SLC2A4 (solute carrier family 2 (facilitated glucose transporter), member 4)

Identity

Other names	GLUT4
HGNC	SLC2A4
Location	17p13
Location_base_pair	Starts at 7125778 and ends at 7132091 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SLC2A4   11009
Entrez_Gene	SLC2A4  6517  solute carrier family 2 (facilitated glucose transporter), member 4
	Cards
GeneCards	SLC2A4
Ensembl	SLC2A4 [Search_View]   ENSG00000181856 [Gene_View]
Genatlas	SLC2A4
GeneLynx	SLC2A4
eGenome	SLC2A4
euGene	6517
	Genomic and cartography
GoldenPath	SLC2A4  -  17p13   chr17:7125778-7132091 +  17p13.1   [Description]    (hg18-March_2006)
Ensembl	SLC2A4 - 17p13.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SLC2A4
	Gene and transcription
Genbank	AK313372 [ ENTREZ ]
Genbank	AL521328 [ ENTREZ ]
Genbank	BC034387 [ ENTREZ ]
Genbank	BC069615 [ ENTREZ ]
Genbank	BC069621 [ ENTREZ ]
RefSeq	NM_001042 [ SRS ]    NM_001042 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	SLC2A4 AceView - NCBI
Unigene	Hs.380691 [ SRS ]    Hs.380691 [ NCBI ]     HS380691 [ spliceNest ]
Fast-db	2825 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P14672 [ SRS]    P14672 [ EXPASY ]     P14672 [ INTERPRO ]     P14672 [ UNIPROT ]
Prosite	PS50850 MFS [ SRS ]    PS50850 MFS [ Expasy ]
Prosite	PS00216 SUGAR_TRANSPORT_1 [ SRS ]    PS00216 SUGAR_TRANSPORT_1 [ Expasy ]
Prosite	PS00217 SUGAR_TRANSPORT_2 [ SRS ]    PS00217 SUGAR_TRANSPORT_2 [ Expasy ]
Interpro	IPR002441 Glu_transpt4 [ SRS ]    IPR002441 Glu_transpt4 [ EBI ]
Interpro	IPR000803 Gluc_transporter [ SRS ]    IPR000803 Gluc_transporter [ EBI ]
Interpro	IPR007114 MFS [ SRS ]    IPR007114 MFS [ EBI ]
Interpro	IPR005828 Sub_transporter [ SRS ]    IPR005828 Sub_transporter [ EBI ]
Interpro	IPR003663 Sugar/inositol_transpt [ SRS ]    IPR003663 Sugar/inositol_transpt [ EBI ]
Interpro	IPR005829 Sugar_transporter_CS [ SRS ]    IPR005829 Sugar_transporter_CS [ EBI ]
CluSTr	P14672
Pfam	PF00083 Sugar_tr [ SRS ]    PF00083 Sugar_tr [ Sanger ]    pfam00083 [ NCBI-CDD ]
Blocks	P14672
HPRD	00688
	Protein Interaction databases
DIP	P14672
IntAct	P14672
	Polymorphism : SNP, mutations, diseases
OMIM	138190    [ map ]
GENECLINICS	138190
SNP	SLC2A4 [dbSNP-NCBI]
SNP	NM_001042 [SNP-NCI]
SNP	SLC2A4 [GeneSNPs - Utah]  SLC2A4] [HGBASE - SRS]
HAPMAP	SLC2A4 [HAPMAP]
HGMD	SLC2A4
	General knowledge
Family Browser	SLC2A4 [UCSC Family Browser]
SOURCE	NM_001042
SMD	Hs.380691
SAGE	Hs.380691
GO	integral to membrane of membrane fraction [Amigo]  integral to membrane of membrane fraction
GO	transporter activity [Amigo]  transporter activity
GO	sugar:hydrogen symporter activity [Amigo]  sugar:hydrogen symporter activity
GO	glucose transmembrane transporter activity [Amigo]  glucose transmembrane transporter activity
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	endosome [Amigo]  endosome
GO	microsome [Amigo]  microsome
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	carbohydrate metabolic process [Amigo]  carbohydrate metabolic process
GO	carbohydrate transport [Amigo]  carbohydrate transport
GO	external side of plasma membrane [Amigo]  external side of plasma membrane
GO	vesicle membrane [Amigo]  vesicle membrane
GO	glucose transport [Amigo]  glucose transport
GO	substrate-specific transmembrane transporter activity [Amigo]  substrate-specific transmembrane transporter activity
GO	trans-Golgi network transport vesicle [Amigo]  trans-Golgi network transport vesicle
GO	glucose homeostasis [Amigo]  glucose homeostasis
GO	perinuclear region of cytoplasm [Amigo]  perinuclear region of cytoplasm
GO	transmembrane transport [Amigo]  transmembrane transport
BIOCARTA	Growth Hormone Signaling Pathway    [Genes]
BIOCARTA	Insulin Signaling Pathway    [Genes]
BIOCARTA	Regulation of PGC-1a    [Genes]
KEGG	Insulin signaling pathway
KEGG	Adipocytokine signaling pathway
KEGG	Type II diabetes mellitus
PubGene	SLC2A4
TreeFam	SLC2A4
CTD	6517 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SLC2A4 Related clones (RZPD - Berlin)
	PubMed
PubMed	67 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:55:18 2008