SMAD7 (SMAD family member 7)

Identity

Other names	FLJ16482
	MADH7
	MADH8
HGNC	SMAD7
Location	18q21.1
Location_base_pair	Starts at 44700221 and ends at 44731079 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SMAD7   6773
Entrez_Gene	SMAD7  4092  SMAD family member 7
	Cards
GeneCards	SMAD7
Ensembl	ENSG00000101665 [Gene_View]  SMAD7 [Vega]
Genatlas	SMAD7
	Genomic and cartography
GoldenPath	SMAD7  -  18q21.1   chr18:44700221-44731079 -  18q21.1   [Description]    (hg18-March_2006)
Ensembl	SMAD7 - 18q21.1 [CytoView]
NCBI	Mapview
OMIM	114500 Disease map [OMIM]
OMIM	602932 Disease map [OMIM]
HomoloGene	SMAD7
	Gene and transcription
Genbank	AF010193 [ ENTREZ ]
Genbank	AF015261 [ ENTREZ ]
Genbank	AK131394 [ ENTREZ ]
Genbank	BC074818 [ ENTREZ ]
Genbank	BC074819 [ ENTREZ ]
RefSeq	NM_005904 [ SRS ]    NM_005904 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010966 [ SRS ]    NT_010966 [ ENTREZ ]
RefSeq	NW_001838468 [ SRS ]    NW_001838468 [ ENTREZ ]
RefSeq	NW_927106 [ SRS ]    NW_927106 [ ENTREZ ]
CCDS	SMAD7 CCDS - NCBI
AceView	SMAD7 AceView - NCBI
Unigene	Hs.465087 [ SRS ]    Hs.465087 [ NCBI ]
Fast-db	4210 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O15105 [ SRS]    O15105 [ EXPASY ]     O15105 [ INTERPRO ]     O15105 [ UNIPROT ] O15105 [ VarSplice FASTA ]
Prosite	PS51075 MH1 [ SRS ]    PS51075 MH1 [ Expasy ]
Prosite	PS51076 MH2 [ SRS ]    PS51076 MH2 [ Expasy ]
Interpro	IPR013790 Dwarfin [ SRS ]    IPR013790 Dwarfin [ EBI ]
Interpro	IPR013019 MAD_MH1 [ SRS ]    IPR013019 MAD_MH1 [ EBI ]
Interpro	IPR003619 MH1_Dwarfin-type [ SRS ]    IPR003619 MH1_Dwarfin-type [ EBI ]
Interpro	IPR017855 SMAD_dom-like [ SRS ]    IPR017855 SMAD_dom-like [ EBI ]
Interpro	IPR001132 SMAD_dom_Dwarfin-type [ SRS ]    IPR001132 SMAD_dom_Dwarfin-type [ EBI ]
CluSTr	O15105
Pfam	PF03165 MH1 [ SRS ]    PF03165 MH1 [ Sanger ]    pfam03165 [ NCBI-CDD ]
Pfam	PF03166 MH2 [ SRS ]    PF03166 MH2 [ Sanger ]    pfam03166 [ NCBI-CDD ]
Smart	SM00523 DWA [EMBL]
Smart	SM00524 DWB [EMBL]
Blocks	O15105
PDB	2DJY [ SRS ]    2DJY [ PdbSum ],   2DJY [ IMB ]   2DJY [ RSDB ]
HPRD	04241
	Protein Interaction databases
DIP	O15105
IntAct	O15105
	Polymorphism : SNP, mutations, diseases
OMIM	114500    [ map ]
OMIM	602932    [ map ]
GENETests	114500
GENETests	602932
SNP	SMAD7 [dbSNP-NCBI]
SNP	NM_005904 [SNP-NCI]
SNP	SMAD7 [GeneSNPs - Utah]  SMAD7] [HGBASE - SRS]
HAPMAP	SMAD7 [HAPMAP]
COSMIC	SMAD7 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	SMAD7
Genetic Association	SMAD7
CDC HuGE	SMAD7
	General knowledge
Family Browser	SMAD7 [UCSC Family Browser]
SOURCE	NM_005904
SMD	Hs.465087
SAGE	Hs.465087
GO	transcription factor activity [Amigo]  transcription factor activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	transcription factor complex [Amigo]  transcription factor complex
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	response to stress [Amigo]  response to stress
GO	transforming growth factor beta receptor signaling pathway [Amigo]  transforming growth factor beta receptor signaling pathway
GO	BMP signaling pathway [Amigo]  BMP signaling pathway
GO	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity [Amigo]  transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
KEGG	TGF-beta signaling pathway
PubGene	SMAD7
TreeFam	SMAD7
CTD	4092 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SMAD7 Related clones (RZPD - Berlin)
	PubMed
PubMed	94 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 17:09:09 2008