SYNJ1 (synaptojanin 1)

Identity

Other names	INPP5G
HGNC	SYNJ1
Location	21q22.2
Location_base_pair	Starts at 32922944 and ends at 33022148 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SYNJ1   11503
Entrez_Gene	SYNJ1  8867  synaptojanin 1
	Cards
GeneCards	SYNJ1
Ensembl	SYNJ1 [Search_View]   ENSG00000159082 [Gene_View]
Genatlas	SYNJ1
GeneLynx	SYNJ1
eGenome	SYNJ1
euGene	8867
	Genomic and cartography
GoldenPath	SYNJ1  -  21q22.2   chr21:32922944-33022148 -  21q22.11   [Description]    (hg18-March_2006)
Ensembl	SYNJ1 - 21q22.11 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SYNJ1
	Gene and transcription
Genbank	AB020717 [ ENTREZ ]
Genbank	AF009039 [ ENTREZ ]
Genbank	AF009040 [ ENTREZ ]
Genbank	AK307762 [ ENTREZ ]
Genbank	BC019630 [ ENTREZ ]
RefSeq	NM_003895 [ SRS ]    NM_003895 [ ENTREZ ]
RefSeq	NM_203446 [ SRS ]    NM_203446 [ ENTREZ ]
RefSeq	AC_000064 [ SRS ]    AC_000064 [ ENTREZ ]
RefSeq	AC_000153 [ SRS ]    AC_000153 [ ENTREZ ]
RefSeq	NC_000021 [ SRS ]    NC_000021 [ ENTREZ ]
RefSeq	NT_011512 [ SRS ]    NT_011512 [ ENTREZ ]
RefSeq	NW_001838706 [ SRS ]    NW_001838706 [ ENTREZ ]
RefSeq	NW_927384 [ SRS ]    NW_927384 [ ENTREZ ]
AceView	SYNJ1 AceView - NCBI
Unigene	Hs.473632 [ SRS ]    Hs.473632 [ NCBI ]     HS473632 [ spliceNest ]
Fast-db	1750 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O43426 [ SRS]    O43426 [ EXPASY ]     O43426 [ INTERPRO ]     O43426 [ UNIPROT ]
Prosite	PS50102 RRM [ SRS ]    PS50102 RRM [ Expasy ]
Prosite	PS50275 SAC [ SRS ]    PS50275 SAC [ Expasy ]
Interpro	IPR015047 DUF1866 [ SRS ]    IPR015047 DUF1866 [ EBI ]
Interpro	IPR005135 Endo/exonuclease/phosphatase [ SRS ]    IPR005135 Endo/exonuclease/phosphatase [ EBI ]
Interpro	IPR000300 IPPc [ SRS ]    IPR000300 IPPc [ EBI ]
Interpro	IPR000504 RRM_RNP1 [ SRS ]    IPR000504 RRM_RNP1 [ EBI ]
Interpro	IPR002013 Syja_N [ SRS ]    IPR002013 Syja_N [ EBI ]
CluSTr	O43426
Pfam	PF08952 DUF1866 [ SRS ]    PF08952 DUF1866 [ Sanger ]    pfam08952 [ NCBI-CDD ]
Pfam	PF03372 Exo_endo_phos [ SRS ]    PF03372 Exo_endo_phos [ Sanger ]    pfam03372 [ NCBI-CDD ]
Pfam	PF02383 Syja_N [ SRS ]    PF02383 Syja_N [ Sanger ]    pfam02383 [ NCBI-CDD ]
Smart	SM00128 IPPc [EMBL]
Blocks	O43426
PDB	1W80 [ SRS ]    1W80 [ PdbSum ],   1W80 [ IMB ]   1W80 [ RSDB ]
PDB	2DNR [ SRS ]    2DNR [ PdbSum ],   2DNR [ IMB ]   2DNR [ RSDB ]
PDB	2VJ0 [ SRS ]    2VJ0 [ PdbSum ],   2VJ0 [ IMB ]   2VJ0 [ RSDB ]
HPRD	09182
	Protein Interaction databases
DIP	O43426
IntAct	O43426
	Polymorphism : SNP, mutations, diseases
OMIM	604297    [ map ]
GENECLINICS	604297
SNP	SYNJ1 [dbSNP-NCBI]
SNP	NM_003895 [SNP-NCI]
SNP	NM_203446 [SNP-NCI]
SNP	SYNJ1 [GeneSNPs - Utah]  SYNJ1] [HGBASE - SRS]
HAPMAP	SYNJ1 [HAPMAP]
COSMIC	SYNJ1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	SYNJ1
	General knowledge
Family Browser	SYNJ1 [UCSC Family Browser]
SOURCE	NM_003895
SOURCE	NM_203446
SMD	Hs.473632
SAGE	Hs.473632
Enzyme	3.1.3.36 [ Enzyme-Expasy ]   3.1.3.36 [ Enzyme-SRS ]   3.1.3.36 [ IntEnz-EBI ]   3.1.3.36 [ BRENDA ]   3.1.3.36 [ KEGG ]   3.1.3.36 [ WIT ]
GO	nucleic acid binding [Amigo]  nucleic acid binding
GO	RNA binding [Amigo]  RNA binding
GO	inositol or phosphatidylinositol phosphatase activity [Amigo]  inositol or phosphatidylinositol phosphatase activity
GO	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [Amigo]  phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO	inositol-polyphosphate 5-phosphatase activity [Amigo]  inositol-polyphosphate 5-phosphatase activity
GO	cytoplasm [Amigo]  cytoplasm
GO	phosphate metabolic process [Amigo]  phosphate metabolic process
GO	hydrolase activity [Amigo]  hydrolase activity
GO	synaptic vesicle endocytosis [Amigo]  synaptic vesicle endocytosis
BIOCARTA	Endocytotic role of NDK, Phosphins and Dynamin    [Genes]
KEGG	Inositol phosphate metabolism
KEGG	Phosphatidylinositol signaling system
PubGene	SYNJ1
TreeFam	SYNJ1
CTD	8867 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SYNJ1 Related clones (RZPD - Berlin)
	PubMed
PubMed	28 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 15:03:47 2008