SMG1 (PI-3-kinase-related kinase SMG-1)

Identity

Other names	61E3.4
	ATX
	KIAA0421
	LIP
HGNC	-
Location	16p12.3
Location_base_pair	Starts at 18723676 and ends at 18844887 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	-   -
Entrez_Gene	SMG1  23049  PI-3-kinase-related kinase SMG-1
	Cards
GeneCards	SMG1
Ensembl	SMG1 [Search_View]   ENSG00000157106 [Gene_View]
Genatlas	SMG1
GeneLynx	SMG1
eGenome	SMG1
euGene	23049
	Genomic and cartography
GoldenPath	SMG1  -  16p12.3   chr16:18723676-18844887 -  16p12.3   [Description]    (hg18-March_2006)
Ensembl	SMG1 - 16p12.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SMG1
	Gene and transcription
Genbank	AB007881 [ ENTREZ ]
Genbank	AB061371 [ ENTREZ ]
Genbank	AF186377 [ ENTREZ ]
Genbank	AF395444 [ ENTREZ ]
Genbank	AK025794 [ ENTREZ ]
RefSeq	NM_015092 [ SRS ]    NM_015092 [ ENTREZ ]
RefSeq	AC_000059 [ SRS ]    AC_000059 [ ENTREZ ]
RefSeq	AC_000148 [ SRS ]    AC_000148 [ ENTREZ ]
RefSeq	NC_000016 [ SRS ]    NC_000016 [ ENTREZ ]
RefSeq	NT_010393 [ SRS ]    NT_010393 [ ENTREZ ]
RefSeq	NW_001838381 [ SRS ]    NW_001838381 [ ENTREZ ]
RefSeq	NW_926151 [ SRS ]    NW_926151 [ ENTREZ ]
AceView	SMG1 AceView - NCBI
Unigene	Hs.460179 [ SRS ]    Hs.460179 [ NCBI ]     HS460179 [ spliceNest ]
Fast-db	4586 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q96Q15 [ SRS]    Q96Q15 [ EXPASY ]     Q96Q15 [ INTERPRO ]     Q96Q15 [ UNIPROT ]
Prosite	PS51189 FAT [ SRS ]    PS51189 FAT [ Expasy ]
Prosite	PS51190 FATC [ SRS ]    PS51190 FATC [ Expasy ]
Prosite	PS50077 HEAT_REPEAT [ SRS ]    PS50077 HEAT_REPEAT [ Expasy ]
Prosite	PS00915 PI3_4_KINASE_1 [ SRS ]    PS00915 PI3_4_KINASE_1 [ Expasy ]
Prosite	PS00916 PI3_4_KINASE_2 [ SRS ]    PS00916 PI3_4_KINASE_2 [ Expasy ]
Prosite	PS50290 PI3_4_KINASE_3 [ SRS ]    PS50290 PI3_4_KINASE_3 [ Expasy ]
Interpro	IPR015519 Ataxia_Telang_Mut [ SRS ]    IPR015519 Ataxia_Telang_Mut [ EBI ]
Interpro	IPR003152 FATC [ SRS ]    IPR003152 FATC [ EBI ]
Interpro	IPR000357 HEAT [ SRS ]    IPR000357 HEAT [ EBI ]
Interpro	IPR000403 PI3/4_kinase_cat [ SRS ]    IPR000403 PI3/4_kinase_cat [ EBI ]
Interpro	IPR014009 PIK_FAT [ SRS ]    IPR014009 PIK_FAT [ EBI ]
CluSTr	Q96Q15
Pfam	PF02260 FATC [ SRS ]    PF02260 FATC [ Sanger ]    pfam02260 [ NCBI-CDD ]
Pfam	PF02985 HEAT [ SRS ]    PF02985 HEAT [ Sanger ]    pfam02985 [ NCBI-CDD ]
Pfam	PF00454 PI3_PI4_kinase [ SRS ]    PF00454 PI3_PI4_kinase [ Sanger ]    pfam00454 [ NCBI-CDD ]
Smart	SM00146 PI3Kc [EMBL]
Blocks	Q96Q15
HPRD	06123
	Protein Interaction databases
DIP	Q96Q15
IntAct	Q96Q15
	Polymorphism : SNP, mutations, diseases
OMIM	607032    [ map ]
GENECLINICS	607032
SNP	SMG1 [dbSNP-NCBI]
SNP	NM_015092 [SNP-NCI]
SNP	SMG1 [GeneSNPs - Utah]  SMG1] [HGBASE - SRS]
HAPMAP	SMG1 [HAPMAP]
COSMIC	SMG1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	-
	General knowledge
Family Browser	SMG1 [UCSC Family Browser]
SOURCE	NM_015092
SMD	Hs.460179
SAGE	Hs.460179
Enzyme	2.7.11.1 [ Enzyme-Expasy ]   2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   2.7.11.1 [ WIT ]
GO	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Amigo]  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Amigo]  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Amigo]  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO	inositol or phosphatidylinositol kinase activity [Amigo]  inositol or phosphatidylinositol kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	DNA repair [Amigo]  DNA repair
GO	mRNA export from nucleus [Amigo]  mRNA export from nucleus
GO	transferase activity [Amigo]  transferase activity
GO	peptidyl-serine phosphorylation [Amigo]  peptidyl-serine phosphorylation
GO	peptidyl-serine phosphorylation [Amigo]  peptidyl-serine phosphorylation
GO	manganese ion binding [Amigo]  manganese ion binding
GO	protein amino acid autophosphorylation [Amigo]  protein amino acid autophosphorylation
GO	phosphoinositide phosphorylation [Amigo]  phosphoinositide phosphorylation
GO	metal ion binding [Amigo]  metal ion binding
PubGene	SMG1
TreeFam	-
CTD	23049 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	- Related clones (RZPD - Berlin)
	PubMed
PubMed	20 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:32:56 2008