SLIT2 (slit homolog 2 (Drosophila))

Identity

Other names	FLJ14420
	SLIL3
	Slit-2
Hugo	SLIT2
Location	4p15.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	SLIT2
GDB	SLIT2
Entrez_Gene	SLIT2  9353  slit homolog 2 (Drosophila)
	Cards
GeneCards	SLIT2
Ensembl	SLIT2 [Search_View]   ENSG00000145147 [Gene_View]
Genatlas	SLIT2
GeneLynx	SLIT2
eGenome	SLIT2
euGene	9353
	Genomic and cartography
GoldenPath	SLIT2  -  4p15.2   chr4:19864333-20229886 +  4p15.31   [Description]    (hg18-March_2006)
Ensembl	SLIT2 - 4p15.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SLIT2
	Gene and transcription
Genbank	AB017168 [ ENTREZ ]
Genbank	AF055585 [ ENTREZ ]
Genbank	AF133270 [ ENTREZ ]
Genbank	AK027326 [ ENTREZ ]
Genbank	AK126459 [ ENTREZ ]
RefSeq	NM_004787 [ SRS ]    NM_004787 [ ENTREZ ]
RefSeq	AC_000047 [ SRS ]    AC_000047 [ ENTREZ ]
RefSeq	AC_000136 [ SRS ]    AC_000136 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NT_006316 [ SRS ]    NT_006316 [ ENTREZ ]
RefSeq	NW_001838900 [ SRS ]    NW_001838900 [ ENTREZ ]
RefSeq	NW_922073 [ SRS ]    NW_922073 [ ENTREZ ]
AceView	SLIT2 AceView - NCBI
Unigene	Hs.709761 [ SRS ]    Hs.709761 [ NCBI ]     HS709761 [ spliceNest ]
Fast-db	2811 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O94813 [ SRS]    O94813 [ EXPASY ]     O94813 [ INTERPRO ]
Prosite	PS00010 ASX_HYDROXYL [ SRS ]    PS00010 ASX_HYDROXYL [ Expasy ]
Prosite	PS01185 CTCK_1 [ SRS ]    PS01185 CTCK_1 [ Expasy ]
Prosite	PS01225 CTCK_2 [ SRS ]    PS01225 CTCK_2 [ Expasy ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS01187 EGF_CA [ SRS ]    PS01187 EGF_CA [ Expasy ]
Prosite	PS50025 LAM_G_DOMAIN [ SRS ]    PS50025 LAM_G_DOMAIN [ Expasy ]
Interpro	IPR000152 Asx_hydroxyl_S [ SRS ]    IPR000152 Asx_hydroxyl_S [ EBI ]
Interpro	IPR013320 ConA_like_subgrp [ SRS ]    IPR013320 ConA_like_subgrp [ EBI ]
Interpro	IPR006207 Cys_knot_C [ SRS ]    IPR006207 Cys_knot_C [ EBI ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR001881 EGF_Ca_bd [ SRS ]    IPR001881 EGF_Ca_bd [ EBI ]
Interpro	IPR006209 EGF_like [ SRS ]    IPR006209 EGF_like [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR003645 Fol_N [ SRS ]    IPR003645 Fol_N [ EBI ]
Interpro	IPR002272 FSH_rcpt [ SRS ]    IPR002272 FSH_rcpt [ EBI ]
Interpro	IPR001791 Laminin_G [ SRS ]    IPR001791 Laminin_G [ EBI ]
Interpro	IPR012680 Laminin_G_2 [ SRS ]    IPR012680 Laminin_G_2 [ EBI ]
Interpro	IPR001611 LRR [ SRS ]    IPR001611 LRR [ EBI ]
Interpro	IPR000483 LRR_C [ SRS ]    IPR000483 LRR_C [ EBI ]
Interpro	IPR000372 LRR_cys_N [ SRS ]    IPR000372 LRR_cys_N [ EBI ]
Interpro	IPR003591 LRR_sub-typ [ SRS ]    IPR003591 LRR_sub-typ [ EBI ]
CluSTr	O94813
Pfam	PF00008 EGF [ SRS ]    PF00008 EGF [ Sanger ]    pfam00008 [ NCBI-CDD ]
Pfam	PF02210 Laminin_G_2 [ SRS ]    PF02210 Laminin_G_2 [ Sanger ]    pfam02210 [ NCBI-CDD ]
Pfam	PF00560 LRR_1 [ SRS ]    PF00560 LRR_1 [ Sanger ]    pfam00560 [ NCBI-CDD ]
Pfam	PF01463 LRRCT [ SRS ]    PF01463 LRRCT [ Sanger ]    pfam01463 [ NCBI-CDD ]
Pfam	PF01462 LRRNT [ SRS ]    PF01462 LRRNT [ Sanger ]    pfam01462 [ NCBI-CDD ]
Smart	SM00041 CT [EMBL]
Smart	SM00181 EGF [EMBL]
Smart	SM00179 EGF_CA [EMBL]
Smart	SM00274 FOLN [EMBL]
Smart	SM00282 LamG [EMBL]
Smart	SM00369 LRR_TYP [EMBL]
Smart	SM00082 LRRCT [EMBL]
Smart	SM00013 LRRNT [EMBL]
Blocks	O94813
PDB	SLIT2 [ SRS ]    SLIT2 [ PdbSum ],   SLIT2 [ IMB ]   SLIT2 [ RSDB ]
HPRD	04776
	Protein Interaction databases
DIP	O94813
IntAct	O94813
	Polymorphism : SNP, mutations, diseases
OMIM	603746    [ map ]
GENECLINICS	603746
SNP	SLIT2 [dbSNP-NCBI]
SNP	NM_004787 [SNP-NCI]
SNP	SLIT2 [GeneSNPs - Utah]  SLIT2] [HGBASE - SRS]
HAPMAP	SLIT2 [HAPMAP]
HGMD	SLIT2
	General knowledge
Family Browser	SLIT2 [UCSC Family Browser]
SOURCE	NM_004787
SMD	Hs.709761
SAGE	Hs.709761
GO	ureteric bud development [Amigo]  ureteric bud development
GO	follicle-stimulating hormone receptor activity [Amigo]  follicle-stimulating hormone receptor activity
GO	receptor binding [Amigo]  receptor binding
GO	calcium ion binding [Amigo]  calcium ion binding
GO	extracellular region [Amigo]  extracellular region
GO	chemotaxis [Amigo]  chemotaxis
GO	G-protein coupled receptor protein signaling pathway [Amigo]  G-protein coupled receptor protein signaling pathway
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	nervous system development [Amigo]  nervous system development
GO	mesoderm migration [Amigo]  mesoderm migration
GO	sensory perception of smell [Amigo]  sensory perception of smell
GO	neuron recognition [Amigo]  neuron recognition
GO	motor axon guidance [Amigo]  motor axon guidance
GO	glial cell migration [Amigo]  glial cell migration
GO	integral to membrane [Amigo]  integral to membrane
GO	cell differentiation [Amigo]  cell differentiation
GO	positive regulation of axonogenesis [Amigo]  positive regulation of axonogenesis
GO	induction of negative chemotaxis [Amigo]  induction of negative chemotaxis
GO	induction of negative chemotaxis [Amigo]  induction of negative chemotaxis
KEGG	Axon guidance
PubGene	SLIT2
TreeFam	SLIT2
CTD	9353 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SLIT2 Related clones (RZPD - Berlin)
	PubMed
PubMed	38 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 14 17:27:42 2008