EBI ]
CluSTr	Q13309
Pfam	PF00646 F-box [ SRS ]    PF00646 F-box [ Sanger ]    pfam00646 [ NCBI-CDD ]
Pfam	PF00560 LRR_1 [ SRS ]    PF00560 LRR_1 [ Sanger ]    pfam00560 [ NCBI-CDD ]
Smart	SM00256 FBOX [EMBL]
Blocks	Q13309
PDB	1FQV [ SRS ]    1FQV [ PdbSum ],   1FQV [ IMB ]   1FQV [ RSDB ]
PDB	1FS1 [ SRS ]    1FS1 [ PdbSum ],   1FS1 [ IMB ]   1FS1 [ RSDB ]
PDB	1FS2 [ SRS ]    1FS2 [ PdbSum ],   1FS2 [ IMB ]   1FS2 [ RSDB ]
PDB	1LDK [ SRS ]    1LDK [ PdbSum ],   1LDK [ IMB ]   1LDK [ RSDB ]
PDB	2ASS [ SRS ]    2ASS [ PdbSum ],   2ASS [ IMB ]   2ASS [ RSDB ]
PDB	2AST [ SRS ]    2AST [ PdbSum ],   2AST [ IMB ]   2AST [ RSDB ]
HPRD	03256
	Protein Interaction databases
DIP	Q13309
IntAct	Q13309
	Polymorphism : SNP, mutations, diseases
OMIM	601436    [ map ]
GENECLINICS	601436
SNP	SKP2 [dbSNP-NCBI]
SNP	NM_005983 [SNP-NCI]
SNP	NM_032637 [SNP-NCI]
SNP	SKP2 [GeneSNPs - Utah]  SKP2] [HGBASE - SRS]
HAPMAP	SKP2 [HAPMAP]
COSMIC	SKP2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	SKP2
	General knowledge
Family Browser	SKP2 [UCSC Family Browser]
SOURCE	NM_005983
SOURCE	NM_032637
SMD	Hs.23348
SAGE	Hs.23348
GO	G1/S transition of mitotic cell cycle [Amigo]  G1/S transition of mitotic cell cycle
GO	protein binding [Amigo]  protein binding
GO	cell proliferation [Amigo]  cell proliferation
BIOCARTA	Cell Cycle: G1/S Check Point    [Genes]
BIOCARTA	Regulation of p27 Phosphorylation during Cell Cycle Progression    [Genes]
BIOCARTA	E2F1 Destruction Pathway    [Genes]
KEGG	Cell cycle
KEGG	Ubiquitin mediated proteolysis
PubGene	SKP2
TreeFam	SKP2
CTD	6502 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SKP2 Related clones (RZPD - Berlin)
	PubMed
PubMed	125 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:31:57 2008